日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Majusculamide-o, a simplified marine natural product analog, exhibits potent and specific cancer cell cytotoxicity

Majusculamide-o 是一种简化的海洋天然产物类似物,具有强效且特异性的癌细胞毒性。

Niklas Alexander Wahl ,Naiara Lebrón-Acosta # ,Michelle Pérez-Cuevas # ,Angel Hernandez-Mejias ,Dmitry Leshchiner ,Frederick A Valeriote ,Eduardo J E Caro-Diaz ,Sachi Horibata

Molecular mechanisms of phytoconstituents from selected Egyptian plants against non-small cell lung cancer using integrated in vitro network pharmacology and molecular docking approach

利用整合体外网络药理学和分子对接方法,研究埃及部分植物成分抗非小细胞肺癌的分子机制

Shaala, Lamiaa A; Youssef, Diaa T A; Ramadan, Mahmoud A; Khalifa, Azza A; Ibrahim, Reham S; Valeriote, Fred; Celik, Ismail; Dawood, Hend M

The Chemistry of Phytoplankton

浮游植物的化学

Liu, Xiaoying; Bian, Zhiwei; Hu, Shian; Dickinson, Cody F; Benjamin, Menny M; Jia, Jia; Tian, Yintai; Place, Allen; Hanna, George S; Luesch, Hendrik; Croot, Peter; Reddy, Maggie M; Thomas, Olivier P; Hardiman, Gary; Puglisi, Melany P; Yang, Ming; Zhong, Zhi; Lemasters, John J; Korte, Jeffrey E; Waters, Amanda L; Heltzel, Carl E; Williamson, R Thomas; Strangman, Wendy K; Valeriote, Fred; Tius, Marcus A; DiTullio, Giacomo R; Ferreira, Daneel; Alekseyenko, Alexander; Wang, Shengpeng; Hamann, Mark T; Wang, Xiaojuan

Further Probing the Properties of a Unique Sponge-derived Alkaloid Through the Isolation of a New (-)-(5E)-(8R)-(14Z)-Mycothiazole Analogue

通过分离一种新的(-)-(5E)-(8R)-(14Z)-霉噻唑类似物,进一步探究一种独特的海绵来源生物碱的性质

Gerke, Joe A; Odron, Sofia F; Kim, Juri; Dutta, Naibedya; Clarke, Jacqueline G; Media, Joseph; Coppage, David A; Oorloff, Maria; Alcala, Athena; Garcia, Gilberto; Kang, Marissa E F; Gerke, Cy L; Peterson, Jacob C; Morris, Joseph D; Higuchi-Sanabria, Ryo; Valeriote, Frederick A; Crews, Phillip; Johnson, Tyler A

A Versatile Chemoenzymatic Synthesis for the Discovery of Potent Cryptophycin Analogs

一种用于发现高效隐藻素类似物的多功能化学酶法合成

Schmidt, Jennifer J; Khatri, Yogan; Brody, Scott I; Zhu, Catherine; Pietraszkiewicz, Halina; Valeriote, Frederick A; Sherman, David H

The anti-MRSA compound 3-O-alpha-L-(2″,3″-di-p-coumaroyl)rhamnoside (KCR) inhibits protein synthesis in Staphylococcus aureus

抗 MRSA 化合物 3-O-α-L-(2″,3″-二-对香豆酰)鼠李糖苷 (KCR) 可抑制金黄色葡萄球菌的蛋白质合成

Nicholas J Carruthers, Paul M Stemmer, Joe Media, Ken Swartz, Xiaojuan Wang, Nicholas Aube, Mark T Hamann, Frederick Valeriote, Jiajiu Shaw

Computationally Assisted Discovery and Assignment of a Highly Strained and PANC-1 Selective Alkaloid from Alaska's Deep Ocean

利用计算机辅助方法发现并鉴定阿拉斯加深海中一种高应变且对PANC-1具有选择性的生物碱

Zou, Yike; Wang, Xiaojuan; Sims, James; Wang, Bin; Pandey, Pankaj; Welsh, Colin L; Stone, Robert P; Avery, Mitchell A; Doerksen, Robert J; Ferreira, Daneel; Anklin, Clemens; Valeriote, Frederick A; Kelly, Michelle; Hamann, Mark T

Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents

卡马霉素作为抗体药物偶联抗癌剂有效载荷的探索

Jehad Almaliti, Bailey Miller, Halina Pietraszkiewicz, Evgenia Glukhov, C Benjamin Naman, Toni Kline, Jeffrey Hanson, Xiaofan Li, Sihong Zhou, Frederick A Valeriote, William H Gerwick

Computationally Assisted Assignment of the Kadsuraols, a Class of Chemopreventive Agents for the Control of Liver Cancer.

利用计算机辅助方法确定卡苏拉醇类化合物(一类用于控制肝癌的化学预防剂)的用途

Wang Xiaojuan, Liu Jiabao, Pandey Pankaj, Fronczek Frank R, Doerksen Robert J, Chen Jiabao, Qi Xinzhu, Zhang Peicheng, Ferreira Daneel, Valeriote Frederick A, Sun Hua, Li Shuai, Hamann Mark T

The potential of achiral sponge-derived and synthetic bromoindoles as selective cytotoxins against PANC-1 tumor cells

非手性海绵衍生和合成溴吲哚作为针对PANC-1肿瘤细胞的选择性细胞毒素的潜力

Lorig-Roach, Nicholas; Hamkins-Indik, Frances; Johnson, Tyler A; Tenney, Karen; Valeriote, Frederick A; Crews, Phillip