日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Machine-guided dual-objective protein engineering for deimmunization and therapeutic functions.

利用机器引导的双目标蛋白质工程实现去免疫和治疗功能

Wolfsberg Eric, Paul Jean-Sebastien, Tycko Josh, Chen Binbin, Bassik Michael C, Bintu Lacramioara, Alizadeh Ash A, Gao Xiaojing J

Development of compact transcriptional effectors using high-throughput measurements in diverse contexts.

利用高通量测量在不同环境下开发紧凑型转录效应因子

Tycko Josh, Van Mike V, Aradhana, DelRosso Nicole, Ye Hanrong, Yao David, Valbuena Raeline, Vaughan-Jackson Alun, Xu Xiaoshu, Ludwig Connor, Spees Kaitlyn, Liu Katherine, Gu Mingxin, Khare Venya, Mukund Adi Xiyal, Suzuki Peter H, Arana Sophia, Zhang Catherine, Du Peter P, Ornstein Thea S, Hess Gaelen T, Kamber Roarke A, Qi Lei S, Khalil Ahmad S, Bintu Lacramioara, Bassik Michael C

A genome-wide genetic screen uncovers determinants of human pigmentation

全基因组遗传筛选揭示人类色素沉着的决定因素

Bajpai, Vivek K; Swigut, Tomek; Mohammed, Jaaved; Naqvi, Sahin; Arreola, Martin; Tycko, Josh; Kim, Tayne C; Pritchard, Jonathan K; Bassik, Michael C; Wysocka, Joanna

Modeling the efficacy of CRISPR gene drive for snail immunity on schistosomiasis control

利用CRISPR基因驱动技术增强蜗牛免疫力以控制血吸虫病的效果模型

Grewelle, Richard E; Perez-Saez, Javier; Tycko, Josh; Namigai, Erica K O; Rickards, Chloe G; De Leo, Giulio A

The sound of silence: Transgene silencing in mammalian cell engineering

寂静之声:哺乳动物细胞工程中的转基因沉默

Cabrera, Alan; Edelstein, Hailey I; Glykofrydis, Fokion; Love, Kasey S; Palacios, Sebastian; Tycko, Josh; Zhang, Meng; Lensch, Sarah; Shields, Cara E; Livingston, Mark; Weiss, Ron; Zhao, Huimin; Haynes, Karmella A; Morsut, Leonardo; Chen, Yvonne Y; Khalil, Ahmad S; Wong, Wilson W; Collins, James J; Rosser, Susan J; Polizzi, Karen; Elowitz, Michael B; Fussenegger, Martin; Hilton, Isaac B; Leonard, Joshua N; Bintu, Lacramioara; Galloway, Kate E; Deans, Tara L

Identification of Guide-Intrinsic Determinants of Cas9 Specificity

鉴定Cas9特异性的向导内在决定因素

Huston, Nicholas C; Tycko, Josh; Tillotson, Eric L; Wilson, Christopher J; Myer, Vic E; Jayaram, Hariharan; Steinberg, Barrett E

Gene drives for schistosomiasis transmission control

基因驱动控制血吸虫病传播

Maier, Theresa; Wheeler, Nicolas James; Namigai, Erica K O; Tycko, Josh; Grewelle, Richard Ernest; Woldeamanuel, Yimtubezinash; Klohe, Katharina; Perez-Saez, Javier; Sokolow, Susanne H; De Leo, Giulio A; Yoshino, Timothy P; Zamanian, Mostafa; Reinhard-Rupp, Jutta

Publisher Correction: Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells

出版商更正:成对文库筛选系统地探究了金黄色葡萄球菌Cas9在人细胞中的特异性

Tycko, Josh; Barrera, Luis A; Huston, Nicholas C; Friedland, Ari E; Wu, Xuebing; Gootenberg, Jonathan S; Abudayyeh, Omar O; Myer, Vic E; Wilson, Christopher J; Hsu, Patrick D

Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes

CRISPR介导的碱基编辑在真核生物基因组中的方法和应用

Hess, Gaelen T; Tycko, Josh; Yao, David; Bassik, Michael C

Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity

优化 CRISPR-Cas9 基因组编辑特异性的方法

Tycko, Josh; Myer, Vic E; Hsu, Patrick D