日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dominant-negative TP53 mutations potentiated by the HSF1-regulated proteostasis network

显性负性TP53突变受HSF1调控的蛋白质稳态网络增强

Halim, Stephanie; Sebastian, Rebecca M; Liivak, Kristi E; Patrick, Jessica E; Hui, Tiffani; Amici, David R; Giacomelli, Andrew O; Rios, Paulina; Butty, Vincent L; Hahn, William C; Sánchez-Rivera, Francisco J; Mendillo, Marc L; Lin, Yu-Shan; Shoulders, Matthew D

Hepatic zinc deficiency dampens the acute phase response in patients with alcohol-associated hepatitis

肝脏锌缺乏会减弱酒精性肝炎患者的急性期反应。

Read, Scott A; Ramezani-Moghadam, Mehdi; Gloss, Brian S; Nguyen, Romario; Woodham, Benjamin; Lam, Vincent; Yuen, Lawrence; Yoon, Jimin; Qiao, Liang; Tu, Thomas; George, Jacob; Shoulders, Matthew D; Ahlenstiel, Golo

Failed cellular surveillance enables pathogenic matrix deposition in a COL2A1-related osteoarthritis.

细胞监视功能障碍导致致病性基质沉积,从而引发 COL2A1 相关骨关节炎

Yammine Kathryn M, Mirda Abularach Sophia, Xiong Michael, Kim Seo-Yeon, Bikovtseva Agata A, Butty Vincent L, Schiavoni Richard P, Bateman John F, Lamandé Shireen R, Shoulders Matthew D

Endoplasmic Reticulum Oxidative Stress Promotes Glutathione-Dependent Oxidation of Collagen-1A1 and Promotes Lung Fibroblast Activation.

内质网氧化应激促进谷胱甘肽依赖的胶原蛋白-1A1氧化,并促进肺成纤维细胞活化

Druso Joseph E, MacPherson Maximilian B, Chia Shi B, Elko Evan, Aboushousha Reem, Seward David J, Abdelhamid Hend, Erickson Cuixia, Corteselli Elizabeth, Tarte Megan, Peng Zhihua, Bernier Daniel, Zito Ester, Shoulders Matthew D, Thannickal Victor J, Huang Steven, van der Vliet Albert, Anathy Vikas, Janssen-Heininger Yvonne M W

Protein Glycosylation Patterns Shaped By the IRE1-XBP1s Arm of the Unfolded Protein Response

未折叠蛋白反应的IRE1-XBP1s通路塑造蛋白质糖基化模式

Chen, Kenny; Shoulders, Matthew D

Expanded MutaT7 toolkit efficiently and simultaneously accesses all possible transition mutations in bacteria

扩展的 MutaT7 工具包能够高效且同时地检测细菌中所有可能的转换突变。

Mengiste, Amanuella A; Wilson, Robert H; Weissman, Rachel F; Papa Iii, Louis J; Hendel, Samuel J; Moore, Christopher L; Butty, Vincent L; Shoulders, Matthew D

Viral Evolution Shaped by Host Proteostasis Networks

宿主蛋白质稳态网络塑造病毒进化

Yoon, Jimin; Patrick, Jessica E; Ogbunugafor, C Brandon; Shoulders, Matthew D

In vivo hypermutation and continuous evolution

体内超突变和持续进化

Molina, Rosana S; Rix, Gordon; Mengiste, Amanuella A; Alvarez, Beatriz; Seo, Daeje; Chen, Haiqi; Hurtado, Juan; Zhang, Qiong; Donato García-García, Jorge; Heins, Zachary J; Almhjell, Patrick J; Arnold, Frances H; Khalil, Ahmad S; Hanson, Andrew D; Dueber, John E; Schaffer, David V; Chen, Fei; Kim, Seokhee; Ángel Fernández, Luis; Shoulders, Matthew D; Liu, Chang C

Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis

热休克因子1的缺失会促进肝星状细胞活化并驱动肝纤维化。

Choudhury, Asmita; Ratna, Anuradha; Lim, Arlene; Sebastian, Rebecca M; Moore, Christopher L; Filliol, Aveline A; Bledsoe, Jacob; Dai, Chengkai; Schwabe, Robert F; Shoulders, Matthew D; Mandrekar, Pranoti

Collagen misfolding mutations: the contribution of the unfolded protein response to the molecular pathology

胶原蛋白错误折叠突变:未折叠蛋白反应对分子病理学的贡献

Bateman, John F; Shoulders, Matthew D; Lamandé, Shireen R