日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human broadly neutralizing influenza B virus antibodies recognizing hemagglutinin computationally optimized broadly reactive antigens

人类广谱中和流感B病毒抗体,识别血凝素,经计算机优化的广谱反应性抗原

Campos Mota, Yailin; Dzimianski, John V; Lopez, Mariana; Richardson, Robert A; Ross, Ted M; Kunkel, Ian J A; O'Rourke, Sara M; Balasco Serrão, Vitor Hugo; DuBois, Rebecca M; Sautto, Giuseppe A

Extended Heterosubtypic Neutralization and Preclinical Model In Vivo Protection from Clade 2.3.4.4b H5 Influenza Virus Infection by Broadly Neutralizing Antibodies

广谱中和抗体对2.3.4.4b分支H5流感病毒感染的扩展异亚型中和作用及临床前模型体内保护作用

Caputo, Valeria; Libera, Martina; Campos Mota, Yailin; Nagashima, Kaito; Moreno Martin, Ana Maria; Trombetta, Claudia Maria; Dapporto, Francesca; Mousa, Jarrod J; Montomoli, Emanuele; Sautto, Giuseppe A; Diotti, Roberta Antonia

Delineation of the antibody light chain biases and kinetics following primary and secondary influenza virus infections of ferrets

雪貂初次和二次流感病毒感染后抗体轻链偏向性和动力学的阐明

Richardson, Robert A; Rowe, Thomas; Kirchenbaum, Greg A; Zhang, Xiaojian; Shi, Hua; Sautto, Giuseppe A; Ross, Ted M

Generation of antigen-specific paired-chain antibodies using large language models

利用大型语言模型生成抗原特异性双链抗体

Wasdin, Perry T; Johnson, Nicole V; Janke, Alexis K; Held, Sofia; Marinov, Toma M; Jordaan, Gwen; Gillespie, Rebecca A; Vandenabeele, Léna; Pantouli, Fani; Powers, Olivia C; Vukovich, Matthew J; Holt, Clinton M; Kim, Jeongryeol; Hansman, Grant; Logue, Jennifer; Chu, Helen Y; Andrews, Sarah F; Kanekiyo, Masaru; Sautto, Giuseppe A; Ross, Ted M; Sheward, Daniel J; McLellan, Jason S; Abu-Shmais, Alexandra A; Georgiev, Ivelin S

Novel Skp1 inhibitor has potent preclinical efficacy against castration-resistant prostate cancer

新型Skp1抑制剂对去势抵抗性前列腺癌具有显著的临床前疗效

Li, Xin; Mamouni, Kenza; Zhao, Rui; Bai, Lijuan; Chen, Yanhua; Wu, Yifei; Xie, Zhong-Ru; Sautto, Giuseppe A; Liu, Degang; Bowen, Nathan J; Danaher, Alira; Li, Dehong; Cook, Nicholas; Grayson, Skylar; Zhu, Jedidiah; Coleman, Ilsa M; Nelson, Peter S; Bao, Qichao; Zhou, Jia; Osunkoya, Adeboye O; Kucuk, Omer; Gera, Lajos; Wu, Daqing

Gene discovery and expression analysis of the B cell receptor repertoire in the domestic ferret model

家养雪貂模型中B细胞受体库的基因发现和表达分析

Luke S Hebert,Whitney Pickens,Ed Satterwhite,Gabriel B Soto,Franziska M Pflaum,Michael Zhan,M Anthony Moody,Jessica Kain,Greg A Kirchenbaum,James A Ferguson,Stephanie N Langel,Ted M Ross,Giuseppe A Sautto,Naoko Uno,Robert A Richardson,George Georgiou,Jason J Lavinder,Gregory C Ippolito,Allison Seeger

Corrigendum to "Leveraging large language models to predict antibody biological activity against influenza A hemagglutinin" [Comput Struct Biotechnol J 27 (2025) 1286-1295]

对“利用大型语言模型预测针对甲型流感血凝素的抗体生物活性”的更正[Comput Struct Biotechnol J 27 (2025) 1286-1295]

Barkan, Ella; Siddiqui, Ibrahim; Cheng, Kevin J; Golts, Alex; Shoshan, Yoel; Weber, Jeffrey K; Mota, Yailin Campos; Ozery-Flato, Michal; Sautto, Giuseppe A

Leveraging large language models to predict antibody biological activity against influenza A hemagglutinin

利用大型语言模型预测针对甲型流感病毒血凝素的抗体生物活性

Barkan, Ella; Siddiqui, Ibrahim; Cheng, Kevin J; Golts, Alex; Shoshan, Yoel; Weber, Jeffrey K; Campos Mota, Yailin; Ozery-Flato, Michal; Sautto, Giuseppe A

Assessing the structural boundaries of broadly reactive antibody interactions with diverse H3 influenza hemagglutinin proteins

评估广谱反应性抗体与多种H3流感血凝素蛋白相互作用的结构边界

Dzimianski, John V; Nagashima, Kaito A; Cruz, Joseph M; Sautto, Giuseppe A; O'Rourke, Sara M; Serrão, Vitor H B; Ross, Ted M; Mousa, Jarrod J; DuBois, Rebecca M

Generation of antigen-specific paired chain antibody sequences using large language models

使用大型语言模型生成抗原特异性双链抗体序列

Perry T Wasdin, Nicole V Johnson, Alexis K Janke, Sofia Held, Toma M Marinov, Gwen Jordaan, Léna Vandenabeele, Fani Pantouli, Rebecca A Gillespie, Matthew J Vukovich, Clinton M Holt, Jeongryeol Kim, Grant Hansman, Jennifer Logue, Helen Y Chu, Sarah F Andrews, Masaru Kanekiyo, Giuseppe A Sautto, Ted