日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

WNT7A-positive dendritic cytonemes control synaptogenesis in cortical neurons

WNT7A 阳性树突状细胞控制皮质神经元的突触形成

Thomas M Piers, Kevin Fang, Seema C Namboori, Corin Liddle, Sally Rogers, Akshay Bhinge, Richard Killick, Steffen Scholpp

Neurodegenerative Disease Associated Pathways in the Brains of Triple Transgenic Alzheimer's Model Mice Are Reversed Following Two Weeks of Peripheral Administration of Fasudil

两周外周给予法舒地尔后,三重转基因阿尔茨海默氏症模型小鼠大脑中神经退行性疾病相关通路发生逆转

Richard Killick, Christina Elliott, Elena Ribe, Martin Broadstock, Clive Ballard, Dag Aarsland, Gareth Williams

Masking the transmembrane region of the amyloid β precursor protein as a safe means to lower amyloid β production

掩盖淀粉样β蛋白前体的跨膜区是降低淀粉样β蛋白生成的安全方法

Ayesha Khan, Richard Killick, Daniel Wirth, Dominique Hoogland, Kalina Hristova, Jakob P Ulmschneider, Christopher R King, Martin B Ulmschneider

In vivo multi-parametric manganese-enhanced MRI for detecting amyloid plaques in rodent models of Alzheimer's disease

利用体内多参数锰增强磁共振成像技术检测阿尔茨海默病啮齿动物模型中的淀粉样斑块

Eugene Kim ,Davide Di Censo ,Mattia Baraldo ,Camilla Simmons ,Ilaria Rosa ,Karen Randall ,Clive Ballard ,Ben R Dickie ,Steven C R Williams ,Richard Killick ,Diana Cash

Bridging Integrator-1 protein loss in Alzheimer's disease promotes synaptic tau accumulation and disrupts tau release

阿尔茨海默病中的桥接整合子-1 蛋白丢失会促进突触 tau 积累并破坏 tau 释放

Elizabeth B Glennon, Dawn H-W Lau, Rebecca M C Gabriele, Matthew F Taylor, Claire Troakes, Sarah Opie-Martin, Christina Elliott, Richard Killick, Diane P Hanger, Beatriz G Perez-Nievas, Wendy Noble

A role for APP in Wnt signalling links synapse loss with β-amyloid production

APP 在 Wnt 信号传导中的作用将突触丢失与 β-淀粉样蛋白的产生联系起来

Christina Elliott, Ana I Rojo, Elena Ribe, Martin Broadstock, Weiming Xia, Peter Morin, Mikhail Semenov, George Baillie, Antonio Cuadrado, Raya Al-Shawi, Clive G Ballard, Paul Simons, Richard Killick

Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons

丛集素是人类 iPSC 衍生神经元中 β-淀粉样蛋白毒性的必要条件

Jacqueline P Robbins, Leo Perfect, Elena M Ribe, Marcello Maresca, Adrià Dangla-Valls, Evangeline M Foster, Richard Killick, Paulina Nowosiad, Matthew J Reid, Lucia Dutan Polit, Alejo J Nevado, Daniel Ebner, Mohammad Bohlooly-Y, Noel Buckley, Menelas N Pangalos, Jack Price, Simon Lovestone

Knockdown of the schizophrenia susceptibility gene TCF4 alters gene expression and proliferation of progenitor cells from the developing human neocortex

精神分裂症易感基因 TCF4 的敲除会改变正在发育的人类新皮质中的祖细胞的基因表达和增殖

Matthew J Hill, Richard Killick, Katherinne Navarrete, Aleksandra Maruszak, Gemma M McLaughlin, Brenda P Williams, Nicholas J Bray

An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba Dictyostelium discoideum

早老蛋白在社会变形虫盘基网柄菌多细胞发育中的祖先非蛋白水解作用

Marthe H R Ludtmann, Grant P Otto, Christina Schilde, Zhi-Hui Chen, Claire Y Allan, Selina Brace, Philip W Beesley, Alan R Kimmel, Paul Fisher, Richard Killick, Robin S B Williams

Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease

前列腺衍生的无菌 20 样激酶 (PSKs/TAOKs) 磷酸化 tau 蛋白,并在阿尔茨海默病中的缠结神经元中被激活

Ignatius A Tavares, Dona Touma, Steven Lynham, Claire Troakes, Megan Schober, Mirsada Causevic, Ritu Garg, Wendy Noble, Richard Killick, Istvan Bodi, Diane P Hanger, Jonathan D H Morris