日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Thermal proteome profiling and proteome analysis using high-definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next-generation galeterone analog VNPP433-3β in castration-resistant prostate cancer.

利用高分辨率质谱进行热蛋白质组分析和蛋白质组分析,证明下一代加列酮类似物 VNPP433-3β 可以调节去势抵抗性前列腺癌中的胆固醇生物合成

Thankan Retheesh S, Thomas Elizabeth, Weldemariam Mehari M, Purushottamachar Puranik, Huang Weiliang, Kane Maureen A, Zhang Yuji, Ambulos Nicholas, Wang Bi-Dar, Weber David, Njar Vincent C O

Adverse Effects Following Immunisation and Vaccine Hesitancy: A Qualitative Study in a South Indian District

免疫接种后的不良反应和疫苗犹豫:印度南部某地区的一项定性研究

Gopalan, Retheesh Babu; Babu, Bontha V; Sarma S, Krishna; John, Rooth P

COVID-19 vaccine acceptance and hesitancy in Indian context: a systematic review and meta-analysis

印度背景下新冠疫苗接受度和犹豫度:系统评价和荟萃分析

Dey, Sangeeta; Kusuma, Yadlapalli S; Kant, Shashi; Kumar, Dewesh; Gopalan, Retheesh Babu; Sridevi, Parikipandla; Aggarwal, Sumit

Evaluation of potential role of R-loop and G-quadruplex DNA in the fragility of c-MYC during chromosomal translocation associated with Burkitt's lymphoma

评估 R-环和 G-四链体 DNA 在伯基特淋巴瘤相关染色体易位过程中对 c-MYC 脆性的潜在作用

Nitu Kumari, Kohal Das, Shivangi Sharma, Sumedha Dahal, Sagar Sanjiv Desai, Urbi Roy, Anju Sharma, Meghana Manjunath, Vidya Gopalakrishnan, S T Retheesh, Saniya M Javadekar, Bibha Choudhary, Sathees C Raghavan

VNLG-152R and its deuterated analogs potently inhibit/repress triple/quadruple negative breast cancer of diverse racial origins in vitro and in vivo by upregulating E3 Ligase Synoviolin 1 (SYVN1) and inducing proteasomal degradation of MNK1/2

VNLG-152R及其氘代类似物通过上调E3连接酶Synoviolin 1 (SYVN1)并诱导MNK1/2的蛋白酶体降解,在体外和体内有效抑制/抑制不同种族来源的三阴性/四阴性乳腺癌。

Thankan, Retheesh S; Thomas, Elizabeth; Purushottamachar, Puranik; Weber, David J; Ramamurthy, Vidya P; Huang, Weiliang; Kane, Maureen A; Njar, Vincent C O

Murine toxicology and pharmacokinetics of lead next generation galeterone analog, VNPP433-3β

下一代加列酮类似物VNPP433-3β的鼠毒理学和药代动力学研究

Thomas, Elizabeth; Thankan, Retheesh S; Purushottamachar, Puranik; Guo, Jianxia; Parise, Robert A; Beumer, Jan H; Njar, Vincent C O

Targeted Degradation of Androgen Receptor by VNPP433-3β in Castration-Resistant Prostate Cancer Cells Implicates Interaction with E3 Ligase MDM2 Resulting in Ubiquitin-Proteasomal Degradation

VNPP433-3β 在去势抵抗性前列腺癌细胞中靶向降解雄激素受体,提示其与 E3 连接酶 MDM2 相互作用,导致泛素-蛋白酶体降解

Elizabeth Thomas, Retheesh S Thankan, Puranik Purushottamachar, David J Weber, Vincent C O Njar

Towards Upcycling Biomass-Derived Crosslinked Polymers with Light

利用光对生物质衍生交联聚合物进行升级再造

Singathi, Ravichandranath; Raghunathan, Ramya; Krishnan, Retheesh; Kumar Rajendran, Saravana; Baburaj, Sruthy; Sibi, Mukund P; Webster, Dean C; Sivaguru, Jayaraman

Novel AR/AR-V7 and Mnk1/2 Degrader, VNPP433-3β: Molecular Mechanisms of Action and Efficacy in AR-Overexpressing Castration Resistant Prostate Cancer In Vitro and In Vivo Models

新型 AR/AR-V7 和 Mnk1/2 降解剂 VNPP433-3β:在体外和体内模型中 AR 过表达去势抵抗性前列腺癌的作用和疗效的分子机制

Elizabeth Thomas, Retheesh S Thankan, Puranik Purushottamachar, Weiliang Huang, Maureen A Kane, Yuji Zhang, Nicholas P Ambulos, David J Weber, Vincent C O Njar

Global COVID-19 Transmission and Mortality-Influence of Human Development, Climate, and Climate Variability on Early Phase of the Pandemic

全球新冠肺炎传播与死亡率——人类发展、气候及气候变率对疫情早期阶段的影响

Thazhathedath Hariharan, Hariprasad; Surendran, Anish Thekkumkara; Haridasan, Retheesh Kollerazhikathu; Venkitaraman, Sriram; Robert, Dennis; Narayanan, Sorna P; Mammen, Pratheesh C; Siddharth, Selva Raja; Kuriakose, Sekhar L