日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inflammation and Obesity Correlate in Pulmonary Hypertension but Are Associated with Diverging Outcomes

炎症和肥胖在肺动脉高压中存在相关性,但与不同的预后相关。

De Bie, Eckart; Correa-Jaque, Priscilla; Jones, Rowena; Bogaard, Harm J; Chan, Justine; Church, Colin; Coghlan, John G; Gaur, Akshay; Ghio, Stefano; Ghofrani, Hossein-Ardeschir; Goh, Ze Ming; Howard, Luke S; Humbert, Marc; Kovacs, Gabor; Lawrie, Allan; Lordan, James; Lin, Wei-Yu; Neelam-Naganathan, Dharshan; Newman, Joseph; Rhodes, Christopher J; Sheares, Karen; Sitbon, Olivier; Willis, Thomas W; Wort, Stephen J; Gräf, Stefan; Kiely, David G; Benza, Raymond L; Rothman, Alex; Wallace, Chris; Toshner, Mark

Enrichment of Cysteine S-palmitoylated Peptides Using Sodium Deoxycholate Acid Precipitation

利用脱氧胆酸钠酸沉淀法富集半胱氨酸S-棕榈酰化肽

Jensen, Peter T; Palmisano, Giuseppe; Rhodes, Christopher J; Larsen, Martin R

GLP-1 agonist, semaglutide use in acute pulmonary embolism recovery: a four-week proof-of-concept study including proteomic profiling

GLP-1受体激动剂索玛鲁肽在急性肺栓塞恢复中的应用:一项为期四周的概念验证研究,包括蛋白质组学分析

Samaranayake, Chinthaka B; Chen, Yen-Cheng; Fang, Min; Rhodes, Christopher J; Song, Shanshan; Sabrin, Farah; Ashek, Ali; Bonnici, Kathleen; Mukherjee, Bhashkar; Howard, Luke S; Pinguel, Joy; Rawal, Bhavin; Semple, Tom; Price, Laura C; Wort, S John; Rudd, Timothy; Zhao, Lan; McCabe, Colm

Consensus on the key characteristics of metabolism disruptors

关于代谢干扰物关键特征的共识

La Merrill, Michele A; Smith, Martyn T; McHale, Cliona M; Heindel, Jerrold J; Atlas, Ella; Cave, Matthew C; Collier, David; Guyton, Kathryn Z; Koliwad, Suneil; Nadal, Angel; Rhodes, Christopher J; Sargis, Robert M; Zeise, Lauren; Blumberg, Bruce

A cautionary note on the naive use of general-population biobanks to study pulmonary arterial hypertension, with a focus on Mendelian randomisation

关于简单地使用普通人群生物样本库研究肺动脉高压的警示,重点关注孟德尔随机化。

Woolf, Benjamin; De Bie, Eckart; McLaughlin, Vallerie; Gräf, Stefan; Toshner, Mark; Wilkins, Martin R; Rhodes, Christopher J; Burgess, Stephen

Clustering Patients with Pulmonary Hypertension Using the Plasma Proteome

利用血浆蛋白质组学对肺动脉高压患者进行聚类分析

Boucly, Athénaïs; Song, Shanshan; Keles, Merve; Wang, Dennis; Howard, Luke S; Humbert, Marc; Sitbon, Olivier; Lawrie, Allan; Thompson, A A Roger; Frank, Philipp; Kivimaki, Mika; Rhodes, Christopher J; Wilkins, Martin R

Endoglin as a BMP9 co-receptor in vascular endothelial cells: prodomain displacement and TGFBRII recruitment.

内皮糖蛋白作为血管内皮细胞中的 BMP9 共受体:前结构域置换和 TGFBRII 募集。

Guo Jingxu, Kostrzyńska Karolina, Kamzolas Ioannis, Yang Xudong, Thorikay Midory, De Bie Eckart, Jones Rowena J, Brownstein Adam, Long Lu, Rhodes Christopher J, Lawrie Allan, Wilkins Martin R, Groeneveld Esmee, Tong Zhen, Goumans Marie-José, Petsalaki Evangelia, Hong Jason, Toshner Mark R, Vidal-Puig Antonio, Arthur Helen M, Li Wei

GLP-1R/GCGR dual agonism dissipates hepatic steatosis to restore insulin sensitivity and rescue pancreatic β-cell function in obese male mice.

GLP-1R/GCGR 双重激动剂可消除肝脏脂肪变性,恢复肥胖雄性小鼠的胰岛素敏感性并挽救胰腺β细胞功能

Laker Rhianna C, Egolf Shaun, Will Sarah, Lantier Louise, McGuinness Owen P, Brown Charles, Bhagroo Nicholas, Oldham Stephanie, Kuszpit Kyle, Alfaro Alex, Li Xidan, Kang Taewook, Pellegrini Giovanni, Andréasson Anne-Christine, Kajani Sarina, Sitaula Sadichha, Larsen Martin R, Rhodes Christopher J

BMP9 knockout impairs pulmonary vessel muscularisation and confers aberrant tamoxifen sensitivity

BMP9基因敲除会损害肺血管肌化并导致对三苯氧胺的敏感性异常。

Dunmore, Benjamin J; Moore, Stephen; Jones, Rowena J; Hodgson, Joshua; Auckland, Kathryn; Southwood, Mark; Figg, Nichola; Kikuchi, Nobuhiro; Bennett, Martin; Lawrie, Allan; Rhodes, Christopher J; Toshner, Mark R; Gräf, Stefan; Li, Wei; Morrell, Nicholas W; Upton, Paul D

Specific loss of GIPR signaling in GABAergic neurons enhances GLP-1R agonist-induced body weight loss

GABA能神经元中GIPR信号传导的特异性缺失会增强GLP-1R激动剂引起的体重减轻。

Wean, Jordan; Kowalsky, Allison Ho; Laker, Rhianna; Will, Sarah; Drucker, Daniel J; Rhodes, Christopher J; Seeley, Randy J