日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

DYRK1A antagonists rescue degeneration and behavioural deficits of in vivo models based on amyloid-β, Tau and DYRK1A neurotoxicity

DYRK1A 拮抗剂可挽救基于淀粉样蛋白-β、Tau 和 DYRK1A 神经毒性的体内模型的退化和行为缺陷

Bangfu Zhu, Tom Parsons, Christopher Foley, Yeng Shaw, Travis Dunckley, Christopher Hulme, James J L Hodge

Dyrk1 inhibition improves Alzheimer's disease-like pathology

Dyrk1 抑制可改善阿尔茨海默病样病理

Caterina Branca, Darren M Shaw, Ramona Belfiore, Vijay Gokhale, Arthur Y Shaw, Christopher Foley, Breland Smith, Christopher Hulme, Travis Dunckley, Bessie Meechoovet, Antonella Caccamo, Salvatore Oddo

The Presence of Select Tau Species in Human Peripheral Tissues and Their Relation to Alzheimer's Disease

人类外周组织中某些 Tau 物种的存在及其与阿尔茨海默病的关系

Brittany N Dugger, Charisse M Whiteside, Chera L Maarouf, Douglas G Walker, Thomas G Beach, Lucia I Sue, Angelica Garcia, Travis Dunckley, Bessie Meechoovet, Eric M Reiman, Alex E Roher

SMG1 identified as a regulator of Parkinson's disease-associated alpha-synuclein through siRNA screening

通过 siRNA 筛选,SMG1 被鉴定为帕金森病相关 α-突触核蛋白的调节剂

Adrienne Henderson-Smith, Donald Chow, Bessie Meechoovet, Meraj Aziz, Sandra A Jacobson, Holly A Shill, Marwan N Sabbagh, John N Caviness, Charles H Adler, Erika D Driver-Dunckley, Thomas G Beach, Hongwei Yin, Travis Dunckley

Recent advances in the design, synthesis, and biological evaluation of selective DYRK1A inhibitors: a new avenue for a disease modifying treatment of Alzheimer's?

选择性 DYRK1A 抑制剂的设计、合成和生物学评估的最新进展:治疗阿尔茨海默病的新途径?

Breland Smith, Federico Medda, Vijay Gokhale, Travis Dunckley, Christopher Hulme

Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set

阿尔茨海默病对大脑不同区域神经元基因表达的改变:参考数据集

Winnie S Liang ,Travis Dunckley, Thomas G Beach, Andrew Grover, Diego Mastroeni, Keri Ramsey, Richard J Caselli, Walter A Kukull, Daniel McKeel, John C Morris, Christine M Hulette, Donald Schmechel, Eric M Reiman, Joseph Rogers, Dietrich A Stephan