日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery and Characterization of Divarasib (GDC-6036), a Potent Covalent Inhibitor of KRAS G12C.

Divarasib (GDC-6036) 的发现和表征,一种强效的 KRAS G12C 共价抑制剂。

Endres Nicholas F, Do Steven, Mroue Rana, Terrett Jack A, Saabye Matt, Oh Angela, Hunsaker Thomas, Chan Emily, Tran John C, Nguyen Lan K, Lian Qihui, Ma Taylur P, Garner Thomas, Gerosa Luca, Beresini Maureen, Boudreau Aaron, Bronner Sarah M, Cyr Patrick, Ishisoko Noriko, Izrayelit Yevgeniy, Jiang Fan, Kellar Terry, La Hank, Labadie Sharada, Lardy Matthew, Liu Liling, Liu Wendy, Miller Sarah, Rudolph Joachim, Plise Emile, Sellers Benjamin D, Shao Cheng, Wang Weiru, Wang Yanguang, Wei Wentao, Wong Susan, Yu Christine, Yu Kebing, Yuen Po-Wai, Zang Richard, Zhang Chenghong, Zhou Yuhui, Zhu Xiaoyu, Quinn John G, Ye Xin, Kiefer James R, Mao Jialin, Evangelista Marie, Merchant Mark, Landry Matthew L, Malhotra Sushant, Purkey Hans E

Utilizing Molecular Simulations to Examine Nanosuspension Stability

利用分子模拟研究纳米悬浮液的稳定性

Latham, Andrew P; Levy, Elizabeth S; Sellers, Benjamin D; Leung, Dennis H

GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models.

GluN2A NMDA 受体增强可改善 Dravet 综合征和阿尔茨海默病模型中的脑振荡、同步性和认知功能

Hanson Jesse E, Ma Keran, Elstrott Justin, Weber Martin, Saillet Sandrine, Khan Abdullah S, Simms Jeffrey, Liu Benjamin, Kim Thomas A, Yu Gui-Qiu, Chen Yelin, Wang Tzu-Ming, Jiang Zhiyu, Liederer Bianca M, Deshmukh Gauri, Solanoy Hilda, Chan Connie, Sellers Benjamin D, Volgraf Matthew, Schwarz Jacob B, Hackos David H, Weimer Robby M, Sheng Morgan, Gill T Michael, Scearce-Levie Kimberly, Palop Jorge J

chemalot and chemalot_knime: Command line programs as workflow tools for drug discovery

chemalot 和 chemalot_knime:用于药物发现的命令行程序工作流程工具

Lee, Man-Ling; Aliagas, Ignacio; Feng, Jianwen A; Gabriel, Thomas; O'Donnell, T J; Sellers, Benjamin D; Wiswedel, Bernd; Gobbi, Alberto

Antibodies as a model system for comparative model refinement

抗体作为比较模型改进的模型系统

Sellers, Benjamin D; Nilmeier, Jerome P; Jacobson, Matthew P

Improving the species cross-reactivity of an antibody using computational design

利用计算机设计提高抗体的物种交叉反应性

Farady, Christopher J; Sellers, Benjamin D; Jacobson, Matthew P; Craik, Charles S

Toward better refinement of comparative models: predicting loops in inexact environments

为了更好地改进比较模型:预测不精确环境下的循环

Sellers, Benjamin D; Zhu, Kai; Zhao, Suwen; Friesner, Richard A; Jacobson, Matthew P