日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Extrinsic induction of apoptosis and tumor suppression via the p53-Reprimo-Hippo-YAP/TAZ-p73 pathway.

通过 p53-Reprimo-Hippo-YAP/TAZ-p73 通路诱导细胞凋亡和肿瘤抑制

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2413126122
Takikawa Masahiro, Nakano Airi, Krishnaraj Jayaraman, Tabata Yuko, Watanabe Yuzo, Okabe Atsushi, Sakaguchi Yukiko, Fujiki Ryoji, Mochizuki Ami, Tajima Tomoko, Sada Akane, Matsushita Shu, Wakabayashi Yuichi, Araki Kimi, Kaneda Atsushi, Ishikawa Fuyuki, Sadaie Mahito, Ohki Rieko
肿瘤
Hippo
P53
凋亡
发表日期：2025
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Deletion of the Mis12C-Binding Domain of CENP-C Promotes Chromosomal Aneuploidy in Cutaneous Squamous Cell Carcinoma

CENP-C 的 Mis12C 结合域缺失促进皮肤鳞状细胞癌的染色体非整倍体发生

期刊:Cancer Science
影响因子:4.3
doi:10.1111/cas.70216
Saito, Megumi; Okumura, Kazuhiro; Tokunaga, Yurika; Tanaka, Sora; Otoyama, Keisuke; Hasegawa, Yoshinori; Hara, Masatoshi; Hashimoto, Masakazu; Fujimori, Toshihiko; Fukagawa, Tatsuo; Wakabayashi, Yuichi
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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Targeting PAK1 is effective against cutaneous squamous cell carcinoma in a syngenic mouse model

在同基因小鼠模型中，靶向PAK1对皮肤鳞状细胞癌有效。

期刊:Cancer Science
影响因子:4.3
doi:10.1111/cas.16246
Okumura, Kazuhiro; Morinaga, Takao; Saito, Megumi; Tokunaga, Yurika; Otoyama, Keisuke; Tanaka, Sora; Isogai, Eriko; Kawazu, Masahito; Togashi, Yosuke; Hasegawa, Yoshinori; Wakabayashi, Yuichi
细胞生物学
肿瘤
肿瘤免疫
PAK1
发表日期：2024
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First-in-Human Evaluation of (18)F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B

首次人体评估 (18)F-PF-06445974，一种优先标记磷酸二酯酶-4B的PET放射性配体

期刊:
影响因子:
doi:10.2967/jnumed.122.263838
Wakabayashi, Yuichi; Stenkrona, Per; Arakawa, Ryosuke; Yan, Xuefeng; Van Buskirk, Maia G; Jenkins, Madeline D; Santamaria, Jose A Montero; Maresca, Kevin P; Takano, Akihiro; Liow, Jeih-San; Chappie, Thomas A; Varrone, Andrea; Nag, Sangram; Zhang, Lei; Hughes, Zoë A; Schmidt, Christopher J; Doran, Shawn D; Mannes, Andrew; Zanotti-Fregonara, Paolo; Ooms, Maarten; Morse, Cheryl L; Zoghbi, Sami S; Halldin, Christer; Pike, Victor W; Innis, Robert B
Human
发表日期：2022
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A wild-derived inbred mouse strain, MSM/Ms, provides insights into novel skin tumor susceptibility genes

一种源自野生种群的近交系小鼠MSM/Ms，为研究新型皮肤肿瘤易感基因提供了重要线索。

期刊:Experimental Animals
影响因子:1.2
doi:10.1538/expanim.21-0017
Okumura, Kazuhiro; Saito, Megumi; Wakabayashi, Yuichi
肿瘤
肿瘤免疫
多发性硬化症
发表日期：2021
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CENP-50 is required for papilloma development in the two-stage skin carcinogenesis model

在两阶段皮肤癌变模型中，CENP-50 是乳头状瘤发育所必需的。

期刊:Cancer Science
影响因子:4.3
doi:10.1111/cas.14533
Saito, Megumi; Kagawa, Naoko; Okumura, Kazuhiro; Munakata, Haruka; Isogai, Eriko; Fukagawa, Tatsuo; Wakabayashi, Yuichi
发育与干细胞
肿瘤
肿瘤免疫
皮肤癌
发表日期：2020
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Discovery, Radiolabeling, and Evaluation of Subtype-Selective Inhibitors for Positron Emission Tomography Imaging of Brain Phosphodiesterase-4D

脑磷酸二酯酶-4D正电子发射断层扫描成像亚型选择性抑制剂的发现、放射性标记和评价

期刊:ACS Chemical Neuroscience
影响因子:3.9
doi:10.1021/acschemneuro.0c00077
Wakabayashi, Yuichi; Telu, Sanjay; Dick, Rachel M; Fujita, Masahiro; Ooms, Maarten; Morse, Cheryl L; Liow, Jeih-San; Hong, Jinsoo S; Gladding, Robert L; Manly, Lester S; Zoghbi, Sami S; Mo, Xuesheng; D'Amato, Emily C; Sindac, Janice A; Nugent, Richard A; Marron, Brian E; Gurney, Mark E; Innis, Robert B; Pike, Victor W
神经科学
发表日期：2020
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Time-Series Analysis of Tumorigenesis in a Murine Skin Carcinogenesis Model

小鼠皮肤癌发生模型中肿瘤发生的时间序列分析

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-018-31349-x
Aoto, Yoshimasa; Okumura, Kazuhiro; Hachiya, Tsuyoshi; Hase, Sumitaka; Wakabayashi, Yuichi; Ishikawa, Fuyuki; Sakakibara, Yasubumi
肿瘤
肿瘤免疫
皮肤癌
发表日期：2018
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CENP-R acts bilaterally as a tumor suppressor and as an oncogene in the two-stage skin carcinogenesis model

在两阶段皮肤癌变模型中，CENP-R 既发挥抑癌基因的作用，又发挥癌基因的作用。

期刊:Cancer Science
影响因子:4.3
doi:10.1111/cas.13348
Okumura, Kazuhiro; Kagawa, Naoko; Saito, Megumi; Yoshizawa, Yasuhiro; Munakata, Haruka; Isogai, Eriko; Fukagawa, Tatsuo; Wakabayashi, Yuichi
肿瘤
肿瘤免疫
皮肤癌
发表日期：2017
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The parathyroid hormone regulates skin tumour susceptibility in mice

甲状旁腺激素调节小鼠皮肤肿瘤的易感性。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-017-11561-x
Okumura, Kazuhiro; Saito, Megumi; Yoshizawa, Yasuhiro; Munakata, Haruka; Isogai, Eriko; Miura, Ikuo; Wakana, Shigeharu; Yamaguchi, Midori; Shitara, Hiroshi; Taya, Choji; Karaplis, Andrew C; Kominami, Ryo; Wakabayashi, Yuichi
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2017
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