Rousseau Frederic相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Phagocytes as plaque catalysts: Human macrophages generate seeding-competent Aβ42 fibrils with cross-seeding activity

吞噬细胞作为斑块催化剂：人巨噬细胞产生具有交叉播散活性的、可播散斑块的Aβ42原纤维

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2516774123

Konstantoulea, Katerina; Ramakers, Meine; Borrie, Sarah C; T'Syen, Dries; Moechars, Daan; Sliwinska, Malgorzata A; Pradhan, Brajabandhu; Albertini, Giulia; Baligács, Nóra; Tsaka, Grigoria; Houben, Bert; Fiers, Mark; Gallardo, Rodrigo; Dewilde, Maarten; Thal, Dietmar Rudolf; Willem, Michael; Neher, Jonas J; De Strooper, Bart; Rousseau, Frederic; Schymkowitz, Joost

免疫/内分泌

细胞生物学

发表日期：2026

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Conformation-specific monoclonal antibodies reveal early Tau structural intermediates in Alzheimer's disease

构象特异性单克隆抗体揭示阿尔茨海默病早期Tau蛋白结构中间体

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2026.111221

Tsaka, Grigoria; Pagès, Aida Montserrat; De Sousa, Cristiano Brás; Lammertyn, Jeroen; Walkiewicz, Grzegorz; Gomes, Luis Aragão; Imbrechts, Maya; Tops, Sophie; Kolla, Rajasekhar; Muwonge, Kevin; Vandenberghe, Rik; Vanhoorelbeke, Karen; von Arnim, Christine A F; Geukens, Nick; Rousseau, Frederic; Schymkowitz, Joost; Spasic, Dragana; Thal, Dietmar Rudolf; Thomas, Debby; Winderickx, Joris

单克隆抗体

阿尔茨海默症

发表日期：2026

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Composition and liquid-to-solid maturation of protein aggregates contribute to bacterial dormancy development and recovery

蛋白质聚集体的组成和液固转变过程有助于细菌休眠的发生和恢复。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-56387-8

Bollen, Celien; Louwagie, Sofie; Deroover, Femke; Duverger, Wouter; Khodaparast, Ladan; Khodaparast, Laleh; Hofkens, Dieter; Schymkowitz, Joost; Rousseau, Frederic; Dewachter, Liselot; Michiels, Jan

发表日期：2025

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Energetic profiling reveals thermodynamic principles underlying amyloid fibril maturation

能量分析揭示了淀粉样蛋白原纤维成熟的热力学原理

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-65035-0

Duran-Romaña, Ramon; Schymkowitz, Joost; Rousseau, Frederic; Louros, Nikolaos

发表日期：2025

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A versatile platform for combinatorial antibody library cloning and NGS-based quality control with high accuracy

一个用于组合抗体库克隆和基于NGS的质量控制的多功能平台，具有高精度

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkaf1001

Zhang, Zhongyao; D'Hondt, Simon; Van der Kant, Rob; Hermans, Guy; Geukens, Nick; Pinheiro, Vitor Bernardes; Schymkowitz, Joost; Rousseau, Frederic; Dewilde, Maarten

发表日期：2025

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Structural commonalities determined by physicochemical principles in the complex polymorphism of the amyloid state of proteins

蛋白质淀粉样蛋白状态复杂多态性中由物理化学原理决定的结构共性

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BCJ20240602

Errico, Silvia; Fani, Giulia; Ventura, Salvador; Schymkowitz, Joost; Rousseau, Frederic; Trovato, Antonio; Vendruscolo, Michele; Bemporad, Francesco; Chiti, Fabrizio

发表日期：2025

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Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity.

定向破坏 IL2 聚集和受体结合位点，可产生具有更高特异性和更强生产能力的定制生物制剂

期刊:Computational and Structural Biotechnology Journal

影响因子:4.1

doi:10.1016/j.csbj.2025.03.002

Dashwood Amy, Makuyana Ntombizodwa, van der Kant Rob, Ghodsinia Arman, Hernandez Alvaro R, Lienart Stephanie, Burton Oliver, Dooley James, Ali Magda, Kouser Lubna, Naranjo Francisco, Holt Matthew G, Rousseau Frederic, Schymkowitz Joost, Liston Adrian

发表日期：2025

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[(11)C]HSP990 PET as a translational tool to investigate the role of Hsp90 in tumours and support the development of Hsp90 therapeutics.

[(11)C]HSP990 PET 作为转化工具，用于研究 Hsp90 在肿瘤中的作用，并支持 Hsp90 疗法的开发。

期刊:EJNMMI Radiopharmacy and Chemistry

影响因子:3.3

doi:10.1186/s41181-025-00386-z

Cools Romy, Narykina Valeria, Vermeulen Koen, Mishra Sanket J, Blagg Brian S J, Derweduwe Marleen, De Smet Frederik, Ziani-Zeryouh Aaron, Riva Matteo, Coosemans An, Rousseau Frederic, Schymkowitz Joost, Bormans Guy

发表日期：2025

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Chemical Synthesis of Medin via a Removable Aggregation-Suppressing Linker

通过可移除的聚集抑制连接基化学合成美丁

期刊:Journal of Peptide Science

影响因子:1.8

doi:10.1002/psc.70041

De Vleeschouwer, Matthias; Pradhan, Brajabandhu; Rousseau, Frederic; Schymkowitz, Joost

发表日期：2025

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FoldX force field revisited, an improved version

FoldX力场的改进版本

doi:10.1093/bioinformatics/btaf064

Delgado, Javier; Reche, Raul; Cianferoni, Damiano; Orlando, Gabriele; van der Kant, Rob; Rousseau, Frederic; Schymkowitz, Joost; Serrano, Luis

发表日期：2025

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