日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lipid-laden endothelial cells exhibit a transcriptomic signature linked to blood-brain barrier dysfunction, metabolic reprogramming, and increased inflammation in the aging brain

脂质沉积的内皮细胞表现出与血脑屏障功能障碍、代谢重编程以及衰老大脑中炎症增加相关的转录组特征

Otu-Boakye, Sarah; Natarajan, Duraipandy; Plakkot, Bhuvana; Raghavendiran, Ilakiya; Hoppa, Paulina; Kiss, Tamas; Subramanian, Madhan; Balasubramanian, Priya

Chronic β3 adrenergic agonist treatment improves neurovascular coupling responses, attenuates blood-brain barrier leakage and neuroinflammation, and enhances cognition in aged mice.

慢性β3肾上腺素能激动剂治疗可改善神经血管耦合反应,减轻血脑屏障渗漏和神经炎症,并增强老年小鼠的认知能力

Natarajan Duraipandy, Ekambaram Shoba, Tarantini Stefano, Nagaraja Raghavendra Y, Yabluchanskiy Andriy, Hedrick Andria F, Awasthi Vibhudutta, Subramanian Madhan, Csiszar Anna, Balasubramanian Priya

Lipid-laden endothelial cells exhibit a transcriptomic signature linked to blood-brain barrier dysfunction, metabolic reprogramming and increased inflammation in the aging brain

脂质沉积的内皮细胞表现出与血脑屏障功能障碍、代谢重编程和衰老脑组织炎症增加相关的转录组特征

Otu-Boakye, Sarah; Natarajan, Duraipandy; Plakkot, Bhuvana; Raghavendiran, Ilakiya; Kiss, Tamas; Subramanian, Madhan; Balasubramanian, Priya

Revisiting adipose thermogenesis for delaying aging and age-related diseases: Opportunities and challenges

重新审视脂肪组织产热在延缓衰老和预防老年相关疾病中的作用:机遇与挑战

Tarantini, Stefano; Subramanian, Madhan; Butcher, Joshua T; Yabluchanskiy, Andriy; Li, Xinna; Miller, Richard A; Balasubramanian, Priya

Implications of Hypothalamic Neural Stem Cells on Aging and Obesity-Associated Cardiovascular Diseases

下丘脑神经干细胞对衰老和肥胖相关心血管疾病的影响

Plakkot, Bhuvana; Di Agostino, Ashley; Subramanian, Madhan

Obesity as a premature aging phenotype - implications for sarcopenic obesity

肥胖作为一种过早衰老表型——对肌少症性肥胖的启示

Nunan, Emily; Wright, Carson L; Semola, Oluwayemisi A; Subramanian, Madhan; Balasubramanian, Priya; Lovern, Pamela C; Fancher, Ibra S; Butcher, Joshua T

Herpes Simplex Virus Type 1 Preferentially Enhances Neuro-Inflammation and Senescence in Brainstem of Female Mice

单纯疱疹病毒1型优先增强雌性小鼠脑干的神经炎症和衰老

Sivasubramanian, Mahesh Kumar; Monteiro, Raisa; Harrison, Kelly S; Plakkot, Bhuvana; Subramanian, Madhan; Jones, Clinton

Aging is associated with glial senescence in the brainstem - implications for age-related sympathetic overactivity

衰老与脑干神经胶质细胞衰老有关——这对年龄相关的交感神经过度活跃具有重要意义。

Balasubramanian, Priya; Branen, Lyndee; Sivasubramanian, Mahesh Kumar; Monteiro, Raisa; Subramanian, Madhan

Non-invasive vagus nerve stimulation attenuates proinflammatory cytokines and augments antioxidant levels in the brainstem and forebrain regions of Dahl salt sensitive rats

非侵入性迷走神经刺激可减弱达尔盐敏感大鼠脑干和前脑区域的促炎细胞因子并提高抗氧化剂水平

Subramanian, Madhan; Edwards, Laura; Melton, Avery; Branen, Lyndee; Herron, Angela; Sivasubramanian, Mahesh Kumar; Monteiro, Raisa; Stansbury, Samantha; Balasubramanian, Priya; Morris, Lynsie; Elkholey, Khaled; Niewiadomska, Monika; Stavrakis, Stavros

Obesity-induced sympathoexcitation is associated with Nrf2 dysfunction in the rostral ventrolateral medulla

肥胖引起的交感神经兴奋与延髓腹外侧前部 Nrf2 功能障碍有关

Balasubramanian, Priya; Asirvatham-Jeyaraj, Ninitha; Monteiro, Raisa; Sivasubramanian, Mahesh Kumar; Hall, Delton; Subramanian, Madhan