Effect of variations in the amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the human small intestine on PBPK models for predicting intestinal first pass
人类小肠中 P-糖蛋白 (ABCB1)、BCRP (ABCG2) 和 CYP3A4 含量变化对预测肠道首过效应的 PBPK 模型的影响
期刊:Molecular Pharmaceutics
影响因子:3.2
doi:10.1021/mp100015x
Arnaud Bruyère, Xavier Declèves, Francois Bouzom, Kathryn Ball, Catie Marques, Xavier Treton, Marc Pocard, Patrice Valleur, Yoram Bouhnik, Yves Panis, Jean-Michel Scherrmann, Stephane Mouly
