Pharmacological Analysis of NLRP3 Inflammasome Inhibitor Sodium [(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl][(1-methyl-1H-pyrazol-4-yl)({[(2S)-oxolan-2-yl]methyl})sulfamoyl]azanide in Cellular and Mouse Models of Inflammation Provides a Translational Framework.

在细胞和小鼠炎症模型中对 NLRP3 炎症小体抑制剂钠 [(1,2,3,5,6,7-六氢-s-茚满-4-基)氨基甲酰基][(1-甲基-1H-吡唑-4-基)({[(2S)-氧杂环戊烷-2-基]甲基})磺酰胺酰基]氮化物进行药理学分析，为转化应用提供了框架