日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Enhancing the therapeutic index of [(211)At]YF2 with iodo pseudo carrier: A simple strategy for reducing accumulation in kidneys, salivary and lacrimal glands

利用碘化物假载体提高[(211)At]YF2的治疗指数:一种减少其在肾脏、唾液腺和泪腺中蓄积的简便策略

Huynh, Truc T; Feng, Yutian; Banks, Rebecca L; Vaidyanathan, Ganesan; Zalutsky, Michael R

A third generation PSMA-targeted agent [(211)At]YF2: Synthesis and in vivo evaluation

第三代PSMA靶向药物[(211)At]YF2:合成及体内评价

Feng, Yutian; Meshaw, Rebecca L; Finch, Sean W; Zheng, Yongxiang; Minn, Il; Vaidyanathan, Ganesan; Pomper, Martin G; Zalutsky, Michael R

Low-level whole-brain radiation enhances theranostic potential of single-domain antibody fragments for human epidermal growth factor receptor type 2 (HER2)-positive brain metastases

低剂量全脑放射治疗可增强单域抗体片段对人表皮生长因子受体2型(HER2)阳性脑转移瘤的诊疗潜力

Procissi, Daniele; Jannetti, Stephen A; Zannikou, Markella; Zhou, Zhengyuan; McDougald, Darryl; Kanojia, Deepak; Zhang, Hui; Burdett, Kirsten; Vaidyanathan, Ganesan; Zalutsky, Michael R; Balyasnikova, Irina V

An Improved (211)At-Labeled Agent for PSMA-Targeted α-Therapy

一种改进的(211)At标记的PSMA靶向α疗法药物

Mease, Ronnie C; Kang, Choong Mo; Kumar, Vivek; Banerjee, Sangeeta Ray; Minn, Il; Brummet, Mary; Gabrielson, Kathleen L; Feng, Yutian; Park, Andrew; Kiess, Ana P; Sgouros, George; Vaidyanathan, Ganesan; Zalutsky, Michael R; Pomper, Martin G

Gold Nanostars: A Novel Platform for Developing (211)At-Labeled Agents for Targeted Alpha-Particle Therapy

金纳米星:一种用于开发靶向α粒子治疗的(211)At标记剂的新型平台

Liu, Yang; Zhou, Zhengyuan; Feng, Yutian; Zhao, Xiao-Guang; Vaidyanathan, Ganesan; Zalutsky, Michael R; Vo-Dinh, Tuan

Synthesis and preliminary evaluation of (211)At-labeled inhibitors of prostate-specific membrane antigen for targeted alpha particle therapy of prostate cancer

合成并初步评价(211)At标记的前列腺特异性膜抗原抑制剂在前列腺癌靶向α粒子治疗中的应用

Vaidyanathan, Ganesan; Mease, Ronnie C; Minn, Il; Choi, Jaeyeon; Chen, Ying; Shallal, Hassan; Kang, Choong Mo; McDougald, Darryl; Kumar, Vivek; Pomper, Martin G; Zalutsky, Michael R

Site-Specific and Residualizing Linker for (18)F Labeling with Enhanced Renal Clearance: Application to an Anti-HER2 Single-Domain Antibody Fragment

用于 (18)F 标记并增强肾清除率的位点特异性和残留连接子:应用于抗 HER2 单域抗体片段

Zhou, Zhengyuan; Meshaw, Rebecca; Zalutsky, Michael R; Vaidyanathan, Ganesan

Labeling Monoclonal Antibody with α-emitting (211)At at High Activity Levels via a Tin Precursor

通过锡前体以高活性水平标记α发射(211)At单克隆抗体

Vaidyanathan, Ganesan; Pozzi, Oscar R; Choi, Jaeyeon; Zhao, Xiao-Guang; Murphy, Shawn; Zalutsky, Michael R

Observations on the Effects of Residualization and Dehalogenation on the Utility of N-Succinimidyl Ester Acylation Agents for Radioiodination of the Internalizing Antibody Trastuzumab

关于残留化和脱卤化对N-琥珀酰亚胺酯酰化剂用于内化抗体曲妥珠单抗放射性碘化应用效果的影响的观察

Chitneni, Satish K; Koumarianou, Eftychia; Vaidyanathan, Ganesan; Zalutsky, Michael R

Labeling Single Domain Antibody Fragments with Fluorine-18 Using 2,3,5,6-Tetrafluorophenyl 6-[(18)F]Fluoronicotinate Resulting in High Tumor-to-Kidney Ratios

利用 2,3,5,6-四氟苯基 6-[(18)F]氟烟酸酯对单域抗体片段进行氟-18 标记,可获得较高的肿瘤/肾脏比率

Zhou, Zhengyuan; McDougald, Darryl; Devoogdt, Nick; Zalutsky, Michael R; Vaidyanathan, Ganesan