日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting WEE1/AKT Restores p53-Dependent Natural Killer-Cell Activation to Induce Immune Checkpoint Blockade Responses in "Cold" Melanoma

靶向 WEE1/AKT 可恢复 p53 依赖性自然杀伤细胞活化,从而诱导“冷”黑色素瘤中的免疫检查点阻断反应。

Saketh S Dinavahi ,Yu-Chi Chen ,Kishore Punnath ,Arthur Berg ,Meenhard Herlyn ,Momeneh Foroutan ,Nicholas D Huntington # ,Gavin P Robertson #

Activating Sphingosine-1-phospahte signaling in endothelial cells increases myosin light chain phosphorylation to decrease endothelial permeability thereby inhibiting cancer metastasis

激活内皮细胞中的鞘氨醇-1-磷酸信号可增加肌球蛋白轻链磷酸化,从而降低内皮通透性,从而抑制癌症转移

Yu-Chi Chen, Saketh S Dinavahi, Qilong Feng, Raghavendra Gowda, Srinivasa Ramisetti, Xinghai Xia, Kyle B LaPenna, Venkat R Chirasani, Sung Hyun Cho, Susan L Hafenstein, Madhu Babu Battu, Arthur Berg, Arun K Sharma, Tom Kirchhausen, Nikolay V Dokholyan, Shantu Amin, Pingnian He, Gavin P Robertson1

Development of a Novel Multi-Isoform ALDH Inhibitor Effective as an Antimelanoma Agent

开发一种新型多亚型 ALDH 抑制剂,可有效作为抗黑色素瘤药物

Saketh S Dinavahi, Raghavendra Gowda, Krishne Gowda, Christopher G Bazewicz, Venkat R Chirasani, Madhu Babu Battu, Arthur Berg, Nikolay V Dokholyan, Shantu Amin, Gavin P Robertson1

Schweinfurthin natural products induce regression of murine melanoma and pair with anti-PD-1 therapy to facilitate durable tumor immunity

Schweinfurthin 天然产物可诱导小鼠黑色素瘤消退,并与抗 PD-1 疗法配合使用以促进持久的肿瘤免疫

Kathleen M Kokolus, Jeremy S Haley, Emily J Koubek, Raghavendra Gowda, Saketh S Dinavahi, Arati Sharma, David F Claxton, Klaus F Helm, Joseph J Drabick, Gavin P Robertson, Jeffrey D Neighbors, Raymond J Hohl, Todd D Schell

Improving pharmacological targeting of AKT in melanoma

改善黑色素瘤中 AKT 的药物靶向性

Omer F Kuzu, Raghavendra Gowda, Arati Sharma, Mohammad A Noory, Saketh S Dinavahi, Gregory Kardos, Joseph J Drabick, Gavin P Robertson