日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tie2 activator 4E2 ameliorates diabetic nephropathy and synergizes with dapagliflozin in a mouse model.

Tie2 激活剂 4E2 可改善糖尿病肾病,并在小鼠模型中与达格列净产生协同作用

Jeong Da Som, Ko Soo Min, Lee Ji-Young, Han Hyo-Jeong, Lee Yerin, Lee Weon Sup, Lee Eun-Ah, Son Woo-Chan, Shin Jinho

A ligand-independent Tie2-activating antibody reduces vascular leakage in models of Clarkson disease

一种不依赖配体的Tie2激活抗体可减少克拉克森病模型中的血管渗漏。

Ablooglu, Ararat J; Desai, Abhishek; Yoo, Jin-San; Park, Cheon Ho; Lee, Eun-Ah; Kim, Bu Yeon; Park, Hyunsun; Lee, Young Ae; Shim, Sang Ryeol; Lee, Weon Sup; Druey, Kirk M

An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone

激动剂抗 Tie2 抗体可抑制胶质母细胞瘤侵袭区正常血管向肿瘤血管的转变

Eunhyeong Lee #, Eun-Ah Lee #, Eunji Kong, Haemin Chon, Melissa Llaiqui-Condori, Cheon Ho Park, Beom Yong Park, Nu Ri Kang, Jin-San Yoo, Hyun-Soo Lee, Hyung-Seok Kim, Sung-Hong Park, Seung-Won Choi, Dietmar Vestweber, Jeong Ho Lee, Pilhan Kim, Weon Sup Lee, Injune Kim

Preclinical pharmacokinetics, interspecies scaling, and pharmacokinetics of a Phase I clinical trial of TTAC-0001, a fully human monoclonal antibody against vascular endothelial growth factor 2

TTAC-0001(一种全人源抗血管内皮生长因子2单克隆抗体)的临床前药代动力学、种间缩放和I期临床试验的药代动力学

Lee, Weon Sup; Shim, Sang Ryeol; Lee, Seon Young; Yoo, Jin San; Cho, Sung Kweon

Phase I trial and pharmacokinetic study of tanibirumab, a fully human monoclonal antibody to vascular endothelial growth factor receptor 2, in patients with refractory solid tumors

tanibirumab(一种针对血管内皮生长因子受体 2 的全人源单克隆抗体)治疗难治性实体瘤患者的 I 期试验和药代动力学研究

Lee, Su Jin; Lee, Seon Young; Lee, Weon Sup; Yoo, Jin San; Sun, Jong-Mu; Lee, Jeeyun; Park, Se Hoon; Park, Joon Oh; Ahn, Myung-Ju; Lim, Ho Yeong; Kang, Won Ki; Park, Young Suk

Mitochondria-targeted aggregation induced emission theranostics: crucial importance of in situ activation

线粒体靶向聚集诱导发射治疗诊断:原位激活的重要性

Weon Sup Shin, Min-Goo Lee, Peter Verwilst, Joung Hae Lee, Sung-Gil Chi, Jong Seung Kim

Programmed activation of cancer cell apoptosis: A tumor-targeted phototherapeutic topoisomerase I inhibitor

程序性激活癌细胞凋亡:肿瘤靶向光治疗拓扑异构酶I抑制剂

Weon Sup Shin, Jiyou Han, Rajesh Kumar, Gyung Gyu Lee, Jonathan L Sessler, Jong-Hoon Kim, Jong Seung Kim

Anticancer activity of TTAC-0001, a fully human anti-vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) monoclonal antibody, is associated with inhibition of tumor angiogenesis

TTAC-0001是一种全人源抗血管内皮生长因子受体2 (VEGFR-2/KDR)单克隆抗体,其抗癌活性与抑制肿瘤血管生成有关。

Kim, Dong Geon; Jin, Younggeon; Jin, Juyoun; Yang, Heekyoung; Joo, Kyeung Min; Lee, Weon Sup; Shim, Sang Ryeol; Kim, Sung-Woo; Yoo, Jinsang; Lee, Sang Hoon; Yoo, Jin-San; Nam, Do-Hyun

TTAC-0001, a human monoclonal antibody targeting VEGFR-2/KDR, blocks tumor angiogenesis

TTAC-0001 是一种针对 VEGFR-2/KDR 的人类单克隆抗体,可阻断肿瘤血管生成

Weon Sup Lee, Bo-Jeong Pyun, Sung-Woo Kim, Sang Ryeol Shim, Ju Ryoung Nam, Ji Young Yoo, Younggeon Jin, Juyoun Jin, Young-Guen Kwon, Chae-Ok Yun, Do-Hyun Nam, Keunhee Oh, Dong-Sup Lee, Sang Hoon Lee, Jin-San Yoo

Hetero- and autoprocessing of the extracellular metalloprotease (Mpr) in Bacillus subtilis

枯草芽孢杆菌中细胞外金属蛋白酶 (Mpr) 的异体加工和自体加工

Chi Hye Park, Sang Jun Lee, Sung Gu Lee, Weon Sup Lee, Si Myung Byun