日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tumor Heterogeneity Shapes Survival Dynamics in Drug-Treated Cells, Revealing Size-Drifting Subpopulations

肿瘤异质性影响药物治疗细胞的存活动态,揭示了大小漂移的亚群

Vangala, Venugopal; Chen, Yu-Chi; Dinavahi, Saketh S; Gowda, Krishne; Lone, Nazir A; Herlyn, Meenhard; Drabick, Joseph; Helm, Klaus; Zhu, Jiyue; Neves, Rogerio I; Sharma, Arun K; Berg, Arthur; Archetti, Marco; Amin, Shantu; Schell, Todd D; Robertson, Gavin P

Targeting WEE1/AKT Restores p53-Dependent Natural Killer-Cell Activation to Induce Immune Checkpoint Blockade Responses in "Cold" Melanoma

靶向 WEE1/AKT 可恢复 p53 依赖性自然杀伤细胞活化,从而诱导“冷”黑色素瘤中的免疫检查点阻断反应。

Saketh S Dinavahi ,Yu-Chi Chen ,Kishore Punnath ,Arthur Berg ,Meenhard Herlyn ,Momeneh Foroutan ,Nicholas D Huntington # ,Gavin P Robertson #

Targeting Protein Translation in Melanoma by Inhibiting EEF-2 Kinase Regulates Cholesterol Metabolism though SREBP2 to Inhibit Tumour Development

通过抑制EEF-2激酶靶向黑色素瘤中的蛋白质翻译,进而通过SREBP2调节胆固醇代谢,从而抑制肿瘤发展。

Dinavahi, Saketh S; Chen, Yu-Chi; Gowda, Raghavendra; Dhanyamraju, Pavan Kumar; Punnath, Kishore; Desai, Dhimant; Berg, Arthur; Kimball, Scot R; Amin, Shantu; Yang, Jin-Ming; Robertson, Gavin P

Activating Sphingosine-1-phospahte signaling in endothelial cells increases myosin light chain phosphorylation to decrease endothelial permeability thereby inhibiting cancer metastasis

激活内皮细胞中的鞘氨醇-1-磷酸信号可增加肌球蛋白轻链磷酸化,从而降低内皮通透性,从而抑制癌症转移

Yu-Chi Chen, Saketh S Dinavahi, Qilong Feng, Raghavendra Gowda, Srinivasa Ramisetti, Xinghai Xia, Kyle B LaPenna, Venkat R Chirasani, Sung Hyun Cho, Susan L Hafenstein, Madhu Babu Battu, Arthur Berg, Arun K Sharma, Tom Kirchhausen, Nikolay V Dokholyan, Shantu Amin, Pingnian He, Gavin P Robertson1

Development of a Novel Multi-Isoform ALDH Inhibitor Effective as an Antimelanoma Agent

开发一种新型多亚型 ALDH 抑制剂,可有效作为抗黑色素瘤药物

Saketh S Dinavahi, Raghavendra Gowda, Krishne Gowda, Christopher G Bazewicz, Venkat R Chirasani, Madhu Babu Battu, Arthur Berg, Nikolay V Dokholyan, Shantu Amin, Gavin P Robertson1

Aldehyde dehydrogenase in regulatory T-cell development, immunity and cancer

醛脱氢酶在调节性T细胞发育、免疫和癌症中的作用

Bazewicz, Christopher G; Dinavahi, Saketh S; Schell, Todd D; Robertson, Gavin P

Nanoliposomal delivery of cytosolic phospholipase A(2) inhibitor arachidonyl trimethyl ketone for melanoma treatment

利用纳米脂质体递送胞质磷脂酶A(2)抑制剂花生四烯酸三甲基酮治疗黑色素瘤

Gowda, Raghavendra; Dinavahi, Saketh S; Iyer, Soumya; Banerjee, Shubhadeep; Neves, Rogerio I; Pameijer, Colette R; Robertson, Gavin P

Moving Synergistically Acting Drug Combinations to the Clinic by Comparing Sequential versus Simultaneous Drug Administrations

通过比较序贯给药与同时给药,将具有协同作用的药物组合推向临床

Dinavahi, Saketh S; Noory, Mohammad A; Gowda, Raghavendra; Drabick, Joseph J; Berg, Arthur; Neves, Rogerio I; Robertson, Gavin P

Schweinfurthin natural products induce regression of murine melanoma and pair with anti-PD-1 therapy to facilitate durable tumor immunity

Schweinfurthin 天然产物可诱导小鼠黑色素瘤消退,并与抗 PD-1 疗法配合使用以促进持久的肿瘤免疫

Kathleen M Kokolus, Jeremy S Haley, Emily J Koubek, Raghavendra Gowda, Saketh S Dinavahi, Arati Sharma, David F Claxton, Klaus F Helm, Joseph J Drabick, Gavin P Robertson, Jeffrey D Neighbors, Raymond J Hohl, Todd D Schell

Improving pharmacological targeting of AKT in melanoma

改善黑色素瘤中 AKT 的药物靶向性

Omer F Kuzu, Raghavendra Gowda, Arati Sharma, Mohammad A Noory, Saketh S Dinavahi, Gregory Kardos, Joseph J Drabick, Gavin P Robertson