Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire
用 HIV 包膜三聚体对奶牛进行免疫接种,可产生针对超长 CDRH3 库中的 V2-apex 的广泛中和抗体
期刊:PLoS Pathogens
影响因子:5.5
doi:10.1371/journal.ppat.1012042
Pilar X Altman, Gabriel Ozorowski, Robyn L Stanfield, Jeremy Haakenson, Michael Appel, Mara Parren, Wen-Hsin Lee, Huldah Sang, Jordan Woehl, Karen Saye-Francisco, Leigh M Sewall, Collin Joyce, Ge Song, Katelyn Porter, Elise Landais, Raiees Andrabi, Ian A Wilson, Andrew B Ward, Waithaka Mwangi, Vaugh