Traphagen相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Lack of synergy between AR-targeted therapies and PARP inhibitors in homologous recombination-proficient prostate cancer

在同源重组功能正常的的前列腺癌中，AR靶向疗法与PARP抑制剂之间缺乏协同作用

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2515790122

Traphagen, Nicole A; Wheeler, Esmé; Li, Rong; Akhshi, Tara; Ravindranathan, Ramya; Alfieri, Christian; Lu, Feng; Ahmed, Buraq; Tewari, Alok K; Balk, Steven P; Nelson, Peter S; Corey, Eva; Long, Henry; D'Andrea, Alan D; Qiu, Xintao; Brown, Myles

发表日期：2026

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Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes

EZH2在晚期前列腺癌亚型中的谱系特异性经典和非经典活性

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-024-51156-5

Venkadakrishnan, Varadha Balaji; Presser, Adam G; Singh, Richa; Booker, Matthew A; Traphagen, Nicole A; Weng, Kenny; Voss, Nathaniel C E; Mahadevan, Navin R; Mizuno, Kei; Puca, Loredana; Idahor, Osasenaga; Ku, Sheng-Yu; Bakht, Martin K; Borah, Ashir A; Herbert, Zachary T; Tolstorukov, Michael Y; Barbie, David A; Rickman, David S; Brown, Myles; Beltran, Himisha

发表日期：2024

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Estrogen Therapy Induces Receptor-Dependent DNA Damage Enhanced by PARP Inhibition in ER+ Breast Cancer

雌激素疗法诱导 ER+乳腺癌中受体依赖性 DNA 损伤，PARP 抑制增强该损伤

期刊:Clinical Cancer Research

影响因子:10

doi:10.1158/1078-0432.CCR-23-0488

Nicole A Traphagen, Gary N Schwartz, Steven Tau, Alyssa M Roberts, Amanda Jiang, Sarah R Hosford, Jonathan D Marotti, Abigail E Goen, Bianca A Romo, Anneka L Johnson, Emily-Claire K Duffy, Eugene Demidenko, Paul Heverly, Yaron Mosesson, Shannon M Soucy, Fred Kolling, Todd W Miller

发表日期：2023

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High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer

高雌激素受体α活化可抵抗雌激素缺乏，并且是乳腺癌对雌激素治疗反应所必需的

期刊:Oncogene

影响因子:6.9

doi:10.1038/s41388-021-01782-w

Nicole A Traphagen, Sarah R Hosford, Amanda Jiang, Jonathan D Marotti, Brooke L Brauer, Eugene Demidenko, Todd W Miller

发表日期：2021

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A Transcriptionally Definable Subgroup of Triple-Negative Breast and Ovarian Cancer Samples Shows Sensitivity to HSP90 Inhibition

转录组学上可定义的三阴性乳腺癌和卵巢癌样本亚群对 HSP90 抑制剂敏感

期刊:Clinical Cancer Research

影响因子:10.2

doi:10.1158/1078-0432.CCR-18-2213

Shee, Kevin; Wells, Jason D; Ung, Matthew; Hampsch, Riley A; Traphagen, Nicole A; Yang, Wei; Liu, Stephanie C; Zeldenrust, Megan A; Wang, Liewei; Kalari, Krishna R; Yu, Jia; Boughey, Judy C; Demidenko, Eugene; Kettenbach, Arminja N; Cheng, Chao; Goetz, Matthew P; Miller, Todd W

发表日期：2020

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AMPK Activation by Metformin Promotes Survival of Dormant ER(+) Breast Cancer Cells

二甲双胍激活AMPK促进休眠ER(+)乳腺癌细胞的存活

期刊:Clinical Cancer Research

影响因子:10.2

doi:10.1158/1078-0432.CCR-20-0269

Hampsch, Riley A; Wells, Jason D; Traphagen, Nicole A; McCleery, Charlotte F; Fields, Jennifer L; Shee, Kevin; Dillon, Lloye M; Pooler, Darcy B; Lewis, Lionel D; Demidenko, Eugene; Huang, Yina H; Marotti, Jonathan D; Goen, Abigail E; Kinlaw, William B; Miller, Todd W

细胞生物学

发表日期：2020

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Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells

极低密度脂蛋白的内吞作用：乳腺癌细胞获取脂质的意外机制

期刊:Journal of Lipid Research

doi:10.1194/jlr.RA119000327

Leslie E Lupien, Katarzyna Bloch, Jonas Dehairs, Nicole A Traphagen, William W Feng, Wilson L Davis, Thea Dennis, Johannes V Swinnen, Wendy A Wells, Nicole C Smits, Nancy B Kuemmerle, Todd W Miller, William B Kinlaw

发表日期：2020

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Estrogen therapy induces an unfolded protein response to drive cell death in ER+ breast cancer

雌激素疗法诱导未折叠蛋白反应，导致 ER+ 乳腺癌细胞死亡

期刊:Molecular Oncology

doi:10.1002/1878-0261.12528

Sarah R Hosford, Kevin Shee, Jason D Wells, Nicole A Traphagen, Jennifer L Fields, Riley A Hampsch, Arminja N Kettenbach, Eugene Demidenko, Todd W Miller

细胞生物学

发表日期：2019

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Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER+ breast cancer

细胞因子敏感性筛选突出了 BMP4 通路信号传导作为 ER+ 乳腺癌的治疗机会

期刊:FASEB Journal

影响因子:4.4

doi:10.1096/fj.201801241R

Kevin Shee, Amanda Jiang, Frederick S Varn, Stephanie Liu, Nicole A Traphagen, Philip Owens, Cynthia X Ma, Jeremy Hoog, Chao Cheng, Todd R Golub, Ravid Straussman, Todd W Miller

发表日期：2019

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Tumor pharmacokinetics and pharmacodynamics of the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma

CDK4/6抑制剂ribociclib在复发性胶质母细胞瘤患者中的肿瘤药代动力学和药效学研究

期刊:Journal of Neuro-Oncology

影响因子:3.1

doi:10.1007/s11060-019-03258-0

Miller, Todd W; Traphagen, Nicole A; Li, Jing; Lewis, Lionel D; Lopes, Beatriz; Asthagiri, Ashok; Loomba, Johanna; De Jong, Jenny; Schiff, David; Patel, Sohil H; Purow, Benjamin W; Fadul, Camilo E

细胞生物学

发表日期：2019

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