Proteogenomic analysis in an early onset diffuse gastric cancer patient revealed alterations in PIK3R1, TP53, SMAD4 and a potential role of the PI3K-AKT and EGFR pathways: a case report
对一名早期弥漫型胃癌患者进行蛋白质基因组学分析,发现PIK3R1、TP53、SMAD4基因发生改变,并提示PI3K-AKT和EGFR通路可能发挥作用:病例报告
期刊:Journal of Gastrointestinal Oncology
影响因子:2
doi:10.21037/jgo-21-780
Cordova-Delgado, Miguel; Pinto, Mauricio P; Pizarro, Gonzalo; Koch, Elard; Vargas, Cristian; Hernández, Mauricio; Nourdin, Guillermo; Saldivia, Pablo; Rodriguez Z, Maria Paz; Berkovits, Alejandro; Manque, Patricio; Rios, Juvenal A; Garcia-Bloj, Benjamin; Garrido, Marcelo
胃癌
SMAD4
肿瘤
肿瘤免疫
信号转导
EGF
EGFR
P53
AKT