日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Midostaurin response in AML is shaped by a progenitor-like cell state selectively targeted by SMAC mimetics

急性髓系白血病中米哚妥林的反应受SMAC模拟物选择性靶向的祖细胞样细胞状态的影响。

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-026-01363-8
Struyf, Nona; Gezelius, Henrik; Lundmark, Anders; Barizza, Chiara; Ploeger, Hidde; Rico Pizarro, Lucia; Vesterlund, Mattias; Mermelekas, Georgios; Österroos, Albin; Bohlin, Anna; Bengtzén, Sofia; Hamberg Levedahl, Kerstin; Jafari, Rozbeh; Orre, Lukas M; Lehtiö, Janne; Östling, Päivi; Seashore-Ludlow, Brinton; Nordlund, Jessica; Lehmann, Sören; Kallioniemi, Olli; Erkers, Tom
白血病
细胞生物学
发表日期：2026
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Experimental and machine learning-based exploration of repurposed drugs reveals chemical features underlying phospholipidosis

通过实验和机器学习方法对现有药物进行探索，揭示了磷脂沉积症的潜在化学特征。

期刊:Patterns
影响因子:7.4
doi:10.1016/j.patter.2025.101453
Kuzikov, Maria; Kalman, Adelinn; Karki, Reagon; Reinshagen, Jeanette; Huchting, Johanna; Qian, Kun; Axelsson, Hanna; Tampere, Marianna; Östling, Päivi; Seashore-Ludlow, Brinton; Gadiya, Yojana; Gribbon, Philip; Zaliani, Andrea
发表日期：2026
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Protocol for culture, drug treatment, and dissociation of patient-derived 3D ovarian cancer microspheroids for flow cytometry

用于流式细胞术的患者来源三维卵巢癌微球的培养、药物处理和解离方案

期刊:STAR Protocols
影响因子:1.3
doi:10.1016/j.xpro.2026.104480
Haffa, Mariam; Juhani, Karolina; Gudoityte, Greta; Hutyra-Gram Ötvös, Rita; Wallin, Emelie; Kallioniemi, Olli-Pekka; Fernebro, Josefin; Joneborg, Ulrika; Seashore-Ludlow, Brinton
肿瘤
肿瘤免疫
FCM
卵巢癌
细胞生物学
发表日期：2026
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Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth.

靶向抑制 WIP1 和组蛋白 H3K27 去甲基化酶活性可协同抑制神经母细胞瘤的生长

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-07658-1
Treis Diana, Lundberg Kristina Ihrmark, Bell Nicola, Polychronopoulos Panagiotis Alkinoos, Tümmler Conny, à kerlund Emma, Aliverti Stefania, Lilienthal Ingrid, Pepich Adena, Seashore-Ludlow Brinton, Sakaguchi Kazuyasu, Kogner Per, Johnsen John Inge, Wickström Malin
神经科学
H3
发表日期：2025
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Evaluating feature extraction in ovarian cancer cell line co-cultures using deep neural networks.

利用深度神经网络评估卵巢癌细胞系共培养中的特征提取

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-025-07766-w
Sharma Osheen, Gudoityte Greta, Minozada Rezan, Kallioniemi Olli P, Turkki Riku, Paavolainen Lassi, Seashore-Ludlow Brinton
神经科学
细胞生物学
卵巢癌
肿瘤免疫
发表日期：2025
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Low levels of DNA repair enzyme NEIL2 May exacerbate inflammation and genomic damage in subjects with stable COPD and during severe exacerbations

DNA修复酶NEIL2水平过低可能会加剧稳定期慢性阻塞性肺病患者以及重度急性加重期患者的炎症和基因组损伤。

期刊:Respiratory Research
影响因子:5
doi:10.1186/s12931-025-03251-4
Cardenas, Victor J Jr; Seashore, Justin B; Tapryal, Nisha; Ameri, Moe; Rivera, Rosalinda; Sharma, Kabir; Hazra, Tapas
炎症/感染
炎症
IL2
发表日期：2025
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Functional-proteomics-based investigation of the cellular response to farnesyltransferase inhibition in lung cancer

基于功能蛋白质组学的研究肺癌细胞对法呢基转移酶抑制的反应

期刊:iScience
影响因子:4.6
doi:10.1016/j.isci.2025.111864
Yanbo Pan, Olena Berkovska, Soumitra Marathe, Georgios Mermelekas, Greta Gudoityte, Amare D Wolide, Taner Arslan, Brinton Seashore-Ludlow, Janne Lehtiö, Lukas M Orre
免疫
细胞生物学
肺癌
肿瘤细胞
发表日期：2025
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Systematic profiling of cancer-fibroblast interactions reveals drug combinations in ovarian cancer

对癌细胞-成纤维细胞相互作用的系统性分析揭示了卵巢癌的药物组合。

期刊:Molecular Oncology
影响因子:4.5
doi:10.1002/1878-0261.70051
Gudoityte, Greta; Sharma, Osheen; Leuenberger, Laura; Wallin, Emelie; Fernebro, Josefin; Östling, Päivi; Bergström, Rebecka; Lindberg, Johan; Joneborg, Ulrika; Kallioniemi, Olli; Seashore-Ludlow, Brinton
成纤维细胞
肿瘤
肿瘤免疫
卵巢癌
细胞生物学
发表日期：2025
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Ex Vivo Drug Sensitivity of Pleural Effusion-Derived Cells from Lung Cancer and Pleural Mesothelioma Patients Is Linked to Clinical Response

肺癌和胸膜间皮瘤患者胸腔积液来源细胞的体外药物敏感性与临床反应相关

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers17142363
Hutyra-Gram Ötvös, Rita; Krynska, Hanna; Gudoityte, Greta; Skribek, Marcus; Oniscu, Anca; Berkovska, Olena; Strauß, Katharina; Zipprick, Jenny; Tamborero, David; Alexeyenko, Andrey; Gad, Annica Karin Britt; Seashore-Ludlow, Brinton; Dobra, Katalin
肺癌
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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From library to landscape: integrative annotation workflows for compound libraries in drug repurposing

从库到景观：药物重定位中化合物库的整合注释工作流程

期刊:Database-The Journal of Biological Databases and Curation
影响因子:3.6
doi:10.1093/database/baaf081
Reinshagen, Jeanette; Seashore-Ludlow, Brinton; Gadiya, Yojana; Gustavsson, Anna-Lena; Tanoli, Ziaurrehman; Aittokallio, Tero; Huchting, Johanna; Jenmalm-Jensen, Annika; Gribbon, Philip; Zaliani, Andrea; Ballante, Flavio
发表日期：2025
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