日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cellular senescence in liver diseases: From molecular drivers to therapeutic targeting

肝脏疾病中的细胞衰老:从分子驱动因素到治疗靶点

Du, Kuo; Umbaugh, David S; Ren, Niansheng; Diehl, Anna Mae

Zinc-dependent RNA-binding protein controls hepatocyte senescence and recovery from alcohol-related liver failure

锌依赖性RNA结合蛋白调控肝细胞衰老和酒精性肝衰竭的恢复。

Dutta, Rajesh Kumar; Du, Kuo; Ren, Niansheng; Umbaugh, David S; Oh, Seh-Hoon; Wang, Liuyang; Kalsotra, Auinash; Blackshear, Perry J; Diehl, Anna Mae

Targeting senescent hepatocytes for treatment of metabolic dysfunction-associated steatotic liver disease and multi-organ dysfunction.

靶向衰老肝细胞治疗代谢功能障碍相关的脂肪肝疾病和多器官功能障碍

Du Kuo, Umbaugh David S, Wang Liuyang, Jun Ji Hye, Dutta Rajesh K, Oh Seh Hoon, Ren Niansheng, Zhang Qiaojuan, Ko Dennis C, Ferreira Ana, Hill Jon, Gao Guannan, Pullen Steven S, Jain Vaibhav, Gregory Simon, Abdelmalek Manal F, Diehl Anna Mae

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression.

cGAS抑制ALDH2以抑制脂滴功能并调节MASLD进展。

Wang Ying, Deng Yu, Chen Jianfeng, Hahn Quentin, Umbaugh David S, Zhang Zhigang, Zhang Yanqiong, Rowe Sarah E, Li Lupeng, Herring Laura E, Conlon Brian P, Miao Edward A, Damania Blossom, Diehl Anna Mae, Liu Pengda

Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma.

利用 DARPins 选择性靶向 TBXT 可识别脊索瘤的调控网络和治疗弱点

Umbaugh Charles S, Groth Marie, Erkut Cihan, Lee Kwang-Seok, Marinho Joana, Linder Simon, Iser Florian, Kapp Jonas N, Schroeter Petra, Dolaner Simay, Kayserili Asli, Helm Dominic, Schneider Martin, Hartmann Julia, Walch Philipp, Barth Thomas F E, Mellert Kevin, Dreier Birgit, Schaefer Jonas V, Plückthun Andreas, Fröhling Stefan, Scholl Claudia

Establishment of patient-derived 3D in vitro models of sarcomas: literature review and guidelines on behalf of the FORTRESS working group

建立源自患者的肉瘤三维体外模型:FORTRESS工作组的文献综述和指南

De Cock, Lore; Palubeckaitė, Ieva; Bersani, Francesca; Faehling, Tobias; Pasquali, Sandro; Umbaugh, Sam; Meister, Michael Torsten; Danks, Molly R; Manasterski, Piotr; Miallot, Richard; Krumbholz, Manuela; Roohani, Siyer; Heymann, Dominique; Cidre-Aranaz, Florencia; Wozniak, Agnieszka; Schöffski, Patrick; Bovée, Judith V M G; Merlini, Alessandra; Venneker, Sanne

Mixed lineage kinase domain-like protein deficiency exacerbates early injury in a mouse model of acetaminophen hepatotoxicity.

混合谱系激酶结构域样蛋白缺乏会加剧对乙酰氨基酚肝毒性小鼠模型中的早期损伤

Sanchez-Guerrero Giselle, Umbaugh David S, Smith Sawyer H, Akakpo Jephte Y, Jaeschke Hartmut, Ramachandran Anup

Proteomic profiling of adipose-derived mesenchymal stromal cell response to novel compounds targeting the Laminin Receptor - PEDF interaction

脂肪来源间充质干细胞对靶向层粘连蛋白受体-PEDF相互作用的新型化合物的反应的蛋白质组学分析

Figueiredo, Marxa L; Figueiredo Neto, Manoel; Umbaugh, C Samuel; Sobreira, Tiago J P; Elsbury, Claire E; Mulia, Grace E; Harris, Gabriel S; Lescun, Timothy B; Sintim, Herman O

Stigma in differences of sex development: a scoping review

性别发育差异中的污名:一项范围界定综述

Crerand, Canice E; Suorsa-Johnson, Kristina I; Ernst, Michelle M; Fei, Y Frances; Hansen-Moore, Jennifer; Jaffal, Nadia; James, LaTeesa N; Jewell, Tess; Johnson, Jodie; Lanphier, Elizabeth; Pennesi, Christine M; Umbaugh, Hailey; McClinchie, Madeline; Saylor, Kate M; Britt, Alexandra; Sandberg, David E

The chemokine CXCL14 is a novel early prognostic biomarker for poor outcome in acetaminophen-induced acute liver failure

趋化因子CXCL14是一种新型的早期预后生物标志物,可用于预测对乙酰氨基酚诱发的急性肝衰竭的不良预后。

Umbaugh, David S; Nguyen, Nga T; Curry, Steven C; Rule, Jody A; Lee, William M; Ramachandran, Anup; Jaeschke, Hartmut