日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deletion of the RGD motif from the penton base in oncolytic adenoviruses enhances antitumor efficacy of combined CAR T cell therapy

溶瘤腺病毒中五邻体碱基上的 RGD 基序删除可增强 CAR-T 细胞联合疗法的抗肿瘤功效

Alvaro Morales-Molina, Miguel Angel Rodriguez-Milla, Patricia Garcia-Rodriguez, Laura Hidalgo, Ramon Alemany, Javier Garcia-Castro

KPC pancreatic cancer cells are a novel immunocompetent murine model supporting human adenovirus replication and tumor oncolysis

KPC胰腺癌细胞是一种新型的具有免疫活性的鼠模型,支持人腺病毒复制和肿瘤溶解。

Marc Otero-Mateo,Francesc Estrany Jr,Sabrina Arcas-Márquez,Laura Moya-Borrego,Giancarlo Castellano,Miquel Castany,Ramon Alemany,Cristina Fillat

Immunostimulatory gene therapy targeting CD40, 4-1BB and IL-2R activates DCs and stimulates antigen-specific T-cell and NK-cell responses in melanoma models

靶向 CD40、4-1BB 和 IL-2R 的免疫刺激基因疗法可激活树突状细胞 (DC),并在黑色素瘤模型中刺激抗原特异性 T 细胞和 NK 细胞反应。

Jessica Wenthe ,Emma Eriksson ,Ann-Charlotte Hellström ,Rafael Moreno ,Gustav Ullenhag ,Ramon Alemany ,Tanja Lövgren ,Angelica Loskog

Novel combinatorial therapy of oncolytic adenovirus AdV5/3-D24-ICOSL-CD40L with anti PD-1 exhibits enhanced anti-cancer efficacy through promotion of intratumoral T-cell infiltration and modulation of tumour microenvironment in mesothelioma mouse model

溶瘤腺病毒 AdV5/3-D24-ICOSL-CD40L 与抗 PD-1 的新型组合疗法通过促进间皮瘤小鼠模型中的肿瘤内 T 细胞浸润和调节肿瘤微环境表现出增强的抗癌功效

Mariangela Garofalo, Magdalena Wieczorek, Ines Anders, Monika Staniszewska, Michal Lazniewski, Marta Prygiel, Aleksandra Anna Zasada, Teresa Szczepińska, Dariusz Plewczynski, Stefano Salmaso, Paolo Caliceti, Vincenzo Cerullo, Ramon Alemany, Beate Rinner, Katarzyna Pancer, Lukasz Kuryk

Systemic cellular viroimmunotherapy for canine high-grade gliomas

犬高级别胶质瘤的系统性细胞病毒免疫治疗

Ana Cloquell #, Isidro Mateo #, Stefano Gambera, Martí Pumarola, Ramon Alemany, Javier García-Castro #, Ana Judith Perisé-Barrios #

VCN-01 disrupts pancreatic cancer stroma and exerts antitumor effects

VCN-01破坏胰腺癌基质并发挥抗肿瘤作用

Miriam Bazan-Peregrino ,Rocio Garcia-Carbonero ,Berta Laquente ,Rafael Álvarez ,Ana Mato-Berciano ,Marta Gimenez-Alejandre ,Sara Morgado ,Alba Rodríguez-García ,Maria V Maliandi ,M Carmen Riesco ,Rafael Moreno ,Mireia M Ginestà ,Mercedes Perez-Carreras ,Joan B Gornals ,Susana Prados ,Sofía Perea ,Gabriel Capella ,Ramon Alemany ,Ramon Salazar ,Emma Blasi ,Carmen Blasco ,Manel Cascallo ,Manuel Hidalgo

Modification of Extracellular Matrix Enhances Oncolytic Adenovirus Immunotherapy in Glioblastoma

细胞外基质的修饰增强溶瘤腺病毒免疫疗法在胶质母细胞瘤中的疗效

Juri Kiyokawa ,Yoichiro Kawamura ,Shanawaz M Ghouse ,Simge Acar ,Erinç Barçın ,Jordi Martínez-Quintanilla ,Robert L Martuza ,Ramon Alemany ,Samuel D Rabkin ,Khalid Shah ,Hiroaki Wakimoto

Arming Oncolytic Adenoviruses: Effect of Insertion Site and Splice Acceptor on Transgene Expression and Viral Fitness

武装溶瘤腺病毒:插入位点和剪接受体对转基因表达和病毒适应性的影响

Martí Farrera-Sal, Jana de Sostoa, Estela Nuñez-Manchón, Rafael Moreno, Cristina Fillat, Miriam Bazan-Peregrino, Ramon Alemany

Targeting the tumor stroma with an oncolytic adenovirus secreting a fibroblast activation protein-targeted bispecific T-cell engager

利用分泌成纤维细胞活化蛋白的双特异性 T 细胞接合剂的溶瘤腺病毒靶向肿瘤基质

Jana de Sostoa, Carlos Alberto Fajardo, Rafael Moreno, Maria D Ramos, Martí Farrera-Sal, Ramon Alemany

IL-6 Signaling Blockade during CD40-Mediated Immune Activation Favors Antitumor Factors by Reducing TGF-β, Collagen Type I, and PD-L1/PD-1

CD40 介导的免疫激活过程中 IL-6 信号阻断有利于抗肿瘤因子,从而降低 TGF-β、I 型胶原蛋白和 PD-L1/PD-1

Emma Eriksson, Ioanna Milenova, Jessica Wenthe, Rafael Moreno, Ramon Alemany, Angelica Loskog