日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A broad survey of choanoflagellates revises the evolutionary history of the Shaker family of voltage-gated K(+) channels in animals

对领鞭毛虫的广泛调查修正了动物体内Shaker家族电压门控K(+)通道的进化史。

Jegla, Timothy; Simonson, Benjamin T; Spafford, J David

A governance of ion selectivity based on the occupancy of the "beacon" in one- and four-domain calcium and sodium channels

基于单域和四域钙钠通道中“信标”占据情况的离子选择性调控

Spafford, J David

Asynchronous Delivery of a 400 Level, Partially Peer-Graded, Oral Presentation and Discussion Course in Systems Neuroscience for 60 Students during the COVID-19 Pandemic

在新冠疫情期间,面向60名学生以异步方式教授400级系统神经科学课程,该课程采用部分同伴互评、口头报告和讨论的形式。

Moffat, Jack; Copas, Charlotte; Wood, Kate; Spafford, J David

Eukaryotic Voltage-Gated Sodium Channels: On Their Origins, Asymmetries, Losses, Diversification and Adaptations

真核生物电压门控钠通道:其起源、不对称性、丢失、多样化和适应性

Fux, Julia E; Mehta, Amrit; Moffat, Jack; Spafford, J David

Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels

电压门控钠通道、钙通道和NALCN通道中的选择性过滤器和富含半胱氨酸的细胞外环

Stephens, Robert F; Guan, W; Zhorov, Boris S; Spafford, J David

T-type channels become highly permeable to sodium ions using an alternative extracellular turret region (S5-P) outside the selectivity filter.

T 型通道利用选择性过滤器之外的替代细胞外塔状区 (S5-P) 对钠离子具有高度通透性

Senatore Adriano, Guan Wendy, Boone Adrienne N, Spafford J David

Gene splicing of an invertebrate beta subunit (LCavβ) in the N-terminal and HOOK domains and its regulation of LCav1 and LCav2 calcium channels.

无脊椎动物β亚基(LCavβ)在N端和HOOK结构域的基因剪接及其对LCav1和LCav2钙通道的调控

Dawson Taylor F, Boone Adrienne N, Senatore Adriano, Piticaru Joshua, Thiyagalingam Shano, Jackson Daniel, Davison Angus, Spafford J David

The calmodulin-binding, short linear motif, NSCaTE is conserved in L-type channel ancestors of vertebrate Cav1.2 and Cav1.3 channels

钙调蛋白结合的短线性基序NSCaTE在脊椎动物Cav1.2和Cav1.3通道的L型通道祖先中保守存在

Taiakina, Valentina; Boone, Adrienne N; Fux, Julia; Senatore, Adriano; Weber-Adrian, Danielle; Guillemette, J Guy; Spafford, J David

NALCN ion channels have alternative selectivity filters resembling calcium channels or sodium channels

NALCN离子通道具有类似于钙通道或钠通道的替代选择性过滤器。

Senatore, Adriano; Monteil, Arnaud; van Minnen, Jan; Smit, August B; Spafford, J David

Gene transcription and splicing of T-type channels are evolutionarily-conserved strategies for regulating channel expression and gating

T型通道的基因转录和剪接是进化上保守的调控通道表达和门控的策略。

Senatore, Adriano; Spafford, J David