日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Trastuzumab deruxtecan efficacy, FcRn-facilitated penetration of the blood-tumor barrier, and distribution to tumor cells in HER2+ brain metastasis model systems

曲妥珠单抗德鲁替康的疗效、FcRn介导的血肿瘤屏障穿透以及在HER2阳性脑转移模型系统中向肿瘤细胞的分布

Khan, Imran; Kumar, Dinesh; Zhang, Wei; Difilippantonio, Simone; Robinson, Christina; Wei, Debbie; Lipkowitz, Stanley; Lake, Ross; Fleming, Ronald; Steeg, Patricia S

A CSF-1R inhibitor both prevents and treats triple-negative breast cancer brain metastases in hematogenous preclinical models.

CSF-1R 抑制剂在血液传播的临床前模型中既能预防又能治疗三阴性乳腺癌脑转移

Zhang Wei, Rahman Samiur, Wu Alex M L, Isanogle Kristine, Robinson Christina, Kumar Dinesh, Khan Imran, Wei Debbie, Zimmer Alexandra S, Fujii Takeo, Difilippantonio Simone, Lipkowitz Stanley, Steeg Patricia

Distinct uptake and elimination profiles for trastuzumab, human IgG, and biocytin-TMR in experimental HER2+ brain metastases of breast cancer.

曲妥珠单抗、人IgG和生物素-TMR在实验性HER2+乳腺癌脑转移中的吸收和消除特征不同

Silvestri Vanesa L, Tran Andy D, Chung Monika, Chung Natalie, Gril Brunilde, Robinson Christina, Difilippantonio Simone, Wei Debbie, Kruhlak Michael J, Peer Cody J, Figg W Douglas, Khan Imran, Steeg Patricia S

The murine metastatic microenvironment of experimental brain metastases of breast cancer differs by host age in vivo: a proteomic study.

乳腺癌脑转移小鼠的转移微环境随宿主年龄而变化:一项蛋白质组学研究

Hunt Allison L, Khan Imran, Wu Alex M L, Makohon-Moore Sasha C, Hood Brian L, Conrads Kelly A, Abulez Tamara, Ogata Jonathan, Mitchell Dave, Gist Glenn, Oliver Julie, Wei Debbie, Chung Monika A, Rahman Samiur, Bateman Nicholas W, Zhang Wei, Conrads Thomas P, Steeg Patricia S

HER2 antibody-drug conjugate controls growth of breast cancer brain metastases in hematogenous xenograft models, with heterogeneous blood-tumor barrier penetration unlinked to a passive marker

HER2抗体药物偶联物在血源性异种移植模型中控制乳腺癌脑转移瘤的生长,其血脑屏障穿透的异质性与被动标志物无关。

Gril, Brunilde; Wei, Debbie; Zimmer, Alexandra S; Robinson, Christina; Khan, Imran; Difilippantonio, Simone; Overstreet, Michael G; Steeg, Patricia S

H2A histone-fold and DNA elements in nucleosome activate SWR1-mediated H2A.Z replacement in budding yeast

核小体中的H2A组蛋白折叠和DNA元件激活出芽酵母中SWR1介导的H2A.Z替换

Ranjan, Anand; Wang, Feng; Mizuguchi, Gaku; Wei, Debbie; Huang, Yingzi; Wu, Carl

Imaging the fate of histone Cse4 reveals de novo replacement in S phase and subsequent stable residence at centromeres

对组蛋白Cse4命运的成像显示,其在S期发生从头替换,随后稳定地驻留在着丝粒处。

Wisniewski, Jan; Hajj, Bassam; Chen, Jiji; Mizuguchi, Gaku; Xiao, Hua; Wei, Debbie; Dahan, Maxime; Wu, Carl