日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A quantitative cell-based reporter links TDP-43 aggregation and dysfunction to define pathogenic mechanisms

一种基于细胞的定量报告系统将TDP-43聚集和功能障碍联系起来,从而阐明其致病机制。

Mamede, Lohany Dias; Hu, Miwei; Vaquer-Alicea, Jaime; Titus, Amanda R; Passos, Patricia M; Lantelme, Erica; French, Rachel L; Kirschner, Paige A; Diamond, Marc I; Miller, Timothy M; Ayala, Yuna M

Structural details of helix-mediated multimerization of the conserved region of TDP-43 C-terminal domain

TDP-43 C端结构域保守区螺旋介导多聚化的结构细节

Rizuan, Azamat; Shenoy, Jayakrishna; Mohanty, Priyesh; Dos Passos, Patricia M; Mercado Ortiz, José F; Bai, Leanna; Viswanathan, Renjith; Zaborowksy, Julia; Wang, Szu-Huan; Johnson, Victoria; Mamede, Lohany D; Titus, Amanda R; Ayala, Yuna M; Ghirlando, Rodolfo; Mittal, Jeetain; Fawzi, Nicolas L

The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway.

郝方丹综合征蛋白 USP7 通过一种新型的不依赖于 p53 的泛素信号通路调节大脑中的神经元连接

Chen Hao, Ferguson Cole J, Mitchell Dylan C, Risch Isabel, Titus Amanda, Paulo Joao A, Hwang Andrew, Beck Loren K, Lin Tsen-Hsuan, Gu Wei, Song Sheng-Kwei, Yuede Carla M, Yano Hiroko, Griffith Obi L, Griffith Malachi, Gygi Steven P, Bonni Azad, Kim Albert H

Manual assessment of cylinder rearing behavior is more sensitive than automated gait evaluations in young, male mice post-stroke of the forepaw somatosensory cortex.

对于前爪体感皮层中风后的年轻雄性小鼠,人工评估圆柱体站立行为比自动步态评估更为敏感

Li Cynthia X, Kapoor Esha, Chen Wei, Ward Lance M, Lee David D, Titus Amanda, Reardon Kate M, Lee Jin-Moo, Yuede Carla M, Landsness Eric C

Characterization of early markers of disease in the mouse model of mucopolysaccharidosis IIIB

粘多糖贮积症 IIIB 型小鼠模型早期疾病标志物的特征分析

McCullough, Katherine B; Titus, Amanda; Reardon, Kate; Conyers, Sara; Dougherty, Joseph D; Ge, Xia; Garbow, Joel R; Dickson, Patricia; Yuede, Carla M; Maloney, Susan E