日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sigma-1-targeting multimodal compound HBK-15 reverses memory deficits and restores hippocampal plasticity under NMDA hypofunction

靶向Sigma-1的多模式化合物HBK-15可逆转NMDA功能低下引起的记忆缺陷并恢复海马可塑性。

Sałaciak, Kinga; Lustyk, Klaudia; Jagielska, Angelika; Szafarz, Małgorzata; Inteiro-Oliveira, Sara; Diógenes, Maria José; Xapelli, Sara; Schnur, Paulina; Morton, Lucy; Moran, Erin; Ferreira, Jacques; Sakata, Shuzo; Crouzier, Lucie; Meunier, Johann; Delprat, Benjamin; Maurice, Tangui; Pytka, Karolina

Perceived disabling physical pain and suicidal ideation in aging people living with HIV cured of hepatitis C: A multi-center survey in France (ANRS CO13 HEPAVIH)

法国一项多中心调查(ANRS CO13 HEPAVIH)显示,已治愈丙型肝炎的 HIV 感染老年患者感知到的致残性身体疼痛和自杀意念。

Barré, Tangui; Ramier, Clémence; Protopopescu, Camelia; Sogni, Philippe; Ory, Karine; Saidi, Tounes; Abgrall, Sophie; Brégigeon-Ronot, Sylvie; Carrieri, Patrizia; Marcellin, Fabienne

Positive modulation of sigma-1 receptor: a new weapon to mitigate disease progression in amyotrophic lateral sclerosis.

σ-1 受体的正向调节:缓解肌萎缩侧索硬化症疾病进展的新武器。

Le Friec Julien, Mourier Hugo, Couly Simon, Cubedo Nicolas, Dubois Kevin, Meunier Johann, Delprat Benjamin, De Zordo-Banliat Arnaud, Ayad Tahar, Virieux David, Su Tsung-Ping, Lasbleiz Christelle, Maurice Tangui, Liévens Jean-Charles

Neuroprotection by chronic administration of Fluoroethylnormemantine (FENM) in mouse models of Alzheimer's disease

长期服用氟乙基去甲美金刚胺 (FENM) 对阿尔茨海默病小鼠模型具有神经保护作用

Allison Carles, Aline Freyssin, Sarra Guehairia, Thomas Reguero, Michel Vignes, Hélène Hirbec, Gilles Rubinstenn, Tangui Maurice

Prevalence and factors associated with tobacco and cannabis co-use in France: Results from a national representative survey

法国烟草和大麻共同使用的流行情况及相关因素:一项全国代表性调查的结果

Barré, Tangui; Di Beo, Vincent; Protopopescu, Camelia; Lahaie, Emmanuel; Andler, Raphaël; Nguyen-Thanh, Viêt; Pasquereau, Anne; Carrieri, Patrizia; Beck, François

Amylovis-201 is a new dual-target ligand, acting as an anti-amyloidogenic compound and a potent agonist of the σ (1) chaperone protein

Amylovis-201 是一种新型双靶点配体,既具有抗淀粉样蛋白生成作用,又是 σ(1) 分子伴侣蛋白的强效激动剂。

García-Pupo, Laura; Crouzier, Lucie; Bencomo-Martínez, Alberto; Meunier, Johann; Morilleau, Axelle; Delprat, Benjamin; Carrazana, Marquiza Sablón; Menéndez Soto Del Valle, Roberto; Maurice, Tangui; Rodríguez-Tanty, Chryslaine

The Wolfram-like variant WFS1E864K destabilizes MAM and compromises autophagy and mitophagy in human and mice

Wolfram 样变体 WFS1E864K 会破坏 MAM 的稳定性,并损害人和小鼠的自噬和线粒体自噬。

Simone Patergnani ,Méghane S Bataillard ,Alberto Danese ,Stacy Alves ,Chantal Cazevieille ,René Valéro ,Lisbeth Tranebjærg ,Tangui Maurice ,Paolo Pinton ,Benjamin Delprat ,Elodie M Richard

Targeting N-Methyl-d-Aspartate Receptors in Neurodegenerative Diseases

靶向N-甲基-D-天冬氨酸受体治疗神经退行性疾病

Carles, Allison; Freyssin, Aline; Perin-Dureau, Florent; Rubinstenn, Gilles; Maurice, Tangui

The selective butyrylcholinesterase inhibitor UW-MD-95 shows symptomatic and neuroprotective effects in a pharmacological mouse model of Alzheimer's disease

选择性丁酰胆碱酯酶抑制剂 UW-MD-95 在阿尔茨海默病的药理小鼠模型中表现出对症和神经保护作用

Allison Carles, Matthias Hoffmann, Matthias Scheiner, Lucie Crouzier, Christelle Bertrand-Gaday, Arnaud Chatonnet, Michael Decker, Tangui Maurice

Long-Term Treatment with Fluoroethylnormemantine (FENM) Alleviated Memory Deficits, Amyloid Pathology, and Microglial Reaction in APP/PS1 Mice.

长期使用氟乙基去甲美金刚 (FENM) 治疗可减轻 APP/PS1 小鼠的记忆缺陷、淀粉样蛋白病理和小胶质细胞反应

Freyssin Aline, Carles Allison, Moha Barbara, Rubinstenn Gilles, Maurice Tangui