Scott D Cramer相关文献与解析，生知库 | 链接生命科学的每一步

MAP3K7 Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of CHD1

MAP3K7 缺失会增强雄激素信号，并与 CHD1 缺失共同导致前列腺癌复发风险

Lauren K Jillson, Leah C Rider #, Lindsey U Rodrigues #, Lina Romero, Anis Karimpour-Fard, Cera Nieto, Claire Gillette, Kathleen Torkko, Etienne Danis, Elizabeth E Smith, Rosalie Nolley, Donna M Peehl, M Scott Lucia, James C Costello, Scott D Cramer

信号转导

MAP3K7 and CHD1 Are Novel Mediators of Resistance to Oncolytic Vesicular Stomatitis Virus in Prostate Cancer Cells

MAP3K7 和 CHD1 是前列腺癌细胞对溶瘤水泡性口炎病毒产生抗性的新型介质

期刊:Molecular Therapy-Oncolytics

影响因子:5.3

doi:10.1016/j.omto.2020.05.004

Robert S Bayne, Shelby Puckett, Lindsey Ulkus Rodrigues, Scott D Cramer, Jingyun Lee, Cristina M Furdui, Jeff W Chou, Lance D Miller, David A Ornelles, Douglas S Lyles

Loss of MAP3K7 Sensitizes Prostate Cancer Cells to CDK1/2 Inhibition and DNA Damage by Disrupting Homologous Recombination

MAP3K7 缺失通过破坏同源重组使前列腺癌细胞对 CDK1/2 抑制和 DNA 损伤敏感

期刊:Molecular Cancer Research

影响因子:4.1

doi:10.1158/1541-7786.MCR-18-1335

Satoshi Washino, Leah C Rider, Lina Romero, Lauren K Jillson, Trisiani Affandi, Angela M Ohm, Elaine T Lam, Mary E Reyland, James C Costello #, Scott D Cramer #

Prostatic adenocarcinoma CNS parenchymal and dural metastases: alterations in ERG, CHD1 and MAP3K7 expression

前列腺腺癌中枢神经系统实质和硬脑膜转移：ERG、CHD1 和 MAP3K7 表达的改变

期刊:Journal of Neuro-Oncology

影响因子:3.2

doi:10.1007/s11060-019-03099-x

D Ryan Ormond, B K Kleinschmidt-DeMasters, Daniel Cavalcante, Elizabeth E Smith, Scott D Cramer, M Scott Lucia

CD38 Inhibits Prostate Cancer Metabolism and Proliferation by Reducing Cellular NAD+ Pools

CD38 通过减少细胞 NAD+ 池来抑制前列腺癌代谢和增殖

期刊:Molecular Cancer Research

影响因子:4.1

doi:10.1158/1541-7786.MCR-17-0526

Jeffrey P Chmielewski, Sarah C Bowlby, Frances B Wheeler, Lihong Shi, Guangchao Sui, Amanda L Davis, Timothy D Howard, Ralph B D'Agostino Jr, Lance D Miller, S Joseph Sirintrapun, Scott D Cramer, Steven J Kridel

The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis

自噬机制控制细胞死亡在凋亡和坏死性凋亡之间切换

期刊:Developmental Cell

影响因子:10.7

doi:10.1016/j.devcel.2016.04.018

Megan L Goodall, Brent E Fitzwalter, Shadi Zahedi, Min Wu, Diego Rodriguez, Jean M Mulcahy-Levy, Douglas R Green, Michael Morgan, Scott D Cramer, Andrew Thorburn

Silibinin prevents prostate cancer cell-mediated differentiation of naïve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF β2

水飞蓟宾通过靶向 TGF β2 阻止前列腺癌细胞介导的幼稚成纤维细胞分化为癌症相关成纤维细胞表型

期刊:Molecular Carcinogenesis

影响因子:3

doi:10.1002/mc.22135

Harold J Ting, Gagan Deep, Anil K Jain, Adela Cimic, Joseph Sirintrapun, Lina M Romero, Scott D Cramer, Chapla Agarwal, Rajesh Agarwal

Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts

抑制脂质氧化可增加葡萄糖代谢并增强前列腺癌小鼠异种移植中 2-脱氧-2-[(18)F]氟-D-葡萄糖的摄取

期刊:Molecular Imaging and Biology

影响因子:3

doi:10.1007/s11307-014-0814-4

Isabel R Schlaepfer, L Michael Glodé, Carolyn A Hitz, Colton T Pac, Kristen E Boyle, Paul Maroni, Gagan Deep, Rajesh Agarwal, Scott M Lucia, Scott D Cramer, Natalie J Serkova, Robert H Eckel

Lipid catabolism via CPT1 as a therapeutic target for prostate cancer

通过 CPT1 进行脂质分解代谢作为前列腺癌的治疗靶点

期刊:Molecular Cancer Therapeutics

影响因子:5.3

doi:10.1158/1535-7163.MCT-14-0183

Isabel R Schlaepfer, Leah Rider, Lindsey Ulkus Rodrigues, Miguel A Gijón, Colton T Pac, Lina Romero, Adela Cimic, S Joseph Sirintrapun, L Michael Glodé, Robert H Eckel, Scott D Cramer

MIRO2 Regulates Prostate Cancer Cell Growth via GCN1-Dependent Stress Signaling

MIRO2通过GCN1依赖性应激信号调控前列腺癌细胞生长

MAP3K7 Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of CHD1

MAP3K7 缺失会增强雄激素信号，并与 CHD1 缺失共同导致前列腺癌复发风险

MAP3K7 and CHD1 Are Novel Mediators of Resistance to Oncolytic Vesicular Stomatitis Virus in Prostate Cancer Cells

MAP3K7 和 CHD1 是前列腺癌细胞对溶瘤水泡性口炎病毒产生抗性的新型介质

Loss of MAP3K7 Sensitizes Prostate Cancer Cells to CDK1/2 Inhibition and DNA Damage by Disrupting Homologous Recombination

MAP3K7 缺失通过破坏同源重组使前列腺癌细胞对 CDK1/2 抑制和 DNA 损伤敏感

Prostatic adenocarcinoma CNS parenchymal and dural metastases: alterations in ERG, CHD1 and MAP3K7 expression

前列腺腺癌中枢神经系统实质和硬脑膜转移：ERG、CHD1 和 MAP3K7 表达的改变

CD38 Inhibits Prostate Cancer Metabolism and Proliferation by Reducing Cellular NAD+ Pools

CD38 通过减少细胞 NAD+ 池来抑制前列腺癌代谢和增殖

The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis

自噬机制控制细胞死亡在凋亡和坏死性凋亡之间切换

Silibinin prevents prostate cancer cell-mediated differentiation of naïve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF β2

水飞蓟宾通过靶向 TGF β2 阻止前列腺癌细胞介导的幼稚成纤维细胞分化为癌症相关成纤维细胞表型

Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts

抑制脂质氧化可增加葡萄糖代谢并增强前列腺癌小鼠异种移植中 2-脱氧-2-[(18)F]氟-D-葡萄糖的摄取

Lipid catabolism via CPT1 as a therapeutic target for prostate cancer

通过 CPT1 进行脂质分解代谢作为前列腺癌的治疗靶点