日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Experimental evidence that readily diffusible forms of Aβ from Alzheimer's disease brain have seeding activity.

实验证据表明，阿尔茨海默病患者大脑中易扩散的 Aβ 形式具有播种活性

期刊:Acta Neuropathologica Communications
影响因子:5.7
doi:10.1186/s40478-025-02032-w
Song Simin, Liu Qianmin, Chen Ruixiang, Chen Ping, Tao Min, Li Siyao, Guo Liping, Zhu Xixi, Liu Yan, Liu Lu, Sasaguri Hiroki, Saito Takashi, Saido Takaomi C, Walsh Dominic M, Zhang Zhangjin, Hong Wei
神经科学
发表日期：2025
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High-Fat Diet-Induced Excessive Accumulation of Cerebral Cholesterol Esters and Microglial Dysfunction Exacerbate Alzheimer's Disease Pathology in APP(NL-G-F) mice.

高脂饮食诱导的脑胆固醇酯过度积累和小胶质细胞功能障碍加剧了 APP(NL-GF) 小鼠的阿尔茨海默病病理

期刊:Molecular Neurobiology
影响因子:4.3
doi:10.1007/s12035-025-05052-8
Yang Shuhan, Miyazaki Hirofumi, Wannakul Tunyanat, Amo Eiko, Saido Takaomi, Saito Takashi, Sasaguri Hiroki, Maekawa Motoko, Owada Yuji
细胞生物学
发表日期：2025
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The Role of Neprilysin and Insulin-Degrading Enzyme in the Etiology of Sporadic Alzheimer's Disease.

脑啡肽酶和胰岛素降解酶在散发性阿尔茨海默病病因学中的作用

期刊:Journal of Neuroscience
影响因子:4
doi:10.1523/JNEUROSCI.2152-24.2025
Morito Takahiro, Hashimoto Shoko, Takamura Risa, Watamura Naoto, Kakiya Naomasa, Fujioka Ryo, Mihara Naomi, Sekiguchi Misaki, Watanabe-Iwata Kaori, Kamano Naoko, Qi Mohan, Matsuba Yukio, Tsubuki Satoshi, Saito Takashi, Iwata Nobuhisa, Sasaguri Hiroki, Saido Takaomi C
代谢
发表日期：2025
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APOE4-APP interactions exert early influences on cerebrovascular structure and function: implications for Alzheimer's disease.

APOE4-APP 相互作用对脑血管结构和功能产生早期影响：对阿尔茨海默病的影响。

期刊:Frontiers in Neuroscience
影响因子:3.2
doi:10.3389/fnins.2025.1629830
Guo Lanboling, Gaunt Jessica R, Cheah Calvin Chee Hoe, Chen Albert I, Claudine Stephanie, Dawe Gavin S, Goh Eyleen Lay Keow, Kho Sok-Hong, Kumar Pawan, Lim Grace G Y, Lim Kah Leong, Lim Yun-An, Saido Takaomi C, Saito Takashi, Sasaguri Hiroki, Sng Judy C G, Yeap Yee Jie, Yip Alaric K K, Zainolabidin Norliyana, Ch'ng Toh Hean, Augustine George J
阿尔茨海默症
神经科学
APP
APOE
发表日期：2025
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A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury

微管稳定剂可改善小鼠重复性创伤性脑损伤模型中的蛋白质病理发生和神经退行性变。

期刊:Science Translational Medicine
影响因子:
doi:10.1126/scitranslmed.abo6889
Zhao, Xinyi; Zeng, Wen; Xu, Hong; Sun, Zihan; Hu, Yingxin; Peng, Beibei; McBride, Jennifer D; Duan, Jiangtao; Deng, Juan; Zhang, Bin; Kim, Soo-Jung; Zoll, Bryan; Saito, Takashi; Sasaguri, Hiroki; Saido, Takaomi C; Ballatore, Carlo; Yao, Haishan; Wang, Zhaoyin; Trojanowski, John Q; Brunden, Kurt R; Lee, Virginia M-Y; He, Zhuohao
神经科学
发表日期：2023
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Does corporate social responsibility impact equity risk? International evidence

企业社会责任是否会影响股权风险？国际证据

期刊:EMBO Journal
影响因子:8.3
doi:10.15252/embj.201797397
Sasaguri, Hiroki; Nilsson, Per; Hashimoto, Shoko; Nagata, Kenichi; Saito, Takashi; De Strooper, Bart; Hardy, John; Vassar, Robert; Winblad, Bengt; Saido, Takaomi C; Monti, Alice; Pattitoni, Pierpaolo; Petracci, Barbara; Randl, Otto
发表日期：2022
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Recent Advances in the Modeling of Alzheimer's Disease

阿尔茨海默病建模的最新进展

期刊:Frontiers in Neuroscience
影响因子:
doi:10.3389/fnins.2022.807473
Sasaguri, Hiroki; Hashimoto, Shoko; Watamura, Naoto; Sato, Kaori; Takamura, Risa; Nagata, Kenichi; Tsubuki, Satoshi; Ohshima, Toshio; Yoshiki, Atsushi; Sato, Kenya; Kumita, Wakako; Sasaki, Erika; Kitazume, Shinobu; Nilsson, Per; Winblad, Bengt; Saito, Takashi; Iwata, Nobuhisa; Saido, Takaomi C
阿尔茨海默症
发表日期：2022
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Early Identification of Alzheimer's Disease in Mouse Models: Application of Deep Neural Network Algorithm to Cognitive Behavioral Parameters

利用深度神经网络算法在小鼠模型中早期识别阿尔茨海默病：认知行为参数的应用

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2021.102198
Sutoko, Stephanie; Masuda, Akira; Kandori, Akihiko; Sasaguri, Hiroki; Saito, Takashi; Saido, Takaomi C; Funane, Tsukasa
Mouse
发表日期：2021
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A third-generation mouse model of Alzheimer's disease shows early and increased cored plaque pathology composed of wild-type human amyloid β peptide

第三代阿尔茨海默病小鼠模型显示出早期且增加的由野生型人类β淀粉样蛋白肽组成的核心斑块病理。

期刊:Journal of Biological Chemistry
影响因子:
doi:10.1016/j.jbc.2021.101004
Sato, Kaori; Watamura, Naoto; Fujioka, Ryo; Mihira, Naomi; Sekiguchi, Misaki; Nagata, Kenichi; Ohshima, Toshio; Saito, Takashi; Saido, Takaomi C; Sasaguri, Hiroki
阿尔茨海默症
发表日期：2021
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The extreme N-terminus of TDP-43 mediates the cytoplasmic aggregation of TDP-43 and associated toxicity in vivo

TDP-43 的 N 端极度区域介导 TDP-43 在细胞质中的聚集以及相关的体内毒性。

期刊:Brain Research
影响因子:2.6
doi:10.1016/j.brainres.2016.04.069
Sasaguri, Hiroki; Chew, Jeannie; Xu, Ya-Fei; Gendron, Tania F; Garrett, Aliesha; Lee, Chris W; Jansen-West, Karen; Bauer, Peter O; Perkerson, Emilie A; Tong, Jimei; Stetler, Caroline; Zhang, Yong-Jie
细胞生物学
毒理研究
发表日期：2016
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