日期:
2020 年 — 2026 年
2020
2021
2022
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2026
影响因子:

A Nonketotic Hyperglycinemia Mouse Shows Wide-Ranging Biochemical Consequences of Elevated Glycine, Reduced Folate One-Carbon Charging, and Serine Deficiency

非酮症高甘氨酸血症小鼠表现出甘氨酸升高、叶酸一碳糖化减少和丝氨酸缺乏引起的广泛生化后果

Swanson, Michael A; Jiang, Hua; Kolora, Lakshmi Divya; Molino, Rachel; Reisdorph, Richard; Michel, Cole R; Doenges, Katrina A; Leung, Kit-Yi; Lin, Xiangping; Wong, Frank; Lancaster, Samual; Michael, Basil; Snyder, Michael; Hock, Daniella H; Stroud, David A; Wood, Tim; Binard, Robert; Anderson-Lehman, Laura; Christians, Uwe; Arning, Erland; Friederich, Marisa W; Van Hove, Roxanne A; MacLean, Kenneth N; Greene, Nicholas D E; Van Hove, Johan L K

Acetylation of proximal cysteine-lysine pairs by alcohol metabolism

酒精代谢引起的近端半胱氨酸-赖氨酸对的乙酰化

McGinnis, Courtney D; Harris, Peter S; Graham, Brenton I M; Marentette, John O; Michel, Cole R; Saba, Laura M; Reisdorph, Richard; Roede, James R; Fritz, Kristofer S

Bi-allelic mutations in FASTKD5 are associated with cytochrome c oxidase deficiency and early- to late-onset Leigh syndrome

FASTKD5基因的双等位基因突变与细胞色素c氧化酶缺乏症以及早发型或晚发型莱氏综合征相关。

Antonicka, Hana; Weraarpachai, Woranontee; Szigety, Katherine M; Kopajtich, Robert; Gibson, James B; Van Hove, Johan L K; Friederich, Marisa W; Lopriore, Piervito; Neuhofer, Christiane; Van Hove, Roxanne A; Cole, Michel A; Reisdorph, Richard; Peterson, James T; Dempsey, Katherine J; Ganetzky, Rebecca D; Mancuso, Michelangelo; Prokisch, Holger; Shoubridge, Eric A

Modulation of the thiol redox proteome by sugarcane ash-derived silica nanoparticles: insights into chronic kidney disease of unknown etiology

甘蔗灰衍生的二氧化硅纳米粒子对硫醇氧化还原蛋白质组的调节:对病因不明的慢性肾病的见解

Arthur D Stem, Cole R Michel, Peter S Harris, Keegan L Rogers, Matthew Gibb, Carlos A Roncal-Jimenez, Richard Reisdorph, Richard J Johnson, James R Roede, Kristofer S Fritz, Jared M Brown

Appearance of green tea compounds in plasma following acute green tea consumption is modulated by the gut microbiome in mice

小鼠急性饮用绿茶后,血浆中绿茶化合物的出现受肠道微生物群的调节。

Sterrett, John D; Quinn, Kevin D; Doenges, Katrina A; Nusbacher, Nichole M; Levens, Cassandra L; Armstrong, Mike L; Reisdorph, Richard M; Smith, Harry; Saba, Laura M; Kuhn, Kristine A; Lozupone, Catherine A; Reisdorph, Nichole A

Dominant negative ATP5F1A variants disrupt oxidative phosphorylation causing neurological disorders.

显性负性 ATP5F1A 变体破坏氧化磷酸化,导致神经系统疾病

Fielder Sara M, Friederich Marisa W, Hock Daniella H, Zhang Jessie R, Valin Liana M, Rosenfeld Jill A, Booth Kevin T A, Brown Natasha J, Rius Rocio, Sharma Tanavi, Semcesen Liana N, Worley Kim C, Burrage Lindsay C, Treat Kayla, Samson Tara, Govert Sarah, DaCunha Sara, Yuan Weimin, Chen Jian, Lesinski Jacob, Hoang Hieu, Morrison Stephanie A, Ladha Farah A, Van Hove Roxanne A, Michel Cole R, Reisdorph Richard, Tycksen Eric, Baldridge Dustin, Silverman Gary A, Soler-Alfonso Claudia, Conboy Erin, Vetrini Francesco, Emrick Lisa, Craigen William J, Sykes Stephen M, Stroud David A, Van Hove Johan L K, Schedl Tim, Pak Stephen C

An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis.

综合多组学方法能够超快速地诊断出 PDHX 基因深内含子致病变异,并对患有乳酸性酸中毒的危重新生儿进行精准治疗

Starosta Rodrigo T, Larson Austin A, Meeks Naomi J L, Gracie Sara, Friederich Marisa W, Gaughan Sommer M, Baker Peter R 2nd, Knupp Kelly G, Michel Cole R, Reisdorph Richard, Hock Daniella H, Stroud David A, Wood Tim, Van Hove Johan L K

ACAD9 treatment with bezafibrate and nicotinamide riboside temporarily stabilizes cardiomyopathy and lactic acidosis.

使用苯扎贝特和烟酰胺核苷治疗 ACAD9 可暂时稳定心肌病和乳酸性酸中毒

Van Hove Johan L K, Friederich Marisa W, Hock Daniella H, Stroud David A, Caruana Nikeisha J, Christians Uwe, Schniedewind Björn, Michel Cole R, Reisdorph Richard, Lopez Gonzalez Edwin D J, Brenner Charles, Donovan Tonia E, Lee Jessica C, Chatfield Kathryn C, Larson Austin A, Baker Peter R 2nd, McCandless Shawn E, Moore Burk Meghan F

Salmon Food-Specific Compounds and Their Metabolites Increase in Human Plasma and Are Associated with Cardiometabolic Health Indicators Following a Mediterranean-Style Diet Intervention

地中海式饮食干预后,人体血浆中鲑鱼特有化合物及其代谢产物含量增加,且与心血管代谢健康指标相关。

Hill, Emily B; Reisdorph, Richard M; Rasolofomanana-Rajery, Sakaiza; Michel, Cole; Khajeh-Sharafabadi, Mobin; Doenges, Katrina A; Weaver, Nicholas; Quinn, Kevin; Sutliff, Aimee K; Tang, Minghua; Borengasser, Sarah J; Frank, Daniel N; O'Connor, Lauren E; Campbell, Wayne W; Krebs, Nancy F; Hendricks, Audrey E; Reisdorph, Nichole A

Dexamethasone targets actin cytoskeleton signaling and inflammatory mediators to reverse sulfur mustard-induced toxicity in rabbit corneas.

地塞米松通过靶向肌动蛋白细胞骨架信号传导和炎症介质来逆转芥子气引起的兔角膜毒性

Kant Rama, Mishra Neha, Kandhari Kushal, Saba Laura, Michel Cole, Reisdorph Richard, Tewari-Singh Neera, Pantcheva Mina B, Petrash J Mark, Agarwal Chapla, Agarwal Rajesh