Thermal proteome profiling and proteome analysis using high-definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next-generation galeterone analog VNPP433-3β in castration-resistant prostate cancer.
利用高分辨率质谱进行热蛋白质组分析和蛋白质组分析，证明下一代加列酮类似物 VNPP433-3β 可以调节去势抵抗性前列腺癌中的胆固醇生物合成
期刊:Molecular Oncology
影响因子:4.5
doi:10.1002/1878-0261.70009
Thankan Retheesh S, Thomas Elizabeth, Weldemariam Mehari M, Purushottamachar Puranik, Huang Weiliang, Kane Maureen A, Zhang Yuji, Ambulos Nicholas, Wang Bi-Dar, Weber David, Njar Vincent C O
