日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ULK1 promotes metastatic progression in experimental models of epithelial ovarian cancer.

ULK1 在上皮性卵巢癌的实验模型中促进转移进展。

Webb Jack D, Buensuceso Adrian, Tomas Emily J, Borrelli Matthew J, Viola Lauren, Hovey Owen, Ramos Valdes Yudith, Singha Bipradeb, Li Shawn S-C, Shepherd Trevor G

HDAC Inhibition Induces Transient Phenotypic Inertia in Dormant OCCC Spheroids by Derepression of Cell Cycle Genes

HDAC抑制通过解除细胞周期基因的抑制,诱导休眠OCCC球体产生短暂的表型惰性

Cheng, Sylvia; Kolendowski, Bart; Ramos-Valdes, Yudith; Shepherd, Trevor G; DiMattia, Gabriel E

Evaluating carboplatin and PARP inhibitor combination efficacy using high-grade serous carcinoma spheroids and organoids

利用高级别浆液性癌球体和类器官评估卡铂和PARP抑制剂联合治疗的疗效

Tomas, Emily J; Davis, Jennifer; Ramos Valdes, Yudith; Shepherd, Trevor G

Evaluating the Therapeutic Potential of MRT68921 and Afatinib in Three-Dimensional Models of Epithelial Ovarian Cancer

在三维上皮性卵巢癌模型中评估MRT68921和阿法替尼的治疗潜力

Johnston, Tiffany P A; Webb, Jack D; Borrelli, Matthew J; Tomas, Emily J; Pucchio, Áine C; Valdés, Yudith Ramos; Shepherd, Trevor G

Chronic Viral Mimicry Induction following p53 Loss Promotes Immune Evasion.

p53 缺失后诱导慢性病毒模拟可促进免疫逃逸。

Ishak Charles A, Marhon Sajid A, Tchrakian Naïri, Hodgson Anjelica, Loo Yau Helen, Gonzaga Isabela M, Peralta Melanie, Lungu Ilinca M, Gomez Stephanie, Liang Sheng-Ben, Shen Shu Yi, Chen Raymond, Chen Jocelyn, Chatterjee Biji, Wanniarachchi Kevin N, Lee Junwoo, Zehrbach Nicholas, Hosseini Amir, Mehdipour Parinaz, Sun Siyu, Solovyov Alexander, Ettayebi Ilias, Francis Kyle E, He Aobo, Wu Taiyi, Feng Shengrui, da Silva Medina Tiago, Campos de Almeida Felipe, Bayani Jane, Li Jason, MacDonald Spencer, Wang Yadong, Garcia Sarah S, Arthofer Elisa, Diab Noor, Srivastava Aneil, Austin Paul Tran, Sabatini Peter J B, Greenbaum Benjamin D, O'Brien Catherine A, Shepherd Trevor G, Tsao Ming Sound, Chiappinelli Katherine B, Oza Amit M, Clarke Blaise A, Rottapel Robert, Lheureux Stephanie, De Carvalho Daniel D

Exploiting Cancer Dormancy Signaling Mechanisms in Epithelial Ovarian Cancer Through Spheroid and Organoid Analysis.

通过球状体和类器官分析,探索上皮性卵巢癌的癌症休眠信号机制

Tomas Emily J, Valdes Yudith Ramos, Davis Jennifer, Kolendowski Bart, Buensuceso Adrian, DiMattia Gabriel E, Shepherd Trevor G

Spatiotemporal analysis of ratiometric biosensors in live multicellular spheroids using SPoRTS.

利用SPoRTS对活体多细胞球体中的比率生物传感器进行时空分析

Borrelli Matthew J, Kolendowski Bart, DiMattia Gabriel E, Shepherd Trevor G

CAMKKβ supports growth and viability of epithelial ovarian cancer in vitro and in vivo.

CAMKKβ 在体外和体内均能促进上皮性卵巢癌的生长和存活

Borrelli Matthew J, Buensuceso Adrian, Ramos Valdes Yudith, Johnston Tiffany P A, Haagsma Jacob, Shepherd Trevor G

Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma

在同源原位卵巢高级别浆液性癌小鼠模型中,Trp53 的缺失会导致 T 细胞表型活性降低,并伴有促炎信号传导减弱。

Haagsma, Jacob; Valdes, Yudith Ramos; Ou, Xuejin; Rashu, Rasheduzzaman; Haeryfar, S M Mansour; Petrik, Jim; Shepherd, Trevor G

Insights into targeting LKB1 in tumorigenesis

肿瘤发生过程中靶向LKB1的见解

Trelford, Charles B; Shepherd, Trevor G