日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Potent Inhibitor of Caspase‑8 Based on the IL-18 Tetrapeptide Sequence Reveals Shared Specificities between Inflammatory and Apoptotic Initiator Caspases.

基于 IL-18 四肽序列的强效 Caspase-8 抑制剂揭示了炎症和凋亡起始 Caspase 之间的共同特异性

Bourne Christopher M, Raniszewski Nicole R, Mahale Ashutosh B, Kulkarni Madhura, Exconde Patrick M, Liu Sherry, Yost Winslow, Wrong Tristan J, Patio Robert C, Kardhashi Matilda, Shosanya Teni, Kambayashi Mirai, Discher Bohdana M, Brodsky Igor E, Burslem George M, Taabazuing Cornelius Y

Human non-canonical inflammasomes activate CASP3 to limit intracellular Salmonella replication in macrophages.

人类非经典炎症小体激活 CASP3 以限制巨噬细胞内沙门氏菌的复制。

Kulkarni Madhura, Bourne Christopher M, Mahale Ashutosh B, Exconde Patrick M, Murphy Cecelia, Cervantes Sofia, Kardhashi Matilda, Kambayashi Mirai, Yoo William, Wrong Tristan J, Patio Robert C, Discher Bohdana M, Taabazuing Cornelius Y

Chemical Tools Based on the Tetrapeptide Sequence of IL-18 Reveals Shared Specificities between Inflammatory and Apoptotic Initiator Caspases.

基于IL-18四肽序列的化学工具揭示了炎症和凋亡起始半胱天冬酶之间的共同特异性

Bourne Christopher M, Raniszewski Nicole R, Kulkarni Madhura, Exconde Patrick M, Liu Sherry, Yost Winslow, Wrong Tristan J, Patio Robert C, Mahale Ashutosh, Kardhashi Matilda, Shosanya Teni, Kambayashi Mirai, Discher Bohdana M, Brodsky Igor E, Burslem George M, Taabazuing Cornelius Y

Distinct sequential death complexes regulate pyroptosis and IL-1β release in response to Yersinia blockade of immune signaling

不同的顺序死亡复合物调节细胞焦亡和 IL-1β 释放,以响应耶尔森氏菌阻断免疫信号

Ronit Schwartz Wertman, Winslow Yost, Beatrice I Herrmann, Christopher M Bourne, Daniel Sorobetea, Christina K Go, Benedikt S Saller, Olaf Groß, Phillip Scott, Anthony Rongvaux, Cornelius Y Taabazuing, Igor E Brodsky

Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS

小鼠 caspase-11 的催化活性和自加工介导响应细胞浆 LPS 的非典型炎症小体组装

Daniel C Akuma #, Kimberly A Wodzanowski #, Ronit Schwartz Wertman #, Patrick M Exconde, Víctor R Vázquez Marrero, Chukwuma E Odunze, Daniel Grubaugh, Sunny Shin, Cornelius Taabazuing, Igor E Brodsky

Harnessing Pyroptosis for Cancer Immunotherapy

利用细胞焦亡进行癌症免疫治疗

Bourne, Christopher M; Taabazuing, Cornelius Y

Juneteenth in STEMM and the barriers to equitable science

六月节在 STEMM 领域以及实现科学公平的障碍

Mays, Alfred; Byars-Winston, Angela; Hinton, Antentor Jr; Marshall, Andrea G; Kirabo, Annet; August, Avery; Marlin, Bianca J; Riggs, Blake; Tolbert, Blanton; Wanjalla, Celestine; Womack, Chad; Evans, Chantell S; Barnes, Christopher; Starbird, Chrystal; Williams, Clintoria; Reynolds, Corey; Taabazuing, Cornelius; Cameron, Craig E; Murray, Debra D; Applewhite, Derek; Morton, Derrick J; Lee, Dexter; Williams, Dionna W; Lynch, Donald; Brady, Donita; Lynch, Erin; Rutaganira, Florentine U N; Silva, Gustavo M; Shuler, Haysetta; Saboor, Ishmail Abdus; Davis, Jamaine; Dzirasa, Kafui; Hammonds-Odie, Latanya; Reyes, Loretta; Sweetwyne, Mariya T; McReynolds, Melanie R; Johnson, Michael D L; Smith, Nathan A; Pittman, Nikea; Ajijola, Olujimi A; Smith, Quinton; Robinson, Renã A S; Lewis, Samantha C; Murray, Sandra A; Black, Sherilynn; Neal, Sonya E; Andrisse, Stanley; Townsend, Steven; Damo, Steven M; Griffith, Theanne N; Lambert, W Marcus; Clemons, William M Jr

The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases

IL-18 和 IL-1β 的四肽序列调节炎症胱天蛋白酶对其的募集和激活

Patrick M Exconde, Claudia Hernandez-Chavez, Christopher M Bourne, Rachel M Richards, Mark B Bray, Jan L Lopez, Tamanna Srivastava, Marisa S Egan, Jenna Zhang, William Yoo, Sunny Shin, Bohdana M Discher, Cornelius Y Taabazuing

Developing an in-depth understanding of patient and caregiver engagement across care transitions from hospital: protocol for a qualitative study exploring experiences in Canada

深入了解患者和照护者在从医院到医院的整个护理过渡过程中的参与情况:一项探索加拿大经验的定性研究方案

Elliott, Jacobi; van Wyk, Paula; Butler, Roy; Giosa, Justine L; Sims Gould, Joanie; Tong, Catherine E; Taabazuing, Mary Margaret; Johnson, Helen; Coyne, Paige; Mitchell, Fallon; Whate, Alexandra; Callon, Anne; Carson, Judith; Stolee, Paul

The tetrapeptide sequence of IL-1β regulates its recruitment and activation by inflammatory caspases

IL-1β 的四肽序列调节其通过炎症 caspase 的募集和激活

Patrick M Exconde, Claudia Hernandez-Chavez, Mark B Bray, Jan L Lopez, Tamanna Srivastava, Marisa S Egan, Jenna Zhang, Sunny Shin, Bohdana M Discher, Cornelius Y Taabazuing