日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Spatial transcriptomics for gene discovery identifies Slc13a5 as a modulator of bone mechanoadaptation

利用空间转录组学进行基因发现,鉴定出Slc13a5是骨骼力学适应的调节因子

Meslier, Quentin A; Beeve, Alec T; Gupta, Arushi; Palomo, Daniel; Saleem, Samia; Eck, Serena; Lawson, Lisa; Shuster, John; Brennan, Michelle; Dirckx, Naomi; Silva, Matthew J; Scheller, Erica L

Spatial histomorphometry reveals that local peripheral nerves modulate but are not required for skeletal adaptation to applied load in mice.

空间组织形态计量学表明,局部周围神经可以调节小鼠骨骼对施加负荷的适应,但并非其必需

Beeve Alec T, Hassan Mohamed G, Li Anna, Migotsky Nicole, Silva Matthew J, Scheller Erica L

Proliferation of Early and Mature Osteoblasts Is Required for Bone Fracture Healing in Mice

小鼠骨折愈合需要早期和成熟成骨细胞的增殖

Gould, Nicole R; Coello, Andre F; McKenzie, Jennifer A; Li, Tiandao; Hixon, Katherine R; Chen, Leyi; Barwick, Kristen; Lee, Tiffany; Obaji, Mariam; Zhang, Bo; Ornitz, David M; Silva, Matthew J

Multi-scale cortical bone traits vary in females and males from two mouse models of genetic diversity

来自两种遗传多样性小鼠模型的雌性和雄性小鼠的多尺度皮质骨特征存在差异

Migotsky, Nicole; Kumar, Surabhi; Shuster, John T; Coulombe, Jennifer C; Senwar, Bhavya; Gestos, Adrian A; Farber, Charles R; Ferguson, Virginia L; Silva, Matthew J

Multi-organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2)

缺乏潜伏性TGFβ结合蛋白2(LTBP2)的小鼠的多器官表型

Bodmer, Nicholas K; Knutsen, Russell H; Roth, Robyn A; Castile, Ryan M; Brodt, Michael D; Gierasch, Carrie M; Broekelmann, Thomas J; Gibson, Mark A; Haspel, Jeffrey A; Lake, Spencer P; Koenitzer, Jeffrey R; Brody, Steven L; Silva, Matthew J; Mecham, Robert P; Ornitz, David M

T cells heal bone fractures with help from the gut microbiome

T细胞在肠道微生物群的帮助下修复骨折。

Aurora, Rajeev; Silva, Matthew J

Multi-Scale Cortical Bone Traits Vary in Two Mouse Models of Genetic Diversity

两种遗传多样性小鼠模型中多尺度皮质骨性状存在差异

Migotsky, Nicole; Kumar, Surabhi; Shuster, John T; Coulombe, Jennifer C; Senwar, Bhavya; Gestos, Adrian A; Farber, Charles R; Ferguson, Virginia L; Silva, Matthew J

Loading-induced bone formation is mediated by Wnt1 induction in osteoblast-lineage cells

负重诱导的骨形成是由成骨细胞谱系细胞中 Wnt1 的诱导介导的。

Lawson, Lisa Y; Migotsky, Nicole; Chermside-Scabbo, Christopher J; Shuster, John T; Joeng, Kyu Sang; Civitelli, Roberto; Lee, Brendan; Silva, Matthew J

Postnatal Osterix but not DMP1 lineage cells significantly contribute to intramembranous ossification in three preclinical models of bone injury.

在三种骨损伤临床前模型中,出生后的 Osterix 细胞(而非 DMP1 谱系细胞)对膜内成骨有显著贡献

Buettmann Evan G, Yoneda Susumu, Hu Pei, McKenzie Jennifer A, Silva Matthew J

Cortical bone relationships are maintained regardless of sex and diet in a large population of LGXSM advanced intercross mice

在大量LGXSM高级杂交小鼠中,皮质骨关系不受性别和饮食的影响。

Migotsky, Nicole; Brodt, Michael D; Cheverud, James M; Silva, Matthew J