Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma
选择性 HDAC6 抑制剂 ACY-1215 与硼替佐米联合治疗多发性骨髓瘤的临床前活性、药效学和药代动力学特性
期刊:Blood
影响因子:21
doi:10.1182/blood-2011-10-387365
Loredana Santo, Teru Hideshima, Andrew L Kung, Jen-Chieh Tseng, David Tamang, Min Yang, Matthew Jarpe, John H van Duzer, Ralph Mazitschek, Walter C Ogier, Diana Cirstea, Scott Rodig, Homare Eda, Tyler Scullen, Miriam Canavese, James Bradner, Kenneth C Anderson, Simon S Jones, Noopur Raje
