日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

RNAi mediated silencing of STAT3/PD-L1 in tumor-associated immune cells induces robust anti-tumor effects in immunotherapy resistant tumors.

RNAi介导的肿瘤相关免疫细胞中STAT3/PD-L1的沉默可对免疫疗法耐药肿瘤产生强大的抗肿瘤作用

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2024.03.035
Ganesh Shanthi, Kim Min Ju, Lee Jenny, Feng Xudong, Ule Krisjanis, Mahan Amy, Krishnan Harini Sivagurunatha, Wang Zhe, Anzahaee Maryam Yahyaee, Singhal Garima, Korboukh Ilia, Lockridge Jennifer A, Sanftner Laura, Rijnbrand Rene, Abrams Marc, Brown Bob D
肿瘤
STAT3
发表日期：2024
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Inhibition of HBV replication by N-hydroxyisoquinolinedione and N-hydroxypyridinedione ribonuclease H inhibitors

N-羟基异喹啉二酮和N-羟基吡啶二酮核糖核酸酶H抑制剂对HBV复制的抑制作用

期刊:Antiviral Research
影响因子:4
doi:10.1016/j.antiviral.2019.02.005
Edwards, Tiffany C; Mani, Nagraj; Dorsey, Bruce; Kakarla, Ramesh; Rijnbrand, Rene; Sofia, Michael J; Tavis, John E
发表日期：2019
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Novel Ranking System for Identifying Efficacious Anti-Influenza Virus PB2 Inhibitors

一种用于识别高效抗流感病毒PB2抑制剂的新型排序系统

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00781-15
Tsai, Alice W; McNeil, Colleen F; Leeman, Joshua R; Bennett, Hamilton B; Nti-Addae, Kwame; Huang, Cassey; Germann, Ursula A; Byrn, Randal A; Berlioz-Seux, Francoise; Rijnbrand, Rene; Clark, Michael P; Charifson, Paul S; Jones, Steven M
微生物学
流感
发表日期：2015
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Genotypic and phenotypic analyses of hepatitis C virus variants observed in clinical studies of VX-222, a nonnucleoside NS5B polymerase inhibitor

对非核苷类NS5B聚合酶抑制剂VX-222临床研究中观察到的丙型肝炎病毒变异株进行基因型和表型分析

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.03052-14
Jiang, Min; Zhang, Eileen Z; Ardzinski, Andrzej; Tigges, Ann; Davis, Andrew; Sullivan, James C; Nelson, Michelle; Spanks, Joan; Dorrian, Jennifer; Nicolas, Olivier; Bartels, Doug J; Rao, B Govinda; Rijnbrand, Rene; Kieffer, Tara L
微生物学
肝炎
发表日期：2014
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Restoration of the activated Rig-I pathway in hepatitis C virus (HCV) replicon cells by HCV protease, polymerase, and NS5A inhibitors in vitro at clinically relevant concentrations

在体外，HCV蛋白酶、聚合酶和NS5A抑制剂在临床相关浓度下可恢复丙型肝炎病毒（HCV）复制子细胞中激活的Rig-I通路。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00399-13
Kalkeri, Gururaj; Lin, Chao; Gopilan, Jenna; Sloan, Kevin; Rijnbrand, Rene; Kwong, Ann D
Rig-I
信号转导
微生物学
细胞生物学
肝炎
发表日期：2013
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In vitro phenotypic characterization of hepatitis C virus NS3 protease variants observed in clinical studies of telaprevir

在特拉匹韦临床研究中观察到的丙型肝炎病毒NS3蛋白酶变体的体外表型特征

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01578-13
Jiang, Min; Mani, Nagraj; Lin, Chao; Ardzinski, Andrzej; Nelson, Michelle; Reagan, Dugan; Bartels, Doug; Zhou, Yi; Nicolas, Olivier; Rao, B Govinda; Müh, Ute; Hanzelka, Brian; Tigges, Ann; Rijnbrand, Rene; Kieffer, Tara L
微生物学
肝炎
发表日期：2013
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GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS

GB病毒B通过NS3/4A介导的接头蛋白MAVS的切割来破坏RIG-I信号传导。

期刊:Journal of Virology
影响因子:3.8
doi:10.1128/JVI.02076-06
Chen, Zihong; Benureau, Yann; Rijnbrand, Rene; Yi, Jianzhong; Wang, Ting; Warter, Lucile; Lanford, Robert E; Weinman, Steven A; Lemon, Stanley M; Martin, Annette; Li, Kui
微生物学
信号转导
MAVS
发表日期：2007
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Sequence requirements for viral RNA replication and VPg uridylylation directed by the internal cis-acting replication element (cre) of human rhinovirus type 14

人类鼻病毒14型内部顺式作用复制元件（cre）指导的病毒RNA复制和VPg尿苷酰化的序列要求

期刊:Journal of Virology
影响因子:3.8
doi:10.1128/jvi.76.15.7485-7494.2002
Yang, Yan; Rijnbrand, Rene; McKnight, Kevin L; Wimmer, Eckard; Paul, Aniko; Martin, Annette; Lemon, Stanley M
微生物学
发表日期：2002
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