日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Chromosomal tethering and mitotic transcription promote ecDNA nuclear inheritance.

染色体连接和有丝分裂转录促进ecDNA核遗传

Nichols Ashley, Choi Yujin, Norman Roshan Xavier, Chen Yanyang, Striepen Josefine, Salataj Eralda, Toufektchan Eléonore, Koche Richard, Maciejowski John

Mechanism of DNA replication fork breakage and PARP1 hyperactivation during replication catastrophe

DNA复制叉断裂和PARP1过度激活在复制灾难中的机制

Ortega, Pedro; Bournique, Elodie; Li, Junyi; Sanchez, Ambrocio; Santiago, Gisselle; Harris, Brooke R; Striepen, Josefine; Maciejowski, John; Green, Abby M; Buisson, Rémi

Identification of α-Azacyclic Acetamide-Based Inhibitors of P. falciparum Na(+) Pump (PfATP4) with Fast-Killing Asexual Blood-Stage Antimalarial Activity by Phenotypic Screening

通过表型筛选鉴定具有快速杀灭无性血液期疟原虫活性的α-氮杂环乙酰胺类恶性疟原虫钠泵(PfATP4)抑制剂

Casas, Arturo Jr; Imlay, Leah S; Thathy, Vandana; Fairhurst, Kate J; Lehane, Adele M; Lawong, Aloysus K; Deni, Ioanna; Striepen, Josefine; Lee, Seungheon; Kumar, Ashwani; Xing, Chao; Niederstrasser, Hanspeter; Posner, Bruce A; Laleu, Benoît; Charman, Susan A; Fidock, David A; Ready, Joseph M; Phillips, Margaret A

Identification of α-azacyclic acetamide-based inhibitors of P. falciparum Na (+) pump ( Pf ATP4) with fast-killing asexual blood-stage antimalarial activity by phenotypic screening

通过表型筛选鉴定出具有快速杀灭无性血液期疟原虫活性的α-氮杂环乙酰胺类恶性疟原虫钠泵(Pf ATP4)抑制剂

Casas, Arturo; Imlay, Leah S; Thathy, Vandana; Fairhurst, Kate J; Lehane, Adele M; Lawong, Aloysus K; Deni, Ionna; Striepen, Josefine; Lee, Seungheon; Kumar, Ashwani; Xing, Chao; Niederstrasser, Hanspeter; Posner, Bruce A; Laleu, Benoît; Charman, Susan A; Fidock, David A; Ready, Joseph M; Phillips, Margaret A

Comparison of Proximal and Distal Osteotomy in Minimally Invasive Hallux Valgus Surgery: A Retrospective Cohort Study

微创拇外翻手术中近端截骨术与远端截骨术的比较:一项回顾性队列研究

Nichols, Ashley; Norman, Roshan; Chen, Yanyang; Choi, Yujin; Striepen, Josefine; Salataj, Eralda; Toufektchan, Eleonore; Koche, Richard; Maciejowski, John; Seo, Young-Wook; Park, Young-uk

A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo.

一种强效且选择性的恶性疟原虫酪氨酸 tRNA 合成酶反应劫持抑制剂在体内表现出单剂量口服疗效

Xie Stanley C, Tai Chia-Wei, Morton Craig J, Ma Liting, Huang Shih-Chung, Wittlin Sergio, Du Yawei, Hu Yongbo, Dogovski Con, Salimimarand Mina, Griffin Robert, England Dylan, de la Cruz Elisa, Deni Ioanna, Yeo Tomas, Burkhard Anna Y, Striepen Josefine, Schindler Kyra A, Crespo Benigno, Gamo Francisco J, Khandokar Yogesh, Hutton Craig A, Rabie Tayla, Birkholtz Lyn-Marié, Famodimu Mufuliat T, Delves Michael J, Bolsher Judith, Koolen Karin M J, van der Laak Rianne, Aguiar Anna C C, Pereira Dhelio B, Guido Rafael V C, Creek Darren J, Fidock David A, Dick Lawrence R, Brand Stephen L, Gould Alexandra E, Langston Steven, Griffin Michael D W, Tilley Leann

APOBEC Mutagenesis in Cancer Development and Susceptibility

APOBEC诱变在癌症发生发展和易感性中的作用

Dananberg, Alexandra; Striepen, Josefine; Rozowsky, Jacob S; Petljak, Mia

Author Correction: Propensity of selecting mutant parasites for the antimalarial drug cabamiquine

作者更正:抗疟药物卡巴米喹对突变寄生虫的选择倾向

Stadler, Eva; Maiga, Mohamed; Friedrich, Lukas; Thathy, Vandana; Demarta-Gatsi, Claudia; Dara, Antoine; Sogore, Fanta; Striepen, Josefine; Oeuvray, Claude; Djimdé, Abdoulaye A; Lee, Marcus C S; Dembélé, Laurent; Fidock, David A; Khoury, David S; Spangenberg, Thomas

Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362

高效、有效、口服的抗疟疾血浆蛋白酶X抑制剂的发现与表征及UCB7362的临床前安全性评估

Lowe, Martin A; Cardenas, Alvaro; Valentin, Jean-Pierre; Zhu, Zhaoning; Abendroth, Jan; Castro, Jose L; Class, Reiner; Delaunois, Annie; Fleurance, Renaud; Gerets, Helga; Gryshkova, Vitalina; King, Lloyd; Lorimer, Donald D; MacCoss, Malcolm; Rowley, Julian H; Rosseels, Marie-Luce; Royer, Leandro; Taylor, Richard D; Wong, Melanie; Zaccheo, Oliver; Chavan, Vishal P; Ghule, Gokul A; Tapkir, Bapusaheb K; Burrows, Jeremy N; Duffey, Maëlle; Rottmann, Matthias; Wittlin, Sergio; Angulo-Barturen, Iñigo; Jiménez-Díaz, María Belén; Striepen, Josefine; Fairhurst, Kate J; Yeo, Tomas; Fidock, David A; Cowman, Alan F; Favuzza, Paola; Crespo-Fernandez, Benigno; Gamo, Francisco Javier; Goldberg, Daniel E; Soldati-Favre, Dominique; Laleu, Benoît; de Haro, Teresa

Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in Plasmodium falciparum

新型抗疟四唑类和酰胺类药物可有效抑制恶性疟原虫的血红蛋白降解途径

Lawong, Aloysus; Gahalawat, Suraksha; Okombo, John; Striepen, Josefine; Yeo, Tomas; Mok, Sachel; Deni, Ioanna; Bridgford, Jessica L; Niederstrasser, Hanspeter; Zhou, Anwu; Posner, Bruce; Wittlin, Sergio; Gamo, Francisco Javier; Crespo, Benigno; Churchyard, Alisje; Baum, Jake; Mittal, Nimisha; Winzeler, Elizabeth; Laleu, Benoît; Palmer, Michael J; Charman, Susan A; Fidock, David A; Ready, Joseph M; Phillips, Margaret A