日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Activation of N-Formyldipeptide-Masked Prodrugs by Human Peptide Deformylase

人肽去甲酰酶对N-甲酰二肽掩蔽前药的激活作用

Geißen, Raphael; Yildirim, Okan; Köhn, Maja; Scheinberg, David A; Tan, Derek S

Chalkophore mediated respiratory oxidase flexibility controls M. tuberculosis virulence.

叶绿素介导的呼吸氧化酶灵活性控制结核分枝杆菌的毒力

Buglino John A, Ozakman Yaprak, Hatch Chad E, Benjamin Anna, Tan Derek S, Glickman Michael S

Design and Semisynthesis of Biselectrophile-Functionalized Ubiquitin Probes To Investigate Transthioesterification Reactions

双亲电体功能化泛素探针的设计与半合成及其在转硫酯化反应研究中的应用

Delos Reyes, Avelyn Mae V; Lux, Michaelyn C; Hann, Zachary S; Ji, Cheng; Kochańczyk, Tomasz; DiBello, Mikaela; Lima, Christopher D; Tan, Derek S

Design and synthesis of a library of C2-substituted sulfamidoadenosines to probe bacterial permeability

设计和合成C2取代的磺酰胺腺苷库以探测细菌通透性

Zhao, Shibin; Maceren, Julian; Chung, Mia; Stone, Samantha; Geißen, Raphael; Boby, Melissa L; Sherborne, Bradley S; Tan, Derek S

Design and synthesis of a library of C8-substituted sulfamidoadenosines to probe bacterial permeability

设计和合成C8取代的磺酰胺腺苷库以探测细菌通透性

Yildirim, Okan; Barman, Dipti; Chung, Mia; Stone, Samantha; Geißen, Raphael; Boby, Melissa L; Sherborne, Bradley S; Tan, Derek S

Direct conversion of amino acids to oxetanol bioisosteres via photoredox catalysis

通过光氧化还原催化将氨基酸直接转化为氧杂环丁醇生物等排体

Delos Reyes, Avelyn Mae V; Nieves Escobar, Christopher S; Muñoz, Alberto; Huffman, Maya I; Tan, Derek S

Development of a p-Hydroxybenzyl-Alcohol-Linked Glutamate Prodrug for Activation by Pseudomonas Carboxypeptidase G2

开发一种对羟基苄醇连接的谷氨酸前药,用于铜绿假单胞菌羧肽酶G2的激活

Lee, J Peter; Corless, Broderick C; Gardner, Thomas J; Scheinberg, David A; Tan, Derek S

Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase

恶性疟原虫天冬酰胺tRNA合成酶的反应劫持抑制

Xie, Stanley C; Wang, Yinuo; Morton, Craig J; Metcalfe, Riley D; Dogovski, Con; Pasaje, Charisse Flerida A; Dunn, Elyse; Luth, Madeline R; Kumpornsin, Krittikorn; Istvan, Eva S; Park, Joon Sung; Fairhurst, Kate J; Ketprasit, Nutpakal; Yeo, Tomas; Yildirim, Okan; Bhebhe, Mathamsanqa N; Klug, Dana M; Rutledge, Peter J; Godoy, Luiz C; Dey, Sumanta; De Souza, Mariana Laureano; Siqueira-Neto, Jair L; Du, Yawei; Puhalovich, Tanya; Amini, Mona; Shami, Gerry; Loesbanluechai, Duangkamon; Nie, Shuai; Williamson, Nicholas; Jana, Gouranga P; Maity, Bikash C; Thomson, Patrick; Foley, Thomas; Tan, Derek S; Niles, Jacquin C; Han, Byung Woo; Goldberg, Daniel E; Burrows, Jeremy; Fidock, David A; Lee, Marcus C S; Winzeler, Elizabeth A; Griffin, Michael D W; Todd, Matthew H; Tilley, Leann

Cheminformatic analysis of natural product-based drugs and chemical probes

基于天然产物的药物和化学探针的化学信息学分析

Stone, Samantha; Newman, David J; Colletti, Steven L; Tan, Derek S

Defining new chemical space for drug penetration into Gram-negative bacteria

为药物渗透革兰氏阴性菌定义新的化学空间

Zhao, Shibin; Adamiak, Justyna W; Bonifay, Vincent; Mehla, Jitender; Zgurskaya, Helen I; Tan, Derek S