日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

GSK-3 Inhibition Is Cytotoxic in Glioma Stem Cells through Centrosome Destabilization and Enhances the Effect of Radiotherapy in Orthotopic Models

GSK-3 抑制剂通过中心体不稳定对胶质瘤干细胞产生细胞毒性,并增强原位模型中放射治疗的效果

Anke Brüning-Richardson, Gary C Shaw, Daniel Tams, Tim Brend, Hitesh Sanganee, Simon T Barry, Gregory Hamm, Richard J A Goodwin, John G Swales, Henry King, Lynette Steele, Ruth Morton, Anastasia Widyadari, Thomas A Ward, Filomena Esteves, Marjorie Boissinot, Georgia Mavria, Alastair Droop, Sean E La

EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma

EGFRvIII 上调 DNA 错配修复,导致 MGMT 启动子甲基化胶质母细胞瘤对替莫唑胺的敏感性增加

Nina Struve, Zev A Binder, Lucy F Stead, Tim Brend, Stephen J Bagley, Claire Faulkner, Leonie Ott, Justus Müller-Goebel, Anna-Sophie Weik, Konstantin Hoffer, Leonie Krug, Thorsten Rieckmann, Lara Bußmann, Marvin Henze, Jennifer J D Morrissette, Kathreena M Kurian, Ulrich Schüller, Cordula Petersen, 

Drug-Repositioning Screens Identify Triamterene as a Selective Drug for the Treatment of DNA Mismatch Repair Deficient Cells

药物重新定位筛选确定氨苯蝶啶是治疗 DNA 错配修复缺陷细胞的选择性药物

Delphine Guillotin, Philip Austin #, Rumena Begum #, Marta O Freitas, Ashirwad Merve, Tim Brend, Susan Short, Silvia Marino, Sarah A Martin

RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells

RAD51 是一种选择性 DNA 修复靶标,可增强胶质瘤干细胞的放射敏感性

Harry O King, Tim Brend, Helen L Payne, Alexander Wright, Thomas A Ward, Karan Patel, Teklu Egnuni, Lucy F Stead, Anjana Patel, Heiko Wurdak, Susan C Short

The Her7 node modulates the network topology of the zebrafish segmentation clock via sequestration of the Hes6 hub

Her7 节点通过隔离 Hes6 枢纽来调节斑马鱼分割时钟的网络拓扑结构

Anna Trofka, Jamie Schwendinger-Schreck, Tim Brend, William Pontius, Thierry Emonet, Scott A Holley