日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multi-omic analysis in normal colon organoids highlights MSH4 as a novel marker of defective mismatch repair in Lynch syndrome and microsatellite instability

正常结肠类器官中的多组学分析表明 MSH4 是林奇综合征和微卫星不稳定性中错配修复缺陷的新标记

Matthew Devall, Mourad W Ali, Stephen Eaton, Daniel J Weisenberger, Matthew J Reilley, Steven M Powell, Li Li, Graham Casey

Assessment of Colorectal Cancer Risk Factors through the Application of Network-Based Approaches in a Racially Diverse Cohort of Colon Organoid Stem Cells

通过应用基于网络的方法对种族多样化的结肠类器官干细胞队列进行结直肠癌风险因素评估

Matthew Devall, Stephen Eaton, Cynthia Yoshida, Steven M Powell, Graham Casey, Li Li

DNA methylation analysis of normal colon organoids from familial adenomatous polyposis patients reveals novel insight into colon cancer development

家族性腺瘤性息肉病患者正常结肠类器官的 DNA 甲基化分析揭示了结肠癌发展的新见解

Matthew A Devall, Stephen Eaton, Mourad Wagdy Ali, Christopher H Dampier, Daniel Weisenberger, Steven M Powell, Li Li, Graham Casey

Transcriptomic Response to Calcium in Normal Colon Organoids is Impacted by Colon Location and Sex

正常结肠类器官对钙的转录组反应受结肠位置和性别的影响

Matthew A M Devall #, Christopher H Dampier #, Stephen Eaton, Mourad Wagdy Ali, Sarah J Plummer, Jennifer Bryant, W James Gauderman, Ulrike Peters, Steven M Powell, Graham Casey

Insights into Early Onset Colorectal Cancer through Analysis of Normal Colon Organoids of Familial Adenomatous Polyposis Patients

通过分析家族性腺瘤性息肉病患者的正常结肠类器官洞察早发性结直肠癌

Matthew A Devall, Stephen Eaton, Mourad W Ali, Steven M Powell, Li Li, Graham Casey

Ethanol exposure drives colon location specific cell composition changes in a normal colon crypt 3D organoid model

乙醇暴露导致正常结肠隐窝 3D 类器官模型中结肠位置特异性细胞组成发生变化

Matthew Devall, Sarah J Plummer, Jennifer Bryant, Lucas T Jennelle, Stephen Eaton, Christopher H Dampier, Jeroen R Huyghe, Ulrike Peters, Steven M Powell, Graham Casey

Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes

CCK2R 体细胞突变会改变受体活性,从而促进致癌表型

Melinda D Willard, Mary E Lajiness, Isabella H Wulur, Bo Feng, Michelle L Swearingen, Mark T Uhlik, Kenneth W Kinzler, Victor E Velculescu, Tobias Sjöblom, Sanford D Markowitz, Steven M Powell, Bert Vogelstein, Thomas D Barber

Expression of tight-junction protein claudin-7 is an early event in gastric tumorigenesis

紧密连接蛋白 claudin-7 的表达是胃肿瘤发生的早期事件

Adam H Johnson, Henry F Frierson, Alexander Zaika, Steven M Powell, James Roche, Sheila Crowe, Christopher A Moskaluk, Wa'el El-Rifai

Simultaneous detection of CpG methylation and single nucleotide polymorphism by denaturing high performance liquid chromatography

变性高效液相色谱法同时检测CpG甲基化和单核苷酸多态性

Dajun Deng, Guoren Deng, Michael F Smith, Jing Zhou, Huijun Xin, Steven M Powell, Youyong Lu

Accurate, noninvasive detection of Helicobacter pylori DNA from stool samples: potential usefulness for monitoring treatment

准确、无创地检测粪便样本中的幽门螺杆菌 DNA:对监测治疗有潜在用途

Anthony P Shuber, Jennifer J Ascaño, Kevin A Boynton, Anastasia Mitchell, Henry F Frierson Jr, Wa'el El-Rifai, Steven M Powell