Underwood Alexander相关文献与解析，生知库

Fahnøe, Ulrik; Feng, Shan; Underwood, Alexander P; Jacobsen, Kivin; Ameri, Amir; Blicher, Thomas H; Sølund, Christina S; Rosenberg, Brad R; Brix, Liselotte; Weis, Nina; Bukh, Jens

SARS-CoV-2

T细胞

信号转导

Cure of chronic hepatitis C virus infection after DAA treatment only partially restores the functional capacity of exhausted T cell subsets: a systematic review

DAA治疗后慢性丙型肝炎病毒感染的治愈仅能部分恢复耗竭T细胞亚群的功能：一项系统性综述

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1546915

Apol, Ása Didriksen; Sølund, Christina; Vinten, Caroline; Underwood, Alexander P; Bukh, Jens; Weis, Nina

Selective Mono- and Diamination of 2,6-Dibromopyridine for the Synthesis of Diaminated Proligands

2,6-二溴吡啶的选择性单胺化和双胺化反应用于合成双胺化前体配体

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.5c04396

Underwood, Alexander S; Botrous, Mark A; Lobb, Nate T; Neal, Emmett M; Richter, Charlotte A; Sleiman, Mathieu A; Frye, Adrian B; Roberts, Matthew; Padgett, Clifford W; Guillet, Gary L

发表日期：2025

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Higher Rates of Viral Evolution in Chronic Hepatitis B Patients Linked to Predicted T Cell Epitopes

慢性乙型肝炎患者病毒进化速度加快与预测的T细胞表位相关

期刊:Viruses-Basel

影响因子:3.5

doi:10.3390/v17050684

Dalegaard, Magnus Illum; Winckelmann, Anni; Fahnøe, Ulrik; Underwood, Alexander P; Pedersen, Anders Gorm; Bollerup, Signe; Bukh, Jens; Weis, Nina

Spike substitutions E484D, P812R and Q954H mediate ACE2-independent entry of SARS-CoV-2 across different cell lines.

刺突蛋白的 E484D、P812R 和 Q954H 突变介导 SARS-CoV-2 病毒不依赖 ACE2 进入不同细胞系

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0326419

Vizgirda Greta, Underwood Alexander P, FahnÃ¸e Ulrik, Weis Nina, Ramirez Santseharay, Bukh Jens

Neutralisation resistance of SARS-CoV-2 spike-variants is primarily mediated by synergistic receptor binding domain substitutions.

SARS-CoV-2 刺突蛋白变种的抗中和作用主要由受体结合域的协同替换介导

期刊:Emerging Microbes & Infections

影响因子:7.5

doi:10.1080/22221751.2024.2412643

Pham Long V, Underwood Alexander P, Binderup Alekxander, FahnÃ¸e Ulrik, Fernandez-Antunez Carlota, Lopez-Mendez Blanca, Ryberg Line Abildgaard, Galli Andrea, SÃ¸lund Christina, Weis Nina, Ramirez Santseharay, Bukh Jens

First-in-human use of a modular capsid virus-like vaccine platform: an open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2

首次在人体中使用模块化衣壳病毒样疫苗平台：SARS-CoV-2 疫苗 ABNCoV2 的开放标签、非随机、1 期临床试验

期刊:Lancet Microbe

影响因子:20.4

doi:10.1016/S2666-5247(22)00337-8

Smit, Merel J; Sander, Adam F; Ariaans, Maud B P A; Fougeroux, Cyrielle; Heinzel, Constanze; Fendel, Rolf; Esen, Meral; Kremsner, Peter G; Ter Heine, Rob; Wertheim, Heiman F; Idorn, Manja; Paludan, Søren Riis; Underwood, Alexander P; Binderup, Alekxander; Ramirez, Santseharay; Bukh, Jens; Soegaard, Max; Erdogan, Sayit M; Gustavsson, Tobias; Clemmensen, Stine; Theander, Thor G; Salanti, Ali; Hamborg, Mette; de Jongh, Willem A; McCall, Matthew B B; Nielsen, Morten A; Mordmüller, Benjamin G

Durability and breadth of neutralisation following multiple antigen exposures to SARS-CoV-2 infection and/or COVID-19 vaccination

多次接触SARS-CoV-2抗原感染和/或接种COVID-19疫苗后，中和作用的持久性和广度。

期刊:EBioMedicine

影响因子:10.8

doi:10.1016/j.ebiom.2023.104475

Underwood, Alexander P; Sølund, Christina; Fernandez-Antunez, Carlota; Villadsen, Signe Lysemose; Mikkelsen, Lotte S; Fahnøe, Ulrik; Bollerup, Signe; Winckelmann, Anni Assing; Schneider, Uffe Vest; Binderup, Alekxander; Vizgirda, Greta; Sørensen, Anna-Louise; Vinten, Caroline Nørløv; Dalegaard, Magnus Illum; Ramirez, Santseharay; Weis, Nina; Bukh, Jens

A Distinct Dexamethasone-Dependent Gene Expression Profile in the Lungs of COVID-19 Patients

新冠肺炎患者肺部存在独特的地塞米松依赖性基因表达谱

期刊:Journal of Infectious Diseases

影响因子:4.5

doi:10.1093/infdis/jiac218

Fahnøe, Ulrik; Ronit, Andreas; Berg, Ronan M G; Jørgensen, Sofie E; Mogensen, Trine H; Underwood, Alexander P; Scheel, Troels K H; Bukh, Jens; Plovsing, Ronni R

Analysis of Neutralization Titers against SARS-CoV-2 in Health-Care Workers Vaccinated with Prime-Boost mRNA-mRNA or Vector-mRNA COVID-19 Vaccines.

对接种了加强免疫 mRNA-mRNA 或载体-mRNA COVID-19 疫苗的医护人员体内针对 SARS-CoV-2 的中和抗体滴度进行分析

期刊:Vaccines

影响因子:3.4

doi:10.3390/vaccines10010075

SÃ¸lund Christina, Underwood Alexander P, Fernandez-Antunez Carlota, Bollerup Signe, Mikkelsen Lotte S, Villadsen Signe Lysemose, FahnÃ¸e Ulrik, Winckelmann Anni Assing, Feng Shan, NÃ¸rlÃ¸v Vinten Caroline A, Dalegaard Magnus Illum, Vizgirda Greta, SÃ¸rensen Anna-Louise, Ramirez Santseharay, Bukh Jens, Weis Nina

T cell receptor usage and epitope specificity amongst CD8(+) and CD4(+) SARS-CoV-2-specific T cells

CD8(+)和CD4(+) SARS-CoV-2特异性T细胞的T细胞受体使用情况和表位特异性

Cure of chronic hepatitis C virus infection after DAA treatment only partially restores the functional capacity of exhausted T cell subsets: a systematic review

DAA治疗后慢性丙型肝炎病毒感染的治愈仅能部分恢复耗竭T细胞亚群的功能：一项系统性综述

Selective Mono- and Diamination of 2,6-Dibromopyridine for the Synthesis of Diaminated Proligands

2,6-二溴吡啶的选择性单胺化和双胺化反应用于合成双胺化前体配体

Higher Rates of Viral Evolution in Chronic Hepatitis B Patients Linked to Predicted T Cell Epitopes

慢性乙型肝炎患者病毒进化速度加快与预测的T细胞表位相关

Spike substitutions E484D, P812R and Q954H mediate ACE2-independent entry of SARS-CoV-2 across different cell lines.

刺突蛋白的 E484D、P812R 和 Q954H 突变介导 SARS-CoV-2 病毒不依赖 ACE2 进入不同细胞系

Neutralisation resistance of SARS-CoV-2 spike-variants is primarily mediated by synergistic receptor binding domain substitutions.

SARS-CoV-2 刺突蛋白变种的抗中和作用主要由受体结合域的协同替换介导

First-in-human use of a modular capsid virus-like vaccine platform: an open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2

首次在人体中使用模块化衣壳病毒样疫苗平台：SARS-CoV-2 疫苗 ABNCoV2 的开放标签、非随机、1 期临床试验

Durability and breadth of neutralisation following multiple antigen exposures to SARS-CoV-2 infection and/or COVID-19 vaccination

多次接触SARS-CoV-2抗原感染和/或接种COVID-19疫苗后，中和作用的持久性和广度。

A Distinct Dexamethasone-Dependent Gene Expression Profile in the Lungs of COVID-19 Patients

新冠肺炎患者肺部存在独特的地塞米松依赖性基因表达谱

Analysis of Neutralization Titers against SARS-CoV-2 in Health-Care Workers Vaccinated with Prime-Boost mRNA-mRNA or Vector-mRNA COVID-19 Vaccines.

对接种了加强免疫 mRNA-mRNA 或载体-mRNA COVID-19 疫苗的医护人员体内针对 SARS-CoV-2 的中和抗体滴度进行分析