日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Delayed viral rebound post-ART interruption in infant macaques given SIV-specific neutralizing antibodies.

接受 SIV 特异性中和抗体治疗的幼年猕猴在 ART 中断后出现病毒反弹延迟。

Powers Jenna S, Bricker-Holt Katherine M, Williams Brianna, Obregon-Perko Veronica, Rivera Rodriguez Dormarie E, Sukkestad Sophia, Lopez Lakshita Lopez, Dashti Amir, Davis Kaleaha, Dinh Vinh, Fonseca Jairo A, Cotsonis George, Easley Kirk A, Levine Kate S, McManus Lindsay R, Blanc Ross, Heimann Ashley, Du Renguang, McNamara Ryan, Fennessey Christine M, Keele Brandon F, Mason Rosemarie D, Roederer Mario, Chahroudi Ann

IFN-γ- GranzymeB + Natural killer cells are induced by IV BCG vaccination and associated with protection against tuberculosis in rhesus macaques

IFN-γ-颗粒酶B+自然杀伤细胞可通过静脉注射卡介苗诱导产生,并与恒河猴的结核病保护作用相关。

Makatsa, Mohau S; Bishop, Emma; Bucsan, Allison N; Sutton, Matthew S; Lehman, Chelsea C; Robertson, Molly; Yu, Krystle K Q; Peters, Joshua M; Bryson, Bryan D; Roederer, Mario; Seder, Robert A; Darrah, Patricia A; Seshadri, Chetan

SARS-CoV-2 fusion-peptide-directed antibodies are elicited by natural infection and can mediate broad sarbecovirus neutralization.

自然感染可诱导产生针对 SARS-CoV-2 融合肽的抗体,并能介导广泛的沙贝病毒中和作用。

Roederer Alex L, Li Chia Jung, Lim Eunice, Cao Yi, Ronsard Larance, Lingwood Daniel, Canaday David H, Gravenstein Stefan, Balazs Alejandro B

Demonstration of in vivo efficacy, cryo-EM-epitope identification, and breadth of two anti-alphavirus bispecific single domain antibodies

体内疗效验证、冷冻电镜表位鉴定以及两种抗甲病毒双特异性单域抗体的广谱性

Gardner, Christina L; Pletnev, Sergei; Liu, Jinny L; Anderson, George P; Shriver-Lake, Lisa C; Bylund, Tatsiana; Green, Courtney; Stephens, Tyler; Sutton, Matthew S; Tsybovsky, Yaroslav; Roederer, Mario; Kwong, Peter D; Zhou, Tongqing; Goldman, Ellen R; Burke, Crystal W

A Novel Multimodal Deep Image Analysis Model for Predicting Extraction/Non-Extraction Decision

一种用于预测提取/非提取决策的新型多模态深度图像分析模型

Ahmad, Sunna Imtiaz; Olczyk, Jakub; Araújo, Adriel S; de Moura Medeiros, João Pedro; Teixeira, Vinicius C; Gomes, Carlos F A; Magnaguagno, Maurício Cecílio; Roederer, Quinn; Dutra, Vinicius; Conley, R Scott; Griebler, Dalvan; Eckert, George; Pinho, Márcio Sarroglia; Turkkahraman, Hakan

Antibody prophylaxis may mask subclinical SIV infections in macaques

抗体预防可能掩盖猕猴体内亚临床的SIV感染。

Gonelli, Christopher A; King, Hannah A D; Ko, SungYoul; Fennessey, Christine M; Iwamoto, Nami; Mason, Rosemarie D; Heimann, Ashley; Flebbe, Dillon R; Todd, John-Paul; Foulds, Kathryn E; Keele, Brandon F; Lifson, Jeffrey D; Koup, Richard A; Roederer, Mario

Adeno-associated viral delivery of Env-specific antibodies prevents SIV rebound after discontinuing antiretroviral therapy.

腺相关病毒递送 Env 特异性抗体可防止停止抗逆转录病毒治疗后 SIV 反弹

Klenchin Vadim A, Clark Natasha M, Keles Nida K, Capuano Saverio 3rd, Mason Rosemarie, Gao Guangping, Broman Aimee, Kose Emek, Immonen Taina T, Fennessey Christine M, Keele Brandon F, Lifson Jeffrey D, Roederer Mario, Gardner Matthew R, Evans David T

Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies

恒河猴广谱中和抗体识别HIV-1包膜V2顶端的结构和遗传基础

Ryan S Roark #   ,Rumi Habib # ,Jason Gorman ,Hui Li,Andrew Jesse Connell,Mattia Bonsignori,Yicheng Guo,Michael P Hogarty,Adam S Olia,Kirsten J Sowers,Baoshan Zhang,Frederic Bibollet-Ruche,Tatsiana Bylund,Sean Callaghan,John W Carey,Gabriele Cerutti ,Darcy R Harris,Wanting He,Emily Lewis,Tracy Liu,Rosemarie D Mason,Yujie Qiao,Younghoon Park,Juliette M Rando,Ajay Singh,Jeremy J Wolff,Q Paula Lei,Mark K Louder,Raiees Andrabi ,Nicole A Doria-Rose,Kevin O Saunders   ,Michael S Seaman,Barton F Haynes ,Daniel W Kulp ,John R Mascola,Mario Roederer,Theodore C Pierson,Zizhang Sheng,Beatrice H Hahn,George M Shaw,Peter D Kwong ,Lawrence Shapiro

SIV monoclonal antibody administration spanning treatment interruption in macaques delays viral rebound and selects escape variants

在猕猴治疗中断期间给予SIV单克隆抗体,可延缓病毒反弹并选择逃逸变异株。

King, Hannah A D; Brammer, Daniel; Lewitus, Eric; Fennessey, Christine M; Manalang, Kimberly M; Shrader, Hannah R; Andrew, Shayne; Kuri, Phillip; Lind, Matthew; Pham, Phuc; Sanders-Buell, Eric; Bai, Hongjun; Mason, Rosemarie; Song, Kaimei; McCarthy, Elizabeth; Helmold Hait, Sabrina; Todd, John-Paul; Pegu, Amarendra; Foulds, Kathryn E; Lifson, Jeffrey D; Keele, Brandon F; Rolland, Morgane; Roederer, Mario; Bolton, Diane L

Isolation and structure of broad SIV-neutralizing antibodies reveal a proximal helical MPER epitope recognized by a rhesus multi-donor class

广谱SIV中和抗体的分离和结构分析揭示了一种近端螺旋状MPER表位,该表位可被恒河猴多供体类SIV识别。

Jason Gorman,Renguang Du,Yen-Ting Lai,Mohammed S Ahmadi,Hannah A D King,Kaimei Song,Kimberly Manalang,Christopher A Gonelli,Chaim A Schramm,Cheng Cheng,Richard Nguyen,David Ambrozak,Aliaksandr Druz,Chen-Hsiang Shen,Yongping Yang,Daniel C Douek,Peter D Kwong,Mario Roederer,Rosemarie D Mason