日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Generation of hiPSC-Derived Brain Microvascular Endothelial Cells Using Directed Differentiation and Transcriptional Reprogramming

利用定向分化和转录重编程生成hiPSC衍生的脑微血管内皮细胞

Cui, Aomeng; Patel, Ronak; Bosco, Patrick; Akcan, Uğur; Richters, Emily; Barrilero Delgado, Paula; Agalliu, Dritan; Sproul, Andrew A

High throughput identification of genetic regulators of microglial inflammatory processes in Alzheimer's disease

利用高通量方法鉴定阿尔茨海默病中小胶质细胞炎症过程的遗传调控因子

Cardona, Christopher L; Wei, Lai; Kim, Joonwon; Angeles, Ellen; Singh, Gunjandeep; Chen, Shiye; Patel, Ronak; Ifediora, Nkechime; Canoll, Peter; Teich, Andrew F; Hargus, Gunnar; Chavez, Alejandro; Sproul, Andrew A

A proteogenomic tool uncovers protein markers for human microglial states

蛋白质基因组学工具揭示了人类小胶质细胞状态的蛋白质标志物

Haage, Verena; Bautista, Alex R; Tuddenham, John; Marshe, Victoria; Chiu, Rebecca; Liu, YunDuo; Lama, Tsering; Kelly, Shane S; Parghi, Neelang A; Park, Junho; Buonfiglioli, Alice; Furnari, Julia L; Haq, Imdadul; Pearse, Richard; Patel, Ronak; Terzioglu, Gizem; Touil, Hanane; Zeng, Lu; Noble, James; Sarkis, Rani A; Shneider, Neil A; de Witte, Lotje D; Schneider, Julie; Teich, Andrew; Young-Pearse, Tracy L; Riley, Claire; Bennett, David A; Canoll, Peter; Bruce, Jeffrey N; Howden, Andrew J M; Lloyd, Amy F; de Strooper, Bart; Sher, Falak; Sproul, Andrew A; Olah, Marta; Taga, Mariko; Zhang, Ya; Caisheng, Lu; Fujita, Masashi; Petyuk, Vladislav A; De Jager, Philip L

Reduced SH3RF3 may protect against Alzheimer's disease by lowering microglial pro-inflammatory responses via modulation of JNK and NFkB signaling

SH3RF3 减少可能通过调节 JNK 和 NFkB 信号通路降低小胶质细胞的促炎反应,从而起到预防阿尔茨海默病的作用。

Patel, Ronak; Cheng, Rong; Cardona, Christopher L; Angeles, Ellen; Singh, Gunjandeep; Miller, Sabrina; Ashok, Archana; Teich, Andrew F; Piriz, Angel; Maldonado, Aleyda; Jimenez-Velazquez, Ivonne Z; Mayeux, Richard; Lee, Joseph H; Sproul, Andrew A

Generating iAstrocytes From Human Induced Pluripotent Stem Cells by Combining Low-Density Passaging of Neural Progenitor Cells and Transcription Factor NFIA Transdifferentiation.

通过低密度传代神经祖细胞和转录因子NFIA转分化,从人类诱导多能干细胞生成i星形胶质细胞

Bosco Patrick, Akcan Ugur, Williams Damian, Buchanan Heather M, Agalliu Dritan, Sproul Andrew A

Generation of iPSC lines from archived non-cryoprotected biobanked dura mater

利用存档的非冷冻保护生物样本库硬脑膜生成iPSC系

Sproul, Andrew A; Vensand, Lauren B; Dusenberry, Carmen R; Jacob, Samson; Vonsattel, Jean Paul G; Paull, Daniel J; Shelanski, Michael L; Crary, John F; Noggle, Scott A