Novel combinatorial therapy of oncolytic adenovirus AdV5/3-D24-ICOSL-CD40L with anti PD-1 exhibits enhanced anti-cancer efficacy through promotion of intratumoral T-cell infiltration and modulation of tumour microenvironment in mesothelioma mouse model
溶瘤腺病毒 AdV5/3-D24-ICOSL-CD40L 与抗 PD-1 的新型组合疗法通过促进间皮瘤小鼠模型中的肿瘤内 T 细胞浸润和调节肿瘤微环境表现出增强的抗癌功效
期刊:Frontiers in Oncology
影响因子:3.5
doi:10.3389/fonc.2023.1259314
Mariangela Garofalo, Magdalena Wieczorek, Ines Anders, Monika Staniszewska, Michal Lazniewski, Marta Prygiel, Aleksandra Anna Zasada, Teresa Szczepińska, Dariusz Plewczynski, Stefano Salmaso, Paolo Caliceti, Vincenzo Cerullo, Ramon Alemany, Beate Rinner, Katarzyna Pancer, Lukasz Kuryk