日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Loss of FoxO in skeletal muscle leads to disrupted muscle metabolism and exacerbates starvation-induced hepatic steatosis

骨骼肌中FoxO的缺失会导致肌肉代谢紊乱，并加剧饥饿引起的肝脂肪变性。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2600036123
Oyabu, Mamoru; Sakaue, Manato; Kubo, Atsushi; Yoshioka, Kiyoshi; Kawaguchi, Runa; Yamamoto, Haruki; Kinjo, Yuzuka; Kwon, Jungin; Nishi, Hiroki; Yamanaka, Daisuke; Sato, Tomoki; Mori, Daiki; Eguchi, Takahiro; Ito, Naoki; Fukada, So-Ichiro; Suganami, Takayoshi; Miura, Shinji; Ono, Yusuke; Hakuno, Fumihiko; Takahashi, Shin-Ichiro; Goto, Tsuyoshi; Kamei, Yasutomi
代谢
发表日期：2026
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Brain lipid profiles and oligodendrocyte gene expression show discordant responses to high-fat diet in Alzheimer's disease mice

阿尔茨海默病小鼠的脑脂质谱和少突胶质细胞基因表达对高脂饮食的反应不一致。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-38129-y
Kawade, Noe; Komine, Okiru; Sobue, Akira; Kakimi, Chihiro; Tanaka, Miyako; Suganami, Takayoshi; Shimada, Mayuko; Ogi, Tomoo; Ikeda, Kazutaka; Horiuchi, Mai; Watanabe, Seiji; Saito, Takashi; Yamanaka, Koji
胶质细胞
阿尔茨海默症
神经科学
细胞生物学
发表日期：2026
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Risk of Venous Thromboembolism with Pemafibrate in Dyslipidemia: A Nationwide, Retrospective, Cohort Study Using a Japanese Claims Database

血脂异常患者服用培马贝特发生静脉血栓栓塞的风险：一项基于日本医疗保险数据库的全国性回顾性队列研究

期刊:
影响因子:
doi:10.1007/s43441-025-00883-y
Ikeda, Kenichiro; Tada, Mika; Nakano, Shun; Tsushio, Takuma; Watanabe, Yoshinari; Minamikawa, Sara; Ishiguro, Chieko; Yokoyama, Kenji; Fujisawa, Kenji; Tanahashi, Masaya; Suganami, Hideki; Kasano, Atsushi
心血管
发表日期：2026
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Novel Cell-to-Cell Communications Between Macrophages and Fibroblasts Regulate Obesity-Induced Adipose Tissue Fibrosis

巨噬细胞与成纤维细胞之间新型的细胞间通讯调控肥胖诱导的脂肪组织纤维化

期刊:Diabetes
影响因子:7.5
doi:10.2337/db24-0762
Kohda, Hiro; Tanaka, Miyako; Shichino, Shigeyuki; Arakawa, Satoko; Komori, Tadasuke; Ito, Ayaka; Wada, Eri; Ochi, Kozue; Yuan, Xunmei; Takeda, Takehiko; Saiki, Atsuhito; Tatsuno, Ichiro; Ikeda, Kenji; Miyai, Yuki; Enomoto, Atsushi; Morikawa, Yoshihiro; Shimizu, Shigeomi; Ueha, Satoshi; Matsushima, Kouji; Ogawa, Yoshihiro; Suganami, Takayoshi
巨噬细胞
成纤维细胞
巨噬细胞
信号转导
代谢
肥胖
细胞生物学
免疫/内分泌
发表日期：2025
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Transient Dietary Intervention Induces Healthy Adipose Tissue Expansion and Metabolically Healthy Obesity in Mice

短暂的饮食干预可诱导小鼠健康脂肪组织扩张和代谢健康的肥胖

期刊:FASEB Journal
影响因子:4.2
doi:10.1096/fj.202501121R
Wada, Eri; Hosono, Hirotaka; Tanaka, Miyako; Miyakawa, Fumi; Ochi, Kozue; Kohda, Hiro; Tanno, Shogo; Shimano, Reon; Ito, Ayaka; Kitaura, Yasuyuki; Ichihara, Kazuya; Matsumoto, Akinobu; Ogi, Tomoo; Satoh-Asahara, Noriko; Murohara, Toyoaki; Suganami, Takayoshi
肥胖
代谢
发表日期：2025
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Altered glycolipid metabolism during acute kidney injury exacerbates renal inflammation

急性肾损伤期间糖脂代谢改变会加剧肾脏炎症。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-28897-4
Osada, Akinori; Tanaka, Miyako; Sugiura, Yuki; Yuan, Xunmei; Yamashita, Shinji; Ochi, Kozue; Kohda, Hiro; Ito, Ayaka; Go, Shiori; Okajima, Tetsuya; Kadomatsu, Kenji; Yanagita, Motoko; Furuhashi, Kazuhiro; Maruyama, Shoichi; Suganami, Takayoshi
肾炎
炎症
炎症/感染
代谢
脂代谢
肾损伤
毒理研究
发表日期：2025
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Potent activity of prostaglandin J(2) on prostanoid DP receptors.

前列腺素 J(2) 对前列腺素 DP 受体具有强效活性

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.108523
Senoo Kanaho, Fukushima Keijo, Yamamoto Hitomi, Hamaguchi Ayaka, Suganami Akiko, Takano Harumi, Yamashita Mayu, Regan John W, Tamura Yutaka, Fujino Hiromichi
信号转导
发表日期：2025
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Efficacy and Safety of Pemafibrate, a Novel Selective PPARα Modulator in Chinese Patients with Dyslipidemia: A Double-Masked, Randomized, Placebo- and Active-Controlled Comparison Trial

新型选择性PPARα调节剂培马贝特治疗中国血脂异常患者的疗效和安全性：一项双盲、随机、安慰剂和活性药物对照试验

期刊:Journal of Atherosclerosis and Thrombosis
影响因子:2.8
doi:10.5551/jat.64112
Dai, Wenli; Lv, Qiang; Li, Qingling; Fu, Lu; Zhang, Yawei; Zhang, Yumin; Liu, Lijun; Tanigawa, Ryohei; Kunitomi, Keisuke; Kamei, Ryo; Suganami, Hideki; Ma, Changsheng
心血管
发表日期：2025
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Pharmacokinetics and Safety of Pemafibrate in Patients with both Dyslipidemia and Severe Renal Impairment: A Phase 4 Study

培马贝特在合并血脂异常和严重肾功能损害患者中的药代动力学和安全性：一项4期研究

期刊:Journal of Atherosclerosis and Thrombosis
影响因子:2.8
doi:10.5551/jat.64887
Ishibashi, Shun; Arai, Hidenori; Yokote, Koutaro; Araki, Eiichi; Watanabe, Mao; Nakanishi, Michiko; Makinose, Yuichi; Suganami, Hideki; Kurihara, Yuji; Yamashita, Shizuya
心血管
发表日期：2025
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Clinical Pharmacology of Pemafibrate Extended-release Formulation in Patients with Hypertriglyceridemia-A Phase 2, Multicenter, Active-controlled, Randomized, Single-blind, Crossover study

培马贝特缓释制剂治疗高甘油三酯血症患者的临床药理学研究——一项 II 期、多中心、活性对照、随机、单盲、交叉研究

期刊:Journal of Atherosclerosis and Thrombosis
影响因子:2.8
doi:10.5551/jat.65001
Yamashita, Shizuya; Araki, Eiichi; Arai, Hidenori; Yokote, Koutaro; Tanigawa, Ryohei; Saito, Ayumi; Suganami, Hideki; Minamikawa, Sara; Ishibashi, Shun
发表日期：2025
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