日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mito-tempol and dexrazoxane exhibit cardioprotective and chemotherapeutic effects through specific protein oxidation and autophagy in a syngeneic breast tumor preclinical model.

在同源乳腺肿瘤临床前模型中,Mito-tempol 和 dexrazoxane 通过特定的蛋白质氧化和自噬表现出心脏保护和化疗作用

Dickey Jennifer S, Gonzalez Yanira, Aryal Baikuntha, Mog Steven, Nakamura Asako J, Redon Christophe E, Baxa Ulrich, Rosen Elliot, Cheng Gang, Zielonka Jacek, Parekh Palak, Mason Karen P, Joseph Joy, Kalyanaraman Balaraman, Bonner William, Herman Eugene, Shacter Emily, Rao V Ashutosh

The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone

抗氧化转录因子 Nrf2 负向调节抗癌氧化还原剂米托醌诱导的自噬和生长停滞

V Ashutosh Rao, Sarah R Klein, Spencer J Bonar, Jacek Zielonka, Naoko Mizuno, Jennifer S Dickey, Paul W Keller, Joy Joseph, Balaraman Kalyanaraman, Emily Shacter

Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin

氧化剂诱导的细胞凋亡是由肌动蛋白调节蛋白cofilin的氧化介导的。

Klamt, Fábio; Zdanov, Stéphanie; Levine, Rodney L; Pariser, Ashley; Zhang, Yaqin; Zhang, Baolin; Yu, Li-Rong; Veenstra, Timothy D; Shacter, Emily

Auto-oxidation and oligomerization of protein S on the apoptotic cell surface is required for Mer tyrosine kinase-mediated phagocytosis of apoptotic cells

凋亡细胞表面蛋白 S 的自氧化和寡聚化是 Mer 酪氨酸激酶介导的凋亡细胞吞噬作用所必需的

Hiroshi Uehara, Emily Shacter

Update in Health Disparities

健康差异最新进展

Kerr, Eve A; Heisler, Michele; Krein, Sarah L; Kabeto, Mohammed; Langa, Kenneth M; Weir, David; Piette, John D; Washington, Donna L; Shacter, Hannah E; Saha, Somnath; Cooper, Lisa A; Long, Judith A

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues

药理抗坏血酸浓度选择性杀死癌细胞:作为前药将过氧化氢输送到组织

Qi Chen, Michael Graham Espey, Murali C Krishna, James B Mitchell, Christopher P Corpe, Garry R Buettner, Emily Shacter, Mark Levine

Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75

Rac1通过刺激Bad蛋白Ser-75位点的磷酸化来抑制人淋巴瘤细胞的凋亡。

Zhang, Baolin; Zhang, Yaqin; Shacter, Emily

DNA repair in the c-myc proto-oncogene locus: possible involvement in susceptibility or resistance to plasmacytoma induction in BALB/c mice

c-myc原癌基因位点的DNA修复:可能与BALB/c小鼠浆细胞瘤的易感性或抵抗性有关

Beecham, E J; Mushinski, J F; Shacter, E; Potter, M; Bohr, V A