日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Therapeutic Potential of TLR8 Agonist GS-9688 (Selgantolimod) in Chronic Hepatitis B: Remodeling of Antiviral and Regulatory Mediators

TLR8 激动剂 GS-9688(Selgantolimod)在慢性乙型肝炎中的治疗潜力:抗病毒和调节介质的重塑

Oliver E Amin, Emily J Colbeck, Stephane Daffis, Shahzada Khan, Dhivya Ramakrishnan, Divya Pattabiraman, Ruth Chu, Holly Micolochick Steuer, Sophie Lehar, Leanne Peiser, Adam Palazzo, Christian Frey, Jessica Davies, Hassan Javanbakht, William M C Rosenberg, Simon P Fletcher, Mala K Maini, Laura J Pa

A temporal role of type I interferon signaling in CD8+ T cell maturation during acute West Nile virus infection

急性西尼罗河病毒感染期间 I 型干扰素信号在 CD8+ T 细胞成熟中的时间作用

Amelia K Pinto, Stephane Daffis, James D Brien, Maria D Gainey, Wayne M Yokoyama, Kathleen C F Sheehan, Kenneth M Murphy, Robert D Schreiber, Michael S Diamond

The innate immune adaptor molecule MyD88 restricts West Nile virus replication and spread in neurons of the central nervous system

先天免疫衔接分子MyD88可限制西尼罗病毒在中枢神经系统神经元中的复制和传播。

Kristy J Szretter ,Stephane Daffis, Jigisha Patel, Mehul S Suthar, Robyn S Klein, Michael Gale Jr, Michael S Diamond

Induction of IFN-beta and the innate antiviral response in myeloid cells occurs through an IPS-1-dependent signal that does not require IRF-3 and IRF-7

髓系细胞中IFN-β的诱导和先天性抗病毒反应是通过IPS-1依赖性信号传导发生的,该信号传导不需要IRF-3和IRF-7。

Stephane Daffis ,Mehul S Suthar, Kristy J Szretter, Michael Gale Jr, Michael S Diamond

Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection

干扰素调节因子IRF-7诱导抗病毒α干扰素反应,并能抵御致命的西尼罗河病毒感染。

Stephane Daffis ,Melanie A Samuel, Mehul S Suthar, Brian C Keller, Michael Gale Jr, Michael S Diamond