日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-cell RNA sequence analysis reveals USP32 as a therapeutic target to mitigate PD-L1-driven colorectal tumorigenesis in vitro and in vivo

单细胞RNA序列分析揭示USP32可作为治疗靶点,在体外和体内均能减轻PD-L1驱动的结直肠肿瘤发生。

Birappa, Girish; Perumalsamy, Haribalan; Hong, Seok-Ho; Gowda, D A Ayush; Chandrasekaran, Arun Pandian; Karapurkar, Janardhan Keshav; Rajkumar, Sripriya; Balusamy, Sri Renukadevi; Jayachandran, Aparna; Baek, Kwang-Hyun; Lee, Junwon; Matam, Viswanathaiah; Kim, Woo Jin; Kim, Kye-Seong; Ramakrishna, Suresh; Suresh, Bharathi

Targeting USP11 counteracts SFTPC(I73T) -associated interstitial lung disease in hiPSCs-derived alveolar organoids and in vivo models.

靶向 USP11 可对抗 hiPSCs 衍生的肺泡类器官和体内模型中 SFTPC(I73T) 相关的间质性肺病

Karapurkar Janardhan Keshav, Rajkumar Sripriya, Jung Ji-Hye, Kim Ji-Young, Birappa Girish, Gowda D A Ayush, Colaco Jencia Carminha, Suresh Bharathi, Choi Jung-Yun, Woo Sang Hyeon, Jo Won-Jun, Lee Jong-Hee, Kim Kye-Seong, Hong Seok-Ho, Ramakrishna Suresh

Multifunctional poly (lactic acid)/vanillin coatings on drug loaded titanium nanotube arrays for improved biocompatibility, corrosion resistance, and antibacterial characteristics

在载药钛纳米管阵列上涂覆多功能聚乳酸/香兰素涂层,以提高其生物相容性、耐腐蚀性和抗菌性能

Kumar, A Madhan; Hussein, M A; Suresh, Bharathi; Ramakrishna, Suresh; Saravanan, S; Javid, Mohamed

A Multikinase Inhibitor AX-0085 Blocks FGFR1 Activation to Overcomes Osimertinib Resistance in Non-Small Cell Lung Cancer.

多激酶抑制剂 AX-0085 可阻断 FGFR1 激活,从而克服非小细胞肺癌对奥希替尼的耐药性。

Rhie Byung-Ho, Karapurkar Janardhan Keshav, Kim Hyun-Yi, Woo Sang Hyeon, Gowda D A Ayush, Kim Dong Ha, Choi Myeong Jun, Park Young Jun, Matam Viswanathaiah, Hong Yoonki, Hong Seok-Ho, Ramakrishna Suresh, Kim Kye-Seong

Ubiquitin specific protease 7 deubiquitinates and regulates Aurora B-mediated cytokinesis.

泛素特异性蛋白酶 7 可去除泛素并调节 Aurora B 介导的胞质分裂

Kaushal Kamini, Antao Ainsley Mike, Das Soumyadip, Kim Sammy L, Birappa Girish, Rajkumar Sripriya, Gowda D A Ayush, Ajaykumar C Bindu, Singh Vijai, Kim Keesung, Suresh Bharathi, Ramakrishna Suresh

An Efficient Endothelial Cell Differentiation Protocol Using Bioactive Lipid O-Cyclic Phytosphingosine-1-Phosphate in Human Embryonic Stem Cells

利用生物活性脂质O-环状植物鞘氨醇-1-磷酸酯在人胚胎干细胞中高效诱导内皮细胞分化

Jo, Ki-Sang; Jo, Won-Jun; Antao, Ainsley Mike; Karapurkar, Janardhan Keshav; Park, Young Jun; Choi, Myeong-Jun; Ramakrishna, Suresh; Kim, Kye-Seong

Loss of Ubiquitin-Specific Protease 11 Mitigates Pulmonary Fibrosis in Human Pluripotent Stem Cell-Derived Alveolar Organoids.

泛素特异性蛋白酶 11 的缺失可减轻人类多能干细胞衍生肺泡类器官的肺纤维化

Rajkumar Sripriya, Jung Ji-Hye, Kim Ji-Young, Karapurkar Janardhan Keshav, Birappa Girish, Gowda D A Ayush, Ajaykumar C Bindu, Perumalsamy Haribalan, Suresh Bharathi, Kim Kye-Seong, Hong Seok-Ho, Ramakrishna Suresh

Usp7 Regulates Glial Lineage Cell-Specific Transcription Factors by Modulating Histone H2B Monoubiquitination

Usp7通过调节组蛋白H2B单泛素化来调控神经胶质细胞谱系特异性转录因子。

Kim, Dong-Ho; Kim, Sammy L; Singh, Vijai; Ramakrishna, Suresh

Phage engineering and phage-assisted CRISPR-Cas delivery to combat multidrug-resistant pathogens

利用噬菌体工程和噬菌体辅助的CRISPR-Cas递送技术对抗多重耐药病原体

Khambhati, Khushal; Bhattacharjee, Gargi; Gohil, Nisarg; Dhanoa, Gurneet K; Sagona, Antonia P; Mani, Indra; Bui, Nhat Le; Chu, Dinh-Toi; Karapurkar, Janardhan Keshav; Jang, Su Hwa; Chung, Hee Yong; Maurya, Rupesh; Alzahrani, Khalid J; Ramakrishna, Suresh; Singh, Vijai

Human pluripotent stem cell-derived macrophages and macrophage-derived exosomes: therapeutic potential in pulmonary fibrosis

人类多能干细胞衍生的巨噬细胞和巨噬细胞衍生的外泌体:在肺纤维化治疗中的潜力

Rasaei, Roya; Tyagi, Apoorvi; Rasaei, Shima; Lee, Seung-Joon; Yang, Se-Ran; Kim, Kye-Seong; Ramakrishna, Suresh; Hong, Seok-Ho