日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A recurrent ACAA2 variant causes a dominant syndrome of lipodystrophy, lipomatosis, infantile steatohepatitis, and hypoglycemia

ACAA2基因的一种复发性变异会导致一种显性遗传综合征,其特征为脂肪营养不良、脂肪瘤病、婴儿脂肪性肝炎和低血糖症。

Simha, Vinaya; LoPiccolo, Mary Kate; Platt, Anna; Brown, Rebecca J; Johnson, Xandria; Carere, Deanna Alexis; Donnelly, Colleen; Snyder, Matthew T; Xing, Chao; Mathews, Thomas P; Gopal, Purva; Ward, Stephen C; Tomchick, Diana R; Agarwal, Anil K; DeBerardinis, Ralph J; Garg, Abhimanyu

Leptin as a key driver for organ fibrogenesis

瘦素是器官纤维化发生的关键驱动因素

Xue-Nan Sun,Shiuhwei Chen,Shangang Zhao,Jan-Bernd Funcke,Megan Virostek,Line Pedersen,Chao Li,Chanmin Joung,Qian Lin,Yan Li,Ayanna Cobb,May-Yun Wang,Kyounghee Min,Lisandro Maya-Ramos,Giovanna Degasperi,Junquan Liu,Ningyan Zhang,Zhiqiang An,Diana R Tomchick,R Max Wynn,Da Young Oh,Philipp E Scherer

Gain of Function NOTCH3 Variants Cause Familial Partial Lipodystrophy Due to Activation of Senescence Pathways

NOTCH3 功能获得性变异通过激活衰老通路导致家族性部分脂肪营养不良

Garg, Abhimanyu; Xing, Chao; Agarwal, Anil K; Westfall, Aundrea K; Tomchick, Diana R; Zhang, Xunzhi; Xing, Michelle; Brown, Rebecca J

Pseudomonas effector AvrB is a glycosyltransferase that rhamnosylates plant guardee protein RIN4

假单胞菌效应物 AvrB 是一种糖基转移酶,可对植物保护蛋白 RIN4 进行鼠李糖基化

Wei Peng, Nalleli Garcia, Kelly A Servage, Jennifer J Kohler, Joseph M Ready, Diana R Tomchick, Jessie Fernandez, Kim Orth

Exploiting bacterial effector proteins to uncover evolutionarily conserved antiviral host machinery

利用细菌效应蛋白揭示进化上保守的抗病毒宿主机制

Embry, Aaron; Baggett, Nina S; Heisler, David B; White, Addison; de Jong, Maarten F; Kocsis, Benjamin L; Tomchick, Diana R; Alto, Neal M; Gammon, Don B

Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation

对 5' 至 3' RNA 连接酶的生化和结构洞察揭示了其在 tRNA 连接中的潜在作用

Yingjie Hu #, Victor A Lopez #, Hengyi Xu, James P Pfister, Bing Song, Kelly A Servage, Masahiro Sakurai, Benjamin T Jones, Joshua T Mendell, Tao Wang, Jun Wu, Alan M Lambowitz, Diana R Tomchick, Krzysztof Pawłowski, Vincent S Tagliabracci

Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation

对 5' 至 3' RNA 连接酶的生物化学和结构研究揭示了其在 tRNA 连接中的潜在作用

Hu, Yingjie; Lopez, Victor A; Xu, Hengyi; Pfister, James P; Song, Bing; Servage, Kelly A; Sakurai, Masahiro; Jones, Benjamin T; Mendell, Joshua T; Wang, Tao; Wu, Jun; Lambowitz, Alan M; Tomchick, Diana R; Pawłowski, Krzysztof; Tagliabracci, Vincent S

Exploiting Bacterial Effector Proteins to Uncover Evolutionarily Conserved Antiviral Host Machinery

利用细菌效应蛋白揭示进化上保守的抗病毒宿主机制

Embry, Aaron; Baggett, Nina S; Heisler, David B; White, Addison; de Jong, Maarten F; Kocsis, Benjamin L; Tomchick, Diana R; Alto, Neal M; Gammon, Don B

Structural insights for selective disruption of Beclin 1 binding to Bcl-2

选择性破坏 Beclin 1 与 Bcl-2 结合的结构见解

Yun-Zu Pan, Qiren Liang, Diana R Tomchick, Jef K De Brabander, Josep Rizo

Molecular determinants for differential activation of the bile acid receptor from the pathogen Vibrio parahaemolyticus

病原体副溶血性弧菌胆汁酸受体差异激活的分子决定因素

Angela J Zou, Lisa Kinch, Suneeta Chimalapati, Nalleli Garcia, Diana R Tomchick, Kim Orth