日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Double bond configuration of palmitoleate is critical for atheroprotection

棕榈油酸酯的双键结构对于动脉粥样硬化预防至关重要

Ismail Cimen, Zehra Yildirim, Asli Ekin Dogan, Asli Dilber Yildirim, Ozlem Tufanli, Umut Inci Onat, UyenThao Nguyen, Steven M Watkins, Christian Weber, Ebru Erbay

Dual actions of a novel bifunctional compound to lower glucose in mice with diet-induced insulin resistance

新型双功能化合物的双重作用可降低饮食引起的胰岛素抵抗小鼠的血糖。

Katherine Chen, Alice Jih, Sarah T Kavaler, William S Lagakos, Dayoung Oh, Steven M Watkins, Jane J Kim

A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice

Gpr120 选择性激动剂可改善肥胖小鼠的胰岛素抵抗和慢性炎症

Da Young Oh, Evelyn Walenta, Taro E Akiyama, William S Lagakos, Denise Lackey, Ariane R Pessentheiner, Roman Sasik, Nasun Hah, Tyler J Chi, Jason M Cox, Mary Ann Powels, Jerry Di Salvo, Christopher Sinz, Steven M Watkins, Aaron M Armando, Heekyung Chung, Ronald M Evans, Oswald Quehenberger, Joanne M

Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity

脂肪细胞耗氧量增加会触发 HIF-1α,导致肥胖患者出现炎症和胰岛素抵抗

Yun Sok Lee, Jung-Whan Kim, Olivia Osborne, Da Young Oh, Roman Sasik, Simon Schenk, Ai Chen, Heekyung Chung, Anne Murphy, Steven M Watkins, Oswald Quehenberger, Randall S Johnson, Jerrold M Olefsky

Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy

小鼠心脏酰基辅酶a合成酶1缺乏会损害脂肪酸氧化并诱导心脏肥大

Jessica M Ellis, Shannon M Mentock, Michael A Depetrillo, Timothy R Koves, Shiraj Sen, Steven M Watkins, Deborah M Muoio, Gary W Cline, Heinrich Taegtmeyer, Gerald I Shulman, Monte S Willis, Rosalind A Coleman

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

GPR120 是一种 omega-3 脂肪酸受体,可介导强效的抗炎和胰岛素增敏作用

Da Young Oh, Saswata Talukdar, Eun Ju Bae, Takeshi Imamura, Hidetaka Morinaga, WuQiang Fan, Pingping Li, Wendell J Lu, Steven M Watkins, Jerrold M Olefsky

Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice

饮食诱导的肥胖小鼠中 CD11c 阳性脂肪组织巨噬细胞的功能异质性

Pingping Li, Min Lu, M T Audrey Nguyen, Eun Ju Bae, Justin Chapman, Daorong Feng, Meredith Hawkins, Jeffrey E Pessin, Dorothy D Sears, Anh-Khoi Nguyen, Arezou Amidi, Steven M Watkins, UyenThao Nguyen, Jerrold M Olefsky

Complex I-associated hydrogen peroxide production is decreased and electron transport chain enzyme activities are altered in n-3 enriched fat-1 mice

在富含 n-3 的 fat-1 小鼠中,复合物 I 相关的过氧化氢生成减少,电子传递链酶活性发生改变

Kevork Hagopian, Kristina L Weber, Darren T Hwee, Alison L Van Eenennaam, Guillermo López-Lluch, José M Villalba, Isabel Burón, Plácido Navas, J Bruce German, Steven M Watkins, Yana Chen, Alfreda Wei, Roger B McDonald, Jon J Ramsey

Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition

肝脏特异性长链酰基辅酶 A 合成酶-1 的缺失会降低三酰甘油的合成和 β-氧化,并改变磷脂脂肪酸的组成

Lei O Li, Jessica M Ellis, Heather A Paich, Shuli Wang, Nan Gong, George Altshuller, Randy J Thresher, Timothy R Koves, Steven M Watkins, Deborah M Muoio, Gary W Cline, Gerald I Shulman, Rosalind A Coleman